Results 71 to 80 of about 57,992 (261)

Improving inference of Gaussian mixtures using auxiliary variables [PDF]

Statistical Analysis and Data Mining: The ASA Data Science Journal, 2015
AbstractExpanding a lower‐dimensional problem to a higher‐dimensional space and then projecting back is often beneficial. This article rigorously investigates this perspective in the context of finite mixture models, specifically how to improve inference for mixture models by using auxiliary variables. Despite the large literature in mixture models and
Andrea Mercatanti, Fan Li, Fabrizia Mealli   +2 more
openaire   +6 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Modelling Seasonal GWR of Daily PM2.5 with Proper Auxiliary Variables for the Yangtze River Delta

Remote Sensing, 2017
Over the past decades, regional haze episodes have frequently occurred in eastern China, especially in the Yangtze River Delta (YRD). Satellite derived Aerosol Optical Depth (AOD) has been used to retrieve the spatial coverage of PM2.5 concentrations. To
Man Jiang, Weiwei Sun, Gang Yang, Dianfa Zhang   +3 more
doaj   +1 more source

A CLASS OF REGRESSION-CUM-RATIO ESTIMATORS IN TWO-PHASE SAMPLING FOR UTILIZING INFORMATION FROM HIGH RESOLUTION SATELLITE DATA [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012
Two-phase sampling design offers a variety of possibilities for effective use of auxiliary information such as those from high resolution remote sensing data. Continuous satellite data with large area coverage provide scope for deriving population values
B. K. Handique
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Comparison of the local pivotal method and systematic sampling for national forest inventories

Forest Ecosystems, 2020
Background The local pivotal method (LPM) utilizing auxiliary data in sample selection has recently been proposed as a sampling method for national forest inventories (NFIs).
Minna Räty, Mikko Kuronen, Mari Myllymäki, Annika Kangas, Kai Mäkisara, Juha Heikkinen   +5 more
doaj   +1 more source

Two-stage sampling in the estimation of growth parameters and percentile norms: sample weights versus auxiliary variable estimation

BMC Medical Research Methodology, 2021
Background The use of auxiliary variables with maximum likelihood parameter estimation for surveys that miss data by design is not a widespread approach, despite its documented improved efficiency over traditional approaches that deploy sampling weights.
George Vamvakas, Courtenay Norbury, Andrew Pickles   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Integrating Environmental Variables into Geostatistical Interpolation: Enhancing Soil Mapping for the MEDALUS Model in Montenegro

Land
Geostatistical methods are important in analyzing natural resources providing input data for complex mathematical models that address environmental processes and their spatial distribution. Ten interpolation methods and one empirical-based classification
Stefan Miletić, Jelena Beloica, Predrag Miljković   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source