Results 111 to 120 of about 2,583,808 (327)
RSS Tracking Control for AVs Under Bayesian-Network-Based Intelligent Learning Scheme
ActuatorsIn complex real-world traffic environments, the task of automatic lane changing becomes extremely challenging for vehicle control systems. Traditional control methods often lack the flexibility and intelligence to accurately capture and respond to ...
Kun Zhang, Kezhen Han, Nanbin Zhao
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Demonstratio MathematicaIn this paper, we propose and study a new ternary three-dimensional fractional reaction-diffusion model. The model combines Caputo fractional derivatives in time with Riesz fractional derivatives in space.
Kosari Saeed, Guan Hao
doaj +1 more source
Columbia University College of Physicians and Surgeons, Vanderbilt Clinic Auxiliary annual report
Shelving title: Columbia University, Vanderbilt Clinic Auxiliary annual reportDescription based on: 1909.Spine title: Columbia University College of Physicians and Surgeons, Vanderbilt Clinic, Vanderbilt Clinic Auxiliary, annual report.Mode of access ...
Columbia University. Vanderbilt Clinic Auxiliary.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Proceedings of the ... annual session of the Baptist Daughters of Zion Auxiliary ... [serial].
Description based on: 43rd (1921).Mode of access ...
Baptist Daughters of Zion Auxiliary.
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An Intelligent Auxiliary Vacuum Brake System [PDF]
, 2009 The purpose of this paper focuses on designing an intelligent, compact, reliable, and robust auxiliary vacuum brake system (VBS) with Kalman filter and self-diagnosis scheme.
Tong, Chia-Chang +3 more
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