Results 81 to 90 of about 421,329 (326)
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Factor Graphs for Quantum Probabilities
A factor-graph representation of quantum-mechanical probabilities (involving any number of measurements) is proposed. Unlike standard statistical models, the proposed representation uses auxiliary variables (state variables) that are not random variables.
Loeliger, Hans-Andrea +1 more
core +1 more source
Auxiliary Variables in Temporal Specifications
Assertion-based verification (ABV) for IP blocks given as synchronous RTL (register transfer level) descriptions has now widely gained acceptance. The challenge addressed here is ABV for systems on chip (SoC) modeled at the system level in SystemC TLM (Transactional Level Modeling).
openaire +2 more sources
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Re-using Auxiliary Variables for MaxSAT Preprocessing [PDF]
Solvers for the maximum satisfiability (MaxSAT) problem -- a well-known optimization variant of Boolean satisfiability (SAT) -- are finding an increasing number of applications. Preprocessing has proven an integral part of the SAT-based approach to efficiently solving various types of real-world problem instances.
Jeremias Berg +2 more
openaire +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Auxiliary fields and the flux tube model
It is possible to eliminate exactly all the auxiliary fields (einbein fields) appearing in the rotating string Hamiltonian to obtain the classical equations of motion of the relativistic flux tube model.
Buisseret, Fabien, Semay, Claude
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The complex frequency shifted (CFS) perfectly matched layer (PML) is proposed for the two-dimensional auxiliary differential equation (ADE) finite-difference time-domain (FDTD) method combined with Associated Hermite (AH) orthogonal functions.
Feng Jiang +4 more
doaj +1 more source

