Results 61 to 70 of about 333,490 (283)
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Polling India via regression and post-stratification of non-probability online samples.
Recent technological advances have facilitated the collection of large-scale administrative data and the online surveying of the Indian population. Building on these we propose a strategy for more robust, frequent and transparent projections of the ...
Roberto Cerina, Raymond Duch
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A database of circumstellar OH masers
We present a new database of circumstellar OH masers at 1612, 1665, and 1667 MHz in the Milky Way galaxy. The database (version 2.4) contains 13655 observations and 2341 different stars detected in at least one transition.
Bunzel, F., Engels, D.
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Helicopter technology benefits and needs. Volume 2: Appendices [PDF]
Vehicle design, avionics and flight systems; safety and reliability; navigation, guidance and flight control; propulsion; auxiliary systems; human factors; and monitoring and diagnostic systems are the technology areas involved in solving operational and
Adams, R. J., Zuk, J.
core +1 more source
Incremental Parser Generation for Tree Adjoining Grammars
This paper describes the incremental generation of parse tables for the LR-type parsing of Tree Adjoining Languages (TALs). The algorithm presented handles modifications to the input grammar by updating the parser generated so far.
Sarkar, Anoop
core +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Language performance in computing table look- up auxiliaries on microcomputers
Microcomputers are increasingly employed in modelling and, with their growth in usage, new versions of well-known simulation languages have been developed for small computers. However, the use of third-generation programming languages in simulation abides.
openaire +1 more source

