Results 81 to 90 of about 334,818 (282)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Language performance in computing table look- up auxiliaries on microcomputers

open access: yesApplied Mathematical Modelling, 1989
Microcomputers are increasingly employed in modelling and, with their growth in usage, new versions of well-known simulation languages have been developed for small computers. However, the use of third-generation programming languages in simulation abides.
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

New Mathematical Models for Coefficients of Hydrodynamic Resistance to Rotation and Friction of Sliding Bearings of Ship Propulsion System for non Newtonian Lubricants [PDF]

open access: yesTransNav
The boundary value problem for the Reynolds differential equations for the lubricating layer in the sliding bearings of ship power plants and auxiliary ship equipment is solved by the boundary variation method. As a result, analytical representations for
Olexandr Kryvyi   +2 more
doaj   +1 more source

Flap-lag-torsion aeroelastic stability of a circulation control rotor in forward flight [PDF]

open access: yes
The aeroelastic stability of a circulation control rotor blade undergoing three degrees of motion (flap, lag, and torsion) is investigated in forward flight.
Chopra, Inderjit, Hong, Chang-Ho
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Analysis of nonlinear fractional-order Fisher equation using two reliable techniques

open access: yesOpen Physics
In this article, the solution to the time-fractional Fisher equation is determined using two well-known analytical techniques. The suggested approaches are the new iterative method and the optimal auxiliary function method, with the fractional derivative
Ahmad Hijaz   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Garrison of the Roman Fort at Porolissum (Dacia). The Analysis of the Tile-Stamps

open access: yesOpen Archaeology, 2018
The author is dealing with the tile-stamps found in the Roman auxiliary fort at Porolissum attempting to establish which of the many units recorded on tile-stamps stayed in garrison at Porolissum.
Oprean Coriolan Horatiu
doaj   +1 more source

A database of circumstellar OH masers

open access: yes, 2015
We present a new database of circumstellar OH masers at 1612, 1665, and 1667 MHz in the Milky Way galaxy. The database (version 2.4) contains 13655 observations and 2341 different stars detected in at least one transition.
Bunzel, F., Engels, D.
core   +1 more source

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