Results 41 to 50 of about 56,556 (274)

Nanozyme‐Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy

Advanced Science, EarlyView.
A nanozyme–integrated hydrogel (PTC‐MP) exhibiting with mild photothermal effects is constructed, and a “3R” (restrain‐restore‐reinforce) strategy is proposed for diabetic osteoarthritis (DOA) treatment based on advanced glycation end products (AGEs) targeting.
Rui Chen, Yanguo Su, Guiyuan Zhao, Jiaojiao Tao, Qijie Diao, Guangli Xiang, Tianze Jiang, Lu Han, Xia Zhao   +8 more
wiley   +1 more source

Hawkins II and III Talus Neck Fractures: Complication Rates and Utility of Hawkins Sign

Foot & Ankle Orthopaedics
Category: Trauma; Ankle Introduction/Purpose: Talus neck fractures typically result from hyperdorsiflexion in high-impact accidents like motor vehicle crashes and falls from significant heights.
Logan Lake, Sarah Kurkowski MD, Augusto Roca BS, Henry Albert Kuechly BS, Andres Mor Huertas BS, Michael Thimmesch BS, Peter Spencer BS, Richard T. Laughlin MD   +7 more
doaj   +1 more source

MRI-semiotics of the gluteal muscles in patients with avascular necrosis of the femoral head and Legg-Calve-Perthes disease [PDF]

Гений oртопедии, 2019
Objective To explore the gluteal muscles in patients with avascular necrosis of the femoral head and Legg-Calve-Perthes disease using magnetic resonance imaging (MRI).
Galina V. Diachkova, Mikhail P. Teplenky, Konstantin A. Diachkov, Tat'iana A. Larionova   +3 more
doaj   +1 more source

Idiopathic avascular maxillary necrosis: A case report

Oral and Maxillofacial Surgery Cases, 2023
Osteonecrosis of the jaw (ONJ) is a rare phenomenon that usually occurs in individuals exposed to certain medications, radiation, or physical or chemical insults that ultimately result in compromised vascularity of the jaws. However, in some cases, it is
S.M. Abdullah Salman, Oam Parkash, Mehak Anis, Muhammad Rameez, Hammad Ul-Haq   +4 more
doaj   +1 more source

Outcomes of total hip arthroplasty, as a salvage procedure, following failed internal fixation of intracapsular fractures of the femoral neck: a systematic review and meta-analysis. [PDF]

, 2016
AIMS: The optimal management of intracapsular fractures of the femoral neck in independently mobile patients remains open to debate. Successful fixation obviates the limitations of arthroplasty for this group of patients.
Archibeck MJ, Blomfeldt R, Broderick JM, Burns PB, Charnley J, Flugsrud GB, Franzén H, Garden RS, Harris WH, Hunt SM, Katz S, McKinley JC, Mehlhoff T, Moher D, Neander G, Nilsson LT, Nilsson LT, Oztürkmen Y, Schmidt AH, Winemaker M, Yang J, Zhang X   +21 more
core   +2 more sources

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Time‐ and dose‐related pathological changes in knee osteoarthritis rat model induced by monosodium iodoacetate

Animal Models and Experimental Medicine, EarlyView.
Time‐ and dose‐related pathological changes of knee osteoarthritis rat model induced by monosodium iodoacetate. Abstract Knee osteoarthritis (KOA) is a chronic degenerative disease. Monosodium iodoacetate (MIA) induction is the most commonly used therapeutic effect evaluation and mechanism of action research model; we observed a lack of standardization
Wei Pu, Qi Liu, Shuyan Xue, Siyuan Li, Nan Nan, Yang Liu, Huiqin Hao   +6 more
wiley   +1 more source

Avascular necrosis of the right femoral head in female patient with Systemic Lupus Erythematosus

Indonesian Journal of Rheumatology, 2018
Avascular necrosis (also known as osteonecrosis, aseptic necrosis, or ischemic necrosis) represents collection of pathologic conditions from various etiologies causing impairment of blood supply to particular bone resulting in bone cellular death ...
A Sinaga, H Nufus, Bambang Setiyohadi
doaj   +1 more source

Immunological Profiling suggests an Association between Treg dysfunction and Pain in Knee Osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Background Pain is the hallmark symptom of osteoarthritis (OA) and its biological drivers remain poorly understood. While the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular regulatory T cells (Tregs), is not well understood. Methods We performed omics profiling of peripheral blood from 46
Marie Binvignat, Johanna Dubois, Maria Marco Salvador, Paul Stys, Fabien Pitoiset, Alexandra Roux, Michèle Sastre, Signe Hassler, Roberta Lorenzon, Claire Ribet, Vanessa Mhanna, Hélène Vantomme, Leslie Adda, Pierre Barennes, Nicolas Coatnoan, Kenz Le Gouge, Caroline Aheng, Alice Courties, Lise Minssen, Atul J. Butte, Adrien Six, Michelle Rosenzwajg, Nicolas Tchitchek, Francis Berenbaum, David Klatzmann, Encarnita Mariotti‐Ferrandiz, Jérémie Sellam   +26 more
wiley   +1 more source

Mathematical models of avascular cancer [PDF]

, 2005
This review will outline a number of illustrative mathematical models describing the growth of avascular tumours. The aim of the review is to provide a relatively comprehensive list of existing models in this area and discuss several representative ...
Chapman, S. J., Maini, P. K., Roose, T.
core