Treatment of osteonecrosis of the femoral head using autologous cultured osteoblasts: a case report [PDF]
Journal of Medical Case Reports, 2008 Introduction Osteonecrosis of the femoral head is a progressive disease that leads to femoral head collapse and osteoarthritis. Our goal in treating osteonecrosis is to preserve, not to replace, the femoral head.
Kim Seok-Jung +4 more
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Early results of surgery for femoroacetabular impingement in patients with osteonecrosis of femoral head [PDF]
SICOT-J, 2018 Purpose: Femoroacetabular impingement and its surgical treatment have not been described before in osteonecrosis of femoral head. We present here outcomes of 15 patients with femoroacetabular impingement secondary to osteonecrosis of femoral head.
Goyal Tarun
doaj +2 more sources
Recent advances of DNA methylation in osteonecrosis of the femoral head [PDF]
Frontiers in GeneticsDNA methylation, maintenance, and demethylation are essential for maintaining normal physiological functions. Recent studies have revealed that DNA methylation plays a crucial role in the progression of osteonecrosis of the femoral head.
Tingting Zhou +7 more
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Transcriptomic insights into nerve growth factor–associated appositional bone formation in the reparative zone in osteonecrosis of the femoral head [PDF]
Journal of Orthopaedic Surgery and ResearchBackground In osteonecrosis of the femoral head, appositional bone formation occurs in the reparative zone, where new trabeculae surround necrotic bone, leading to trabecular thickening. However, the underlying molecular mechanisms remain unclear.
Yusuke Ayabe +6 more
doaj +2 more sources
GDF11 alleviates glucocorticoid-induced osteonecrosis of the femoral head by regulating angiogenesis via the PI3K-AKT-eNOS pathway [PDF]
Communications BiologyGlucocorticoid-induced osteonecrosis of the femoral head is a joint dysfunction disease. Impaired local angiogenesis and reduced perfusion are early pathological features of glucocorticoid-induced osteonecrosis of the femoral head, resulting from ...
Zhicheng Liu +14 more
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Bone and muscle crosstalk in steroid-induced osteonecrosis of the femoral head: a four-axis pathophysiological framework. [PDF]
Front ImmunolYan Y +6 more
europepmc +2 more sources
Osteonecrosis of the Femoral Head
JAAOS: Global Research and Reviews, 2022 Osteonecrosis of the femoral head is a progressive and debilitating condition with a wide variety of etiologies including trauma, steroid use, and alcohol intake. Diagnosis and staging are based on imaging including MRI at any stage and plain radiography in more advanced lesions.
Gary George, Joseph M. Lane
openaire +3 more sources
Human Immunodeficiency Virus in the Focus of Bone Tissue Destruction in Patients With Aseptic Osteonecrosis of the Femoral Head: Two Case Reports [PDF]
Travmatologiâ i Ortopediâ Rossii, 2023 Background. Osteonecrosis of the femoral head is significantly more common in HIV-positive patients than in the general population. The etiology and pathogenesis of this process are not fully understood.
Evgeny O. Peretsmanas +4 more
doaj +1 more source
Updating Osteonecrosis of the Femoral Head
Hip & Pelvis, 2023 Osteonecrosis of the femoral head (ONFH), a condition characterized by the presence of a necrotic bone lesion in the femoral head, is caused by a disruption in the blood supply. Its occurrence is more common in young and middle-aged adults and it is the main reason for performance of total hip arthroplasty in this age group. Its incidence is increasing
Young-Seung Ko +5 more
openaire +2 more sources
Science Progress, 2023 Background: Cell therapy has been proposed as part of the therapeutic arsenal to assist bone formation and remodeling in the early stages of osteonecrosis of the femoral head.
Sergio Martínez-Álvarez +8 more
doaj +1 more source