Results 101 to 110 of about 42,339 (298)

Fast and Accurate Calculation of Owen's T Function

See paper for mathematical introduction.
Mike Patefield
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Разработка и систематизация алгоритмов управления электрооборудованием энергосберегающих технологических линий обработки молока

Agricultural Science, 2015
The authors have developed and systematized electrical equipment control algorithms of milk processing energy-efficient lines in this article. Control objects were divided into standard sections, electrical equipment was divided into functional units. We
ВОЛКОНОВИЧ Ливиу, КУШНИР М. Г. , ВОЛКОНОВИЧ А. Л. , СТЕОПКА О. Г., СЛИПЕНКИ В. Е., КИРИЯК И. И., ПОПА А. Г.   +6 more
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Supplementary Material for"Large-scale cooperation driven by reputation,not fear of divine punishment"

, 2019
This file contains additional information about description of control variables,details of religious questionnaire, demographic tables of communities, game results distribution, figures & tables providing auxiliary and confirmatory ...
Ruth Mace (61511), Yuan Chen (9740), Erhao Ge (7130465), Jiajia Wu (535986)   +3 more
core   +2 more sources

Comparative analysis of the withdrawal of thin-film flow of a third-grade fluid under the influence of MHD using two homotopy based techniques

Kuwait Journal of Science
The purpose of this work is to examine the thin film flow of a third grade fluid having appropriate boundary conditions using two homotopy based techniques, that is, the optimal homotopy asymptotic method with DJ polynomial (OHAM-DJ) and the asymptotic ...
Azzh Saad Alshehry, Musaad S. Aldhabani, Alamgeer Khan, Ahmed Shafee   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Kierunki Możliwych Usprawnień w Obliczeniach Łuków

Engineering Transactions, 1953
This paper discusses the possible improvements in the statical computation of three main types of arches from the point of view of engineering practice. These are parabolic, elliptic (with vertical major axis) and circular arches.
W. Wierzbicki
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source