Results 61 to 70 of about 42,650 (280)

Aggravated bone density decline following symptomatic osteonecrosis in children with acute lymphoblastic leukemia

Haematologica, 2015
Osteonecrosis and decline of bone density are serious side effects during and after treatment of childhood acute lymphoblastic leukemia. It is unknown whether osteonecrosis and low bone density occur together in the same patients, or whether these two ...
Marissa A.H. den Hoed, Saskia M.F. Pluijm, Mariël L. te Winkel, Hester A. de Groot-Kruseman, Martha Fiocco, Peter Hoogerbrugge, Jan A. Leeuw, Marrie C.A. Bruin, Inge M. van der Sluis, Dorien Bresters, Maarten H. Lequin, Jan C. Roos, Anjo J.P. Veerman, Rob Pieters, Marry M. van den Heuvel-Eibrink   +14 more
doaj   +1 more source

Intraosseous Squamous Cell Carcinoma Associated with Denosumab-Induced Osteonecrosis of the Jaw

, 2021
Medication-related osteonecrosis of the jaw (MRONJ) has been associated with the use of different drugs administered in the treatment of malignant neoplasms or metastases and in antiresorptive therapies. Since 2010, denosumab, a monoclonal antibody whose
Carlos Navarro Cuéllar, Zamorano León, José Javier, Rodríguez Pérez, Irene, Bacián Martínez, Sandra, Navarro Vila, Carlos, Ignacio Navarro Cuéllar, Edurne Palacios Weiss, José Luis del Castillo Pardo de Vera, García-Hidalgo Alonso, María Isabel, Amo Fernández de Velasco, Álvaro del, Pujol Romanyá, Roser, Margarita Escrig de Teijeiro, Palacios Weiss, Edurne, Navarro Cuéllar, Carlos, Álvaro del Amo Fernández de Velasco, María Isabel García-Hidalgo Alonso, Sandra Bacián Martínez, José J. Zamorano-León, López Farre, Antonio José, Arturo Sánchez-Pérez, Roser Pujol Romanyá, Antonio López-Farré, Navarro Cuéllar, Ignacio, Escrig de Teijeiro, Margarita, Sánchez-Pérez, Arturo, Irene Rodríguez Pérez, Castillo Pardo de Vera, José Luis del, Carlos Navarro Vila   +27 more
core   +1 more source

Combined Therapy with Shock Wave and Retrograde Bone Marrow-Derived Cell Transplantation for Osteochondral Lesions of the Talus

Scientific Reports, 2017
Multiple treatment strategies have been developed for osteochondral lesions (OCLs) of the talus. The purpose of this retrospective study was to assess retrograde autologous bone marrow cell (BMC) transplantation via core drilling (CD) combined with ...
Fuqiang Gao, Na Chen, Wei Sun, Bailiang Wang, Zhencai Shi, Liming Cheng, Zirong Li, Wanshou Guo   +7 more
doaj   +1 more source

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

[Osteonecrosis of the knee].

Acta orthopaedica et traumatologica turcica, 2008
Osteonecrosis of the knee was first described by Ahlback in 1968. Today, it is classified as spontaneous and secondary osteonecrosis. Spontaneous osteonecrosis is typically seen with unilateral involvement in patients older than 60 years. Secondary osteonecrosis occurs in younger patients bilaterally and with multifocal involvement.
AKGUN, İsik, UNLU, Mehmet
openaire   +2 more sources

iNOS expression and osteocyte apoptosis in idiopathic, non-\ud traumatic osteonecrosis

, 2015
Background and purpose\ud \ud Non-traumatic osteonecrosis is a progressive disease with multiple etiologies. It affects younger individuals more and more, often leading to total hip arthroplasty.
Kalhor, Ali, Lu, Shifeier, Crawford, Ross, Xiao, Yin, Wang, Jun, Ni, Jiang-Dong   +5 more
core   +1 more source

Safety profile comparison of intra‐articular corticosteroids, hyaluronic acid, platelet‐rich plasma, and cell‐based injections for knee osteoarthritis: A systematic review and meta‐analysis by the ESSKA Orthobiologics Initiative

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim was to compare the safety profiles of corticosteroids (CS), hyaluronic acid (HA), blood‐derived products based on platelet concentrates (for simplicity indicated as PRP ‐ platelet‐rich plasma ‐ being PRP the most common product), and cell‐based therapies (namely products exploiting the therapeutic function of mesenchymal ...
Alessandro Bensa, Andrea Piano, Giacomo Arthur Fumagalli, Laura de Girolamo, Lior Laver, Jérémy Magalon, Mikel Sánchez, Thomas Tischer, Giuseppe Filardo   +8 more
wiley   +1 more source

Low Oxygen Tension Enhances Osteogenic Potential of Bone Marrow-Derived Mesenchymal Stem Cells with Osteonecrosis-Related Functional Impairment

Stem Cells International, 2015
Objective. Glucocorticoids can affect the function of bone marrow-derived mesenchymal stem cells (BMMSCs) adversely and merit the requirement for a strategy to correct this anomaly; we assessed the effect of low oxygen (2%) on BMMSCs from rabbits with ...
Lihong Fan, Ruiyu Liu, Jia Li, Zhibin Shi, Xiaoqian Dang, Kunzheng Wang   +5 more
doaj   +1 more source

Aseptic-avascular osteonecrosis: local “silent inflammation” in the jawbone and RANTES/CCL5 overexpression

, 2017
Johann Lechner,1 Sabine Schuett,2 Volker von Baehr2 1Clinic for Integrative Dentistry, Munich, 2Department of Immunology and Allergology, Institute for Medical Diagnostics in MVZ GbR, Berlin, Germany Abstract: Of the definitions listed in the ...
Volker von Baehr, Lechner J, Sabine Schuett, Schuett S, Johann Lechner, von Baehr V   +5 more
core   +1 more source

Collagen‐membrane‐covered matrix‐associated chondrocyte implantation improves safety over periosteum‐covered MACI for large knee cartilage defects: A real‐world data analysis in the registry study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This registry study aimed to evaluate the safety and effectiveness of collagen membrane‐covered matrix‐associated autologous chondrocyte implantation (cMACI) versus periosteum‐covered MACI (pMACI) for large knee cartilage defects (Outerbridge III–IV, ≥4 cm²) in the femorotibial and/or patellofemoral joints with a minimum 2‐year follow ...
Yuji Uchio, Ryosuke Kuroda, Yasuo Niki, Katsura Sugawara, Yasuyuki Ishibash   +4 more
wiley   +1 more source