Results 1 to 10 of about 42,834 (274)

Short-Term Efficacy and Safety of Secukinumab for Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of RCTs

Mediators of Inflammation, 2020
Secukinumab is a novel IL-17A inhibitor that has been confirmed to be effective for treating PsA and RA. Several studies have demonstrated that secukinumab also provides benefits for AS patients. Thus, we performed a meta-analysis of RCTs to evaluate the
Yu Zhou, Jinhui Ma, Juncheng Ge, Bailiang Wang, Debo Yue, Weiguo Wang   +5 more
doaj   +1 more source

A case of completed course multifocal osteonecrosis (MFON) during pregnancy due to primary antiphospholipid syndrome

Egyptian Rheumatology and Rehabilitation, 2022
Osteonecrosis of both shoulders and hips is a rare presentation of primary antiphospholipid syndrome. A female patient aged 23 years old with no systemic diseases has her only complaint which was pain and limitations in both hips followed by both ...
Aya El Shintenawy, Soha Khallaf, Esraa El Shentenawy, Ali El Deeb   +3 more
doaj   +1 more source

Phase-contrast imaging with synchrotron hard X-ray reveals the effect of icariin on bone tissue morphology and microstructure in rabbits with early glucocorticoid-induced osteonecrosis of the femoral head

Frontiers in Cell and Developmental Biology, 2023
Background: Phase-contrast imaging (PCI) with synchrotron hard X-ray was used to observe the changes in bone tissue morphology and microstructure in rabbit models of early glucocorticoid-induced osteonecrosis of the femoral head (ONFH), and to evaluate ...
Xu Yang, Xu Yang, Lijun Shi, Aifeng Li, Fuqiang Gao, Wei Sun, Wei Sun, Zirong Li   +7 more
doaj   +1 more source

Radiographic sclerosis with intraoperative fragile bone in skeletal fluorosis: a case report

Frontiers in Surgery
IntroductionSkeletal fluorosis is a rare toxic osteopathy characterized by massive bone fluoride fixation. The disease is an endemic problem in some parts of the world and is the result of the prolonged ingestion or inhalation of large amounts of ...
Weikun Hou, Lin Liu, Wensen Jing, Chao Lu, Yangquan Hao   +4 more
doaj   +1 more source

The relationship between apolipoprotein genes polymorphisms and susceptibility to osteonecrosis of the femoral head: a meta-analysis

Lipids in Health and Disease, 2018
Background The objective of this study was to evaluate whether apolipoprotein gene polymorphisms confer susceptibility to osteonecrosis of the femoral head (ONFH).
Yangquan Hao, Hao Guo, Zhaochen Xu, Handeng Qi, Yugui Wang, Chao Lu, Jie Liu, Puwei Yuan   +7 more
doaj   +1 more source

Existing hip joint disease is associated with an increased incidence of hip fracture in adults: A retrospective survey of 9710 individuals from a single center

Heliyon
Objective: In hip disease patients, pain and movement restrictions might cause changes in bone strength and increase the likelihood of falls, finally leading to hip fracture.
Bo Liu, Xiao Chen, Mengnan Li, Xiaoxuan Zhang, Binquan Zhang, Huijie Li   +5 more
doaj   +1 more source

Polymer Scaffolds-Enhanced Bone Regeneration in Osteonecrosis Therapy

Frontiers in Bioengineering and Biotechnology, 2021
Osteonecrosis without effective early treatment eventually leads to the collapse of the articular surface and causes arthritis. For the early stages of osteonecrosis, core decompression combined with bone grafting, is a procedure worthy of attention and ...
Hengliang Dong, Tongtong Zhu, Mingran Zhang, Dapeng Wang, Xukai Wang, Guanning Huang, Shuaishuai Wang, Minglei Zhang   +7 more
doaj   +1 more source

OSTEONECROSIS OF THE JAW

The Journal of the American Dental Association, 2011
The paper concerns osteonecrosis of the jaw (ONJ). It is a rare but serious clinical condition. It can develop in patients treated in oncologic doses with bisphosphonates but also with denosumab. In osteoporosis ONJ seems to be very rare. Definition, pathogenesis, risk factors, prevention and treatment, and the frequency of ONJ are presented.
openaire   +5 more sources

Knee osteonecrosis incidence from two real-world data sources

Osteoarthritis and Cartilage Open, 2021
Background: Anti-nerve growth factor (NGF) has shown promise for osteoarthritis (OA) pain efficacy, but an unanticipated joint safety signal occurred in trials.
Jean W. Liew, Seoyoung C. Kim, Christine Peloquin, David T. Felson, Yinzhu Jin, Joyce Lii, Tuhina Neogi   +6 more
doaj   +1 more source

Utility of quantitative standardized uptake value from pre-operative bone SPECT/CT for predicting post-surgical MRONJ healing response

EJNMMI Research
Background Medication-related osteonecrosis of the jaw (MRONJ) is a challenging condition often associated with long-term use of anti-resorptive medications.
Jung-Hyun Park, Da-Mi Yoon, Hai-Jeon Yoon, Jin-Woo Kim   +3 more
doaj   +1 more source