Results 1 to 10 of about 60,884 (258)

Impaired dexamethasone-related increase of anticoagulants is associated with the development of osteonecrosis in childhood acute lymphoblastic leukemia [PDF]

Haematologica, 2008
Coagulation alterations may be involved in osteonecrosis in childhood acute lymphoblastic leukemia. Retrospectively, we evaluated the available coagulation parameters at diagnosis and during induction treatment of 161 acute lymphoblastic leukemia ...
Mariel L. te Winkel, Inge M. Appel, Rob Pieters, Marry M. van den Heuvel-Eibrink   +3 more
doaj   +5 more sources

Engineered three-dimensional scaffolds for enhanced bone regeneration in osteonecrosis

Bioactive Materials, 2020
Osteonecrosis, which is typically induced by trauma, glucocorticoid abuse, or alcoholism, is one of the most severe diseases in clinical orthopedics. Osteonecrosis often leads to joint destruction, and arthroplasty is eventually required.
Mingran Zhang, Duoyi Zhao, Jian-Xun Ding
exaly   +3 more sources

Osteonecrosis

Orthopaedics and Trauma, 2018
Introduction: decreased blood flow to the head of femur is a degenerative process leading to cell death and eventually to osteonecrosis. It occurs mostly in people aged 20-40 and is a common presentation for orthopedic surgery consultation. The surgeons usually decide management plan on a case basis, and depending on the age of the patient, gender ...
Eustathios Kenanidis, Anastasios Nektarios Tzavellas, Andreas Leonidou, Eleftherios Tsiridis, Arkan S. Sayed-Noor, Bakir Kadum, Karl Brabants, Peter Mertens, Bogdan Nikolae Deleanu   +8 more
  +7 more sources

The diagnostic value of blood metagenomic next-generation sequencing in patients with acute hematogenous osteomyelitis

Frontiers in Cellular and Infection Microbiology, 2023
AimsThis study aims to evaluate the diagnostic value of blood metagenomic next-generation sequencing (mNGS) in detecting pathogens from patients clinically diagnosed as acute hematogenous osteomyelitis (AHO).MethodsThis retrospective study enrolled 66 ...
Bingshi Zhang, Xiao Chen, Xiaowei Yao, Mengnan Li, Zhijie Li, Bo Liu, Sikai Liu, Zeming Liu, Jia Huo, Yongtai Han   +9 more
doaj   +1 more source

Clinical and radiologic outcomes in patients undergoing primary total hip arthroplasty with Collum Femoris Preserving stems: a comparison between the direct anterior approach and the posterior approach

BMC Musculoskeletal Disorders, 2022
Background The direct anterior approach (DAA) and posterior approach (PA) are two of the most common surgical approaches used for total hip arthroplasty (THA) worldwide.
Bingshi Zhang, Sikai Liu, Zeming Liu, Bo Liu, Jia Huo, Mengnan Li, Yongtai Han   +6 more
doaj   +1 more source

Risk Factors for Intraoperative Periprosthetic Femoral Fractures in Patients with Hip Dysplasia Undergoing Total Hip Arthroplasty with Uncemented Prostheses

Orthopaedic Surgery, 2021
Objectives To determine the potential risk factors for intraoperative periprosthetic femoral fractures in patients with developmental dysplasia of the hip (DDH) undergoing total hip arthroplasty (THA). Methods This was a retrospective study. Patients who
Bo Liu, Si‐kai Liu, Tao Wu, Ze‐ming Liu, Xiao Chen, Meng‐nan Li, Hui‐jie Li, Yong‐tai Han   +7 more
doaj   +1 more source

Diagnosis, preoperative evaluation, classification and total hip arthroplasty in patients with long-term unreduced hip joint dislocation, secondary osteoarthritis and pseudoarthrosis

BMC Musculoskeletal Disorders, 2020
Background Neglected long-term unreduced hip joint dislocation with secondary osteoarthritis and pseudoarthrosis poses a great challenge to hip surgeons. However, as this is an uncommon injury, few studies have systematically investigated these patients.
Bo Liu, Zhaoke Wu, Zhikun Zhuang, Sikai Liu, Huijie Li, Yongtai Han   +5 more
doaj   +1 more source

The indications for core decompression surgery in patients with ARCO stage I-II osteonecrosis of the femoral head: a new, comprehensive prediction system

BMC Musculoskeletal Disorders, 2023
Background Core decompression (CD) is considered the most popular treatment method for patients with Association Research Circulation Osseous (ARCO) stage I-II osteonecrosis of the femoral head (ONFH).
Congcong Wei, Meng Yang, Kun Chu, Jia Huo, Xiao Chen, Bo Liu, Huijie Li   +6 more
doaj   +1 more source

Extracellular Vesicles from BMSCs Prevent Glucocorticoid-Induced BMECs Injury by Regulating Autophagy via the PI3K/Akt/mTOR Pathway

Cells, 2022
Osteonecrosis of the femoral head (ONFH) is a common clinical disease with a high disability rate. Injury of bone microvascular endothelial cells (BMECs) caused by glucocorticoid administration is one of the important causes of ONFH, and there is ...
Jinhui Ma, Mengran Shen, Debo Yue, Weiguo Wang, Fuqiang Gao, Bailiang Wang   +5 more
doaj   +1 more source

Denosumab Can Prevent Collapse in Patients with Early‐Stage Steroid‐Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy

Orthopaedic Surgery, 2023
Objective The osteoclastic bone resorption inhibitors might have positive effect in preventing femoral head collapse in patients with osteonecrosis of the femoral head (ONFH).
Bo Liu, Feng Gao, Xiaofei Xiu, Tao Wu, Zeming Liu, Bingshi Zhang, Sikai Liu, Yongtai Han   +7 more
doaj   +1 more source