Results 41 to 50 of about 42,834 (274)

Construction and validation of steroid-induced rabbit osteonecrosis model

MethodsX, 2022
Osteonecrosis is a common orthopedic disease in clinic, resulting in joint collapse if appropriate treatment is not given in time. The clinical usage of high-dose steroid is one of the common causes of osteonecrosis.
Tongtong Zhu, Mengyang Jiang, Mingran Zhang, Liguo Cui, Xiaoyu Yang, Xukai Wang, Guangyao Liu, Jianxun Ding, Xuesi Chen   +8 more
doaj   +1 more source

Intraosseous Squamous Cell Carcinoma Associated with Denosumab-Induced Osteonecrosis of the Jaw [PDF]

, 2021
Medication-related osteonecrosis of the jaw (MRONJ) has been associated with the use of different drugs administered in the treatment of malignant neoplasms or metastases and in antiresorptive therapies. Since 2010, denosumab, a monoclonal antibody whose
Carlos Navarro Cuéllar, Zamorano León, José Javier, Rodríguez Pérez, Irene, Bacián Martínez, Sandra, Navarro Vila, Carlos, Ignacio Navarro Cuéllar, Edurne Palacios Weiss, José Luis del Castillo Pardo de Vera, García-Hidalgo Alonso, María Isabel, Amo Fernández de Velasco, Álvaro del, Pujol Romanyá, Roser, Margarita Escrig de Teijeiro, Palacios Weiss, Edurne, Navarro Cuéllar, Carlos, Álvaro del Amo Fernández de Velasco, María Isabel García-Hidalgo Alonso, Sandra Bacián Martínez, José J. Zamorano-León, López Farre, Antonio José, Arturo Sánchez-Pérez, Roser Pujol Romanyá, Antonio López-Farré, Navarro Cuéllar, Ignacio, Escrig de Teijeiro, Margarita, Sánchez-Pérez, Arturo, Irene Rodríguez Pérez, Castillo Pardo de Vera, José Luis del, Carlos Navarro Vila   +27 more
core   +2 more sources

Dysbarism-related osteonecrosis : proceedings of a Symposium on Dysbaric Osteonecrosis : presented by the Marine Biomedical Institute, the University of Texas Medical Branch, Galveston, Texas, February 1972 [PDF]

Scientific editors, Edward L. Beckman, David H. Elliott ; vol. editor, Elizabeth Miremont Smith."Medical, legal, and economic aspects of dysbaric osteonecrosis are covered in this symposium. Topic include: osteonecrosis in compressed-air workers, divers,

core   +1 more source

iNOS expression and osteocyte apoptosis in idiopathic, non-\ud traumatic osteonecrosis [PDF]

, 2015
Background and purpose\ud \ud Non-traumatic osteonecrosis is a progressive disease with multiple etiologies. It affects younger individuals more and more, often leading to total hip arthroplasty.
Kalhor, Ali, Lu, Shifeier, Crawford, Ross, Xiao, Yin, Wang, Jun, Ni, Jiang-Dong   +5 more
core   +1 more source

Aseptic-avascular osteonecrosis: local “silent inflammation” in the jawbone and RANTES/CCL5 overexpression [PDF]

, 2017
Johann Lechner,1 Sabine Schuett,2 Volker von Baehr2 1Clinic for Integrative Dentistry, Munich, 2Department of Immunology and Allergology, Institute for Medical Diagnostics in MVZ GbR, Berlin, Germany Abstract: Of the definitions listed in the ...
Volker von Baehr, Lechner J, Sabine Schuett, Schuett S, Johann Lechner, von Baehr V   +5 more
core   +2 more sources

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

Advanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu, Zehui Lv, Xuejie Cai, Penghui Wei, Dengliang Wang, Zhao Wang, Ruoying Wang, Yingjie Wang, Xingdong Yang, Yixin Bian, Jiawei Xu, Xisheng Weng, Liangfeng Wei   +12 more
wiley   +1 more source

Uso da laserterapia na osteonecrose e osteorradionecrose dos maxilares [PDF]

, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.A osteonecrose dos maxilares (ONM) pode ser dividida em dois grandes grupos: Osteonecrose relacionada com medicamentos (ONMRM) e a Osteorradionecrose (ORN).
Silva, Gabriel Xavier da
core  

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Cuidados na avaliação e atendimento odontológico em pacientes usuários de bisfosfonatos: uma revisão de literatura. [PDF]

, 2012
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Os bisfosfonatos são análogos estruturais do pirofosfato, que apresentam elevada afinidade pelo tecido ósseo.
Dengo, Suhéllen Vicenzi
core  

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source