Results 121 to 130 of about 2,333,017 (293)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Pitfalls of imputing using incomplete auxiliary variables

open access: yesAmerican Journal of Epidemiology
We respond to Madley-Dowd et al's recent article in American Journal of Epidemiology. We show that standard imputation algorithms can fail for simple graphs (such as those used in Madley-Dowd et al's simulation study) even when the full data distribution is identified and an appropriate imputation estimator would be straightforward to design.
Maya B Mathur, Ilya Shpitser
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Columbia University College of Physicians and Surgeons, Vanderbilt Clinic Auxiliary annual report

open access: yes
Shelving title: Columbia University, Vanderbilt Clinic Auxiliary annual reportDescription based on: 1909.Spine title: Columbia University College of Physicians and Surgeons, Vanderbilt Clinic, Vanderbilt Clinic Auxiliary, annual report.Mode of access ...
Columbia University. Vanderbilt Clinic Auxiliary.
core  

Auxiliary-Variable Adaptive Control Barrier Functions

open access: yesCoRR
This paper addresses the challenge of ensuring safety and feasibility in control systems using Control Barrier Functions (CBFs). Existing CBF-based Quadratic Programs (CBF-QPs) often encounter feasibility issues due to mixed relative degree constraints, input nullification problems, and the presence of tight or time-varying control bounds, which can ...
Shuo Liu, Wei Xiao 0003, Calin A. Belta
openaire   +3 more sources

Research on Spatial Interpolation of Rainfall Based on GIS-A Case Study of Hunan Province

open access: yesShuitu baochi yanjiu, 2020
Rainfall data are the basic for regional hydrological simulation, water resources analysis and management, geological hazard warning, etc. It is of great theoretical and practical significance to improve the interpolation accuracy of rainfall data. Hunan
YANG Kuanda   +5 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Proceedings of the ... annual session of the Baptist Daughters of Zion Auxiliary ... [serial].

open access: yes
Description based on: 43rd (1921).Mode of access ...
Baptist Daughters of Zion Auxiliary.
core  

Multiple imputation using auxiliary imputation variables that only predict missingness can increase bias due to data missing not at random

open access: yesBMC Medical Research Methodology
Background Epidemiological and clinical studies often have missing data, frequently analysed using multiple imputation (MI). In general, MI estimates will be biased if data are missing not at random (MNAR).
Elinor Curnow   +4 more
doaj   +1 more source

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