Results 81 to 90 of about 468,328 (281)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Continuous and discrete transformations of a one-dimensional porous medium equation

, 1999
We consider the one-dimensional porous medium equation $u_t=\left (u^nu_x \right )_x+\frac{\mu}{x}u^nu_x$. We derive point transformations of a general class that map this equation into itself or into equations of a similar class.
Bluman G.W., Bluman G.W., Gandarias M.L., Gandarias M.L., Ibragimov N.H., Kingston J.G., Kingston J.G., Sophocleous C., Sophocleous C.   +8 more
core   +1 more source

Re-using Auxiliary Variables for MaxSAT Preprocessing [PDF]

2015 IEEE 27th International Conference on Tools with Artificial Intelligence (ICTAI), 2015
Solvers for the maximum satisfiability (MaxSAT) problem -- a well-known optimization variant of Boolean satisfiability (SAT) -- are finding an increasing number of applications. Preprocessing has proven an integral part of the SAT-based approach to efficiently solving various types of real-world problem instances.
Jeremias Berg, Paul Saikko, Matti Jarvisalo   +2 more
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Imputation of a true endpoint from a surrogate: application to a cluster randomized controlled trial with partial information on the true endpoint

BMC Medical Research Methodology, 2003
Background The Anglia Menorrhagia Education Study (AMES) is a randomized controlled trial testing the effectiveness of an education package applied to general practices.
Duffy Stephen W, Nixon Richard M, Fender Guy RK   +2 more
doaj   +1 more source

A well-balanced gas kinetic scheme for Navier-Stokes equations with gravitational potential

, 2019
The hydrostatic equilibrium state is the consequence of the exact hydrostatic balance between hydrostatic pressure and external force. Standard finite volume or finite difference schemes cannot keep this balance exactly due to their unbalanced truncation
Chen, Songze, Guo, Zhaoli, Xu, Kun
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Improved estimator for the estimation of sensitive variable using ORRT models

Research in Statistics
In this study, we concern with the improved estimation of sensitive variable when there is non-response and measurement error on sensitive variable but the auxiliary variable is non sensitive in nature.
Sunil Kumar, Chanda Rani
doaj   +1 more source

Use of Double Sampling Scheme in Estimating the Mean of Stratified Population under Non-response

Statistica, 2015
The present paper focuses on the use of double sampling scheme in stratified random sampling for estimating the population mean in the presence of non-response. Motivated by Khoshnevisan et al (2007), we have proposed a family of combined-type estimators
Manoj Kumar Chaudhary, Amit Kumar
doaj   +1 more source

A partial solution for lossless source coding with coded side information [PDF]

, 2006
This paper considers the problem, first introduced by Ahlswede and Körner in 1975, of lossless source coding with coded side information. Specifically, let X and Y be two random variables such that X is desired losslessly at the decoder while Y serves as
Effros, Michelle, Marco, Daniel
core