Results 81 to 90 of about 74,731 (304)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A Comparative Study of New Ratio-Type Family of Estimators Under Stratified Two-Phase Sampling

open access: yesMathematics
Two-phase sampling is a useful technique for sample surveys, particularly when prior auxiliary data is not accessible. The ranks of the auxiliary variable often coincide with those of the research variable when two variables are correlated.
Abdulaziz S. Alghamdi, Hleil Alrweili
doaj   +1 more source

Elasto-plastic solution to expansion of a spherical cavity in dilatant sand

open access: yesYantu gongcheng xuebao, 2017
The current solutions to spherical cavity expansion can not properly consider the peak strength and dilatancy of the sand, and thus there is some dispency between the solution and the practical situation.
LI Lin 1, 2, LI Jing-pei 1,2, SUN De-an 3, LI Xian-feng 1, 2
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Optimal Neutrosophic Difference to Log-Type Estimator for Population Mean: Some Numerical and Simulation Studieshttps://fs.unm.edu/NSS/11NeutrosophicDifference.pdf [PDF]

open access: yesNeutrosophic Sets and Systems
Indeterminacy in the data are commonly observed in various fields like biomedicine, finance, marketing and other sphere of sciences, where classical statistical methods is a challenging task to deal such type of data.
SM Afsar Basha, Mahamood Usman
doaj   +1 more source

Dynamic performance of auxiliary hydraulic power unit based electro-hydraulic variable speed drive system

open access: yes, 2017
Inability of dynamic performances, especially the acceleration response, strongly inhibits the application of electro-hydraulic variable speed drive, even though its intrinsic energy-saving potential.
Ming Xu   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Neutrosophic Exponential Ratio-Type Estimator for Finite Population Mean [PDF]

open access: yesNeutrosophic Sets and Systems
This paper proposes a neutrosophic exponential-type estimator for finite population mean estimation using auxiliary variables. Traditional statistical estimators often fall short when handling vague or uncertain data.
Anisha Taneja   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A note on the use of an origin shift in survey sampling: a conceptual perspective

open access: yesStatistica, 2013
In this paper, a simple origin shifted auxiliary variable z has been considered when the values of the main auxiliary variable x are completely known. The usability of z has been demonstrated both analytically and geometrically.
Jagatananda Sahoo   +2 more
doaj   +1 more source

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