Results 61 to 70 of about 2,333,017 (293)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Towards counterfactual fairness through auxiliary variables

CoRR
The challenge of balancing fairness and predictive accuracy in machine learning models, especially when sensitive attributes such as race, gender, or age are considered, has motivated substantial research in recent years. Counterfactual fairness ensures that predictions remain consistent across counterfactual variations of sensitive attributes, which ...
Bowei Tian, Ziyao Wang, Shwai He, Wanghao Ye, Guoheng Sun, Yucong Dai, Yongkai Wu, Ang Li 0005   +7 more
openaire   +4 more sources

Monitoring process variability using auxiliary information [PDF]

Computational Statistics, 2007
A construction of Shewhart-type control charts is considered for the changes of variance of a controlled variable \(Y\) in the case when some auxiliary variable \(X\) is also observed. Bivariate normality of \((X,Y)\) is assumed. The chart is based on a regression-type estimate for the variance of \(Y\) by observations on \(X\). The central line, lower
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Imputation of a true endpoint from a surrogate: application to a cluster randomized controlled trial with partial information on the true endpoint

BMC Medical Research Methodology, 2003
Background The Anglia Menorrhagia Education Study (AMES) is a randomized controlled trial testing the effectiveness of an education package applied to general practices.
Duffy Stephen W, Nixon Richard M, Fender Guy RK   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Accuracy and uncertainty assessment on geostatistical simulation of soil salinity in a coastal farmland using auxiliary variable

, 2013
Understanding the spatial soil salinity aids farmers and researchers in identifying areas in the field where special management practices are required.
Yao, R. J., Shao, H. B., Yang, J. S.
core   +1 more source

Improved estimator for the estimation of sensitive variable using ORRT models

Research in Statistics
In this study, we concern with the improved estimation of sensitive variable when there is non-response and measurement error on sensitive variable but the auxiliary variable is non sensitive in nature.
Sunil Kumar, Chanda Rani
doaj   +1 more source

Use of Double Sampling Scheme in Estimating the Mean of Stratified Population under Non-response

Statistica, 2015
The present paper focuses on the use of double sampling scheme in stratified random sampling for estimating the population mean in the presence of non-response. Motivated by Khoshnevisan et al (2007), we have proposed a family of combined-type estimators
Manoj Kumar Chaudhary, Amit Kumar
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source