Results 21 to 30 of about 42,834 (274)

Extracellular Vesicles from BMSCs Prevent Glucocorticoid-Induced BMECs Injury by Regulating Autophagy via the PI3K/Akt/mTOR Pathway

Cells, 2022
Osteonecrosis of the femoral head (ONFH) is a common clinical disease with a high disability rate. Injury of bone microvascular endothelial cells (BMECs) caused by glucocorticoid administration is one of the important causes of ONFH, and there is ...
Jinhui Ma, Mengran Shen, Debo Yue, Weiguo Wang, Fuqiang Gao, Bailiang Wang   +5 more
doaj   +1 more source

Denosumab Can Prevent Collapse in Patients with Early‐Stage Steroid‐Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy

Orthopaedic Surgery, 2023
Objective The osteoclastic bone resorption inhibitors might have positive effect in preventing femoral head collapse in patients with osteonecrosis of the femoral head (ONFH).
Bo Liu, Feng Gao, Xiaofei Xiu, Tao Wu, Zeming Liu, Bingshi Zhang, Sikai Liu, Yongtai Han   +7 more
doaj   +1 more source

Osteonecrosis of the Iliac Wing and Sacral Insufficiency Fractures After Radiotherapy: Case Presentation [PDF]

, 2021
Iliac wing osteonecrosis coexisting with sacral insufficiency fracture rarely causes low back pain. Radiotherapy (RT) applied to the pelvic area is an important precipitating factor.
Ezgi Yıldız Güvercin, Selbes, Esra Cansu, Esra Cansu Selbes, Cinar, Ece, Hepguler, Simin, Ece Çınar, Tamsel, Ipek, Guvercin, Ezgi Yildiz, Simin Hepgüler, İpek Tamsel   +9 more
core   +1 more source

As an unusual traumatic presentation, acetabular fracture and concomitant ipsilateral intertrochanteric femur fracture: a retrospective case series of 18 patients

Journal of Orthopaedic Surgery and Research, 2020
Background Acetabular fracture and concomitant ipsilateral intertrochanteric femur fracture has been suggested as an unusual traumatic presentation and rarely reported in the literature.
Bo Liu, Wenhui Ma, Sikai Liu, Xiao Chen, Mengnan Li, Jia Huo, Huijie Li, Yongtai Han   +7 more
doaj   +1 more source

High-energy focused extracorporeal shock wave prevents the occurrence of glucocorticoid-induced osteonecrosis of the femoral head: A prospective randomized controlled trial

Journal of Orthopaedic Translation, 2022
Background: Studies have shown that high-energy focused extracorporeal shock wave therapy (HF-ESWT) has a certain therapeutic effect on glucocorticoid-induced osteonecrosis of the femoral head (ONFH).
Xu Yang, Lijun Shi, Tao Zhang, Fuqiang Gao, Wei Sun, Peixu Wang, Xinjie Wu, Zirong Li   +7 more
doaj   +1 more source

Tibiofemoral rotation alignment in the normal knee joints among Chinese adults: a CT analysis

BMC Musculoskeletal Disorders, 2020
Background Consensus on tibial rotation in total knee arthroplasty (TKA) remains controversial. The present study aimed to investigate the closest anatomical reference to surgical epicondylar axis (SEA) among 10 tibial markers in Chinese adults.
Yufeng Lu, Xiaoyu Ren, Benyin Liu, Peng Xu, Yangquan Hao   +4 more
doaj   +1 more source

Alumina ceramic-on-highly cross- linked polyethylene bearing in cementless total hip arthroplasty in young patients with osteonecrosis of femoral head [PDF]

, 2018
Although total hip arthroplasties (THAs) have been extremely successful, survivorship of THAs in young patients with osteonecrosis of femoral head has been limited by aseptic loosening and osteolysis secondary to wear and particulate polyethylene debris [
김영후
core   +1 more source

Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis [PDF]

, 2010
Bisphosphonates are the leading drugs for the treatment of osteoporosis. In ­randomized controlled trials (RCTs), alendronate, risedronate, and zoledronate have shown to reduce the risk of vertebral, nonvertebral, and hip fractures, whereas RCTs with ...
Graham Russell, Cooper, Cyrus, Ebetino, F. Hal, Cooper, C, Russell, RG, Pazianas, Michael, Ebetino, FH, Russell, R. Graham G., Pazianas, M   +8 more
core   +1 more source

Medication-Related Osteonecrosis of the Jaws (MRONJ): Etiological Update [PDF]

, 2014
Osteonecrosis of the jaws (ONJ) is an uncommon but severe bone disease, can be related to various medicaments (MRONJ) including bisphosphonates (BRONJ), antiangiogenic and antiresorptive medicaments such as Denosumab (DRONJ), human monoclonal antibody to
TENORE, GIANLUCA, ROMEO, Umberto, GAIMARI, GIANFRANCO, Gianfranco Gaimari, Orlando Brugnoletti, Mohamed Mohsen, BRUGNOLETTI, Orlando, Gianluca Tenore, BOVE, Ercole, PALAIA, GASPARE, Lino Bove, Rossella Lo Giudice, Gaspare Palaia, Umberto Romeo   +13 more
core   +1 more source

Dose adductor canal block combined with local infiltration analgesia has a synergistic effect than adductor canal block alone in total knee arthroplasty: a meta-analysis and systematic review

Journal of Orthopaedic Surgery and Research, 2019
Background Both adductor canal block (ACB) and local infiltration analgesia (LIA) are effective procedures for postoperative pain control in total knee arthroplasty (TKA) without motor blockade.
Wei Zuo, Wanshou Guo, Jinhui Ma, Wei Cui
doaj   +1 more source