Results 1 to 10 of about 4,051 (205)
Evaluation of <sup>161</sup>Tb-Labeled Diphosphonates as Potential Bone-Targeting Agents. [PDF]
Int J Mol SciTwo diphosphonates, etidronic acid (HEDP) and zoledronic acid (ZOL), were radiolabelled with 161Tb and evaluated as potential bone-targeting radiopharmaceuticals. Radiolabeling was performed at pH 7, achieving high radiolabeling yields (greater than 98%)
Sitarica P +9 more
europepmc +2 more sources
The Journal of Bone and Joint Surgery. British volume, 1973 1. The phosphonates are simple chemical compounds containing P-C-P bonds which are resistant to the action of naturally occurring phosphatases and pyrophosphatases.
Roger Smith, R. Graham, G. Russell
core +2 more sources
Incidental finding of bone tracer accumulation in gastrointestinal stromal tumor: Two case reports [PDF]
Radiology Case ReportsBone scintigraphy with technetium-labelled diphosphonates is widely used for evaluating skeletal pathology. However, extra-osseous uptake may also be encountered and can indicate underlying neoplastic processes.
Gary Ka Wai Chan, MBChB +3 more
doaj +2 more sources
Renal secretion of diphosphonates in rats
Kidney International, 1975 Renal secretion of diphosphonates in rats. Diphosphonates, characterized by a P—C—P bond, are relatively new experimental drugs used for the treatment of myositis ossificans, dental calculus, nephrolithiasis and Paget's disease.
Bonjour, Jean-Philippe +2 more
core +3 more sources
Clinical characteristics and prognosis of patients with chronic recurrent multifocal osteomyelitis based on cluster analysis: a 6-year cohort study [PDF]
Italian Journal of PediatricsBackground This multicenter study aimed to address the heterogeneity of chronic recurrent multifocal osteomyelitis (CRMO) by identifying clinical subtypes through cluster analysis, exploring clinical features, treatment approaches, and short-term ...
Tong Yue +15 more
doaj +2 more sources
Review and Update of the Risk Factors and Prevention of Antiresorptive-Related Osteonecrosis of the Jaw [PDF]
Endocrinology and Metabolism, 2021 Antiresorptive-related osteonecrosis of the jaw (ARONJ) is a rare but serious adverse event of bisphosphonate or denosumab administration; it is associated with severe pain and a deteriorated quality of life.
Ha Young Kim
doaj +1 more source
Molecular imaging techniques in patients with persistent spinal pain syndrome type 2 - a systematic review and meta-analysis [PDF]
EJNMMI ReportsBackground Persistent postoperative low back pain, including persistent spinal pain syndrome type 2 (PSPS-T2), is a global healthcare challenge that lacks objective phenotypic diagnostic criteria or validated biomarkers.
Lara S. Burmeister +4 more
doaj +2 more sources
Molecules, 2022 All the enantiomers of (1-amino-3-hydroxypropane-1,3-diyl)diphosphonic acid, newly design phosphonate analogues of 4-hydroxyglutamic acids, were obtained.
Liwia Lebelt +2 more
doaj +1 more source
Long-Term Treatment of Postmenopausal Osteoporosis [PDF]
Endocrinology and Metabolism, 2021 Osteoporosis is an incurable chronic condition, like heart disease, diabetes, or hypertension. A large gap currently exists in the primary prevention of fractures, and studies show that an estimated 80% to 90% of adults do not receive appropriate ...
Jacques P. Brown
doaj +1 more source