Results 31 to 40 of about 48,007 (294)

Radiographic sclerosis with intraoperative fragile bone in skeletal fluorosis: a case report

open access: yesFrontiers in Surgery
IntroductionSkeletal fluorosis is a rare toxic osteopathy characterized by massive bone fluoride fixation. The disease is an endemic problem in some parts of the world and is the result of the prolonged ingestion or inhalation of large amounts of ...
Weikun Hou   +4 more
doaj   +1 more source

Polymer Scaffolds-Enhanced Bone Regeneration in Osteonecrosis Therapy

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Osteonecrosis without effective early treatment eventually leads to the collapse of the articular surface and causes arthritis. For the early stages of osteonecrosis, core decompression combined with bone grafting, is a procedure worthy of attention and ...
Hengliang Dong   +7 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

Existing hip joint disease is associated with an increased incidence of hip fracture in adults: A retrospective survey of 9710 individuals from a single center

open access: yesHeliyon
Objective: In hip disease patients, pain and movement restrictions might cause changes in bone strength and increase the likelihood of falls, finally leading to hip fracture.
Bo Liu   +5 more
doaj   +1 more source

Medication-Related Osteonecrosis of the Jaws (MRONJ): Etiological Update

open access: yes, 2014
Osteonecrosis of the jaws (ONJ) is an uncommon but severe bone disease, can be related to various medicaments (MRONJ) including bisphosphonates (BRONJ), antiangiogenic and antiresorptive medicaments such as Denosumab (DRONJ), human monoclonal antibody to
TENORE, GIANLUCA   +13 more
core   +1 more source

Cell therapy for osteonecrosis of femoral head and joint preservation

open access: yes, 2021
Osteonecrosis of femoral head (ONFH) is a disease of the femoral head and can cause femoral head collapse and arthritis. This can lead to pain and gait disorders.
Won, Tae Gu   +11 more
core   +1 more source

A Novel Reactive Oxygen Species‐Responsive Bone‐Targeted Nanoplatform Based on Cloperastine Attenuates Ovariectomy‐Induced Bone Loss by Inhibiting Osteoclast Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
Cloperastine suppresses osteoclastogenesis by inhibiting PGC1β‐mediated oxidative phosphorylation. Its incorporation into a ROS‐responsive, Asp8‐modified nanoplatform enhances skeletal accumulation. The resulting Clo/Asp8‐PMK‐MCs combine cloperastine‐mediated antiresorptive activity with carrier‐mediated osteogenic activity to attenuate OVX‐induced ...
Haibo Liang   +16 more
wiley   +1 more source

Mn/Zn Bimetallic MOF‐Integrated Hydrogel Alleviates Excessive Mitochondrial Fission in BMSCs to Promote Osteoporotic Jawbone Repair

open access: yesAdvanced Science, EarlyView.
Excessive reactive oxygen species (ROS) and chronic inflammation impair bone marrow‐derived mesenchymal stem cells (BMSCs), contributing to poor healing in osteoporotic jawbone defect. The gelatin methacryloyl hydrogel loaded with manganese‐doped zeolitic imidazolate framework (Mn‐ZIF‐8@GelMA) promotes regeneration through redox regulation and ...
Xiayue Jin   +6 more
wiley   +1 more source

Atraumatic Osteonecrosis of the Humeral Head Associated with Pregnancy

open access: yes, 2010
Osteonecrosis is usually associated with trauma, the use of corticosteroids or alchohol abuse. Osteonecrosis associated with pregnancy has been reported previously and usually involves the femoral head.
Alan D. White   +2 more
core   +1 more source

Osteonecrosis of bilateral femoral head in a post COVID-19 patient: case report [PDF]

open access: yes, 2021
Osteonecrosis of the femoral head, can be secondary to various causes, which can be traumatic or atraumatic. The corticosteroid used is a common cause of non-traumatic osteonecrosis.
Chacko, Ankith   +5 more
core   +1 more source

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