Results 101 to 110 of about 2,583,808 (327)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Hospital Auxiliary Records

, 2016
The Kleberg Memorial Hospital Auxiliary, formerly known as Kleberg County Hospital Auxiliary, came into being on February 14, 1962, with the first election of officers and the ratification of its by-laws by members of the Community Service Department of ...
Members of the Auxiliary
core   +1 more source

A mechanism-material-matrix framework for electrochemical advanced oxidation of persistent organic pollutants in wastewater [PDF]

RSC Advances
Persistent organic pollutants remain difficult to treat because disappearance of the parent compound can conceal incomplete mineralization, toxic intermediates, or high energy demand.
Zhao Zhang, Guanghua Jing, Qiangqiang Lu, Ning Zhao, Zhikun Chen   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Closed-Form Heteroclinic Orbits for a Three-Parameter Dynamical System Using a Modified Optimal Parametric Iteration Method

Mathematics
Numerous applications from electrical engineering and mechanical structures are mathematically modeled using dynamical systems theory. Our paper concerns the behaviors of a 3D dynamic system in terms of damped or periodical oscillations and asymptotic ...
Remus-Daniel Ene, Romeo Negrea, Rodica Badarau, Nicolina Pop   +3 more
doaj   +1 more source

New Optimum solutions of The Time-Fractional Fitzhugh-Nagumo Equations

International Journal of Analysis and Applications
The purpose and objective of the present work are to show the reliability and effectiveness of the newly developed semi-numerical method, i-e, the Optimal Auxiliary Function method OAFM, by solving the fractional problems of Fitzhugh-Nagumo.
T. Alzkari, Adil Khan, M. Fiza, H. Ullah, Aasim Ullah Jan, A. Akgül, A. Hendy, Ilyas Khan, A. B. Albidah, W. Koh   +9 more
semanticscholar   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

QuASAR: A Question-Driven Structure-Aware Approach for Table-to-Text Generation

Annual Meeting of the Association for Computational Linguistics
Table-to-text generation aims to automatically produce natural language descriptions from structured or semi-structured tabular data. Unlike traditional text generation tasks, it requires models to accurately understand and represent table structures ...
Weijie Liu, Yibin Zheng, Fang-yuan Kong
semanticscholar   +1 more source

Pulaski Day Parade Polish Women's Auxiliary Post 121

, 1965
Group photograph of the Women's Auxiliary Post 121 during the Pulaski Day ...

core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source