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Bone is continually being removed and replaced throughout life by the actions of osteoblasts (bone forming cells) and osteoclasts (bone resorbing cells).
Findlay, D. +3 more
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Bone resorption and bone metastasis risk
Breast cancer tumors have a tendency to metastasize to the bone. After development of a bone metastasis, the median survival time is 40 months. Currently, little is known about the modifiable risk factors for developing bone metastases in women diagnosed with breast cancer. One possible modifiable risk factor is increased bone resorption.
Katlynn M, Mathis +5 more
openaire +3 more sources
La résorption des tissus minéralisés comme l'os est accomplie par un type cellulaire unique : l'ostéoclaste. Cette cellule multinucléée a la capacité de dissoudre le minéral en abaissant le pH. Par la suite, la libération de certaines enzymes protéolytiques, en particulier la cathepsine K, entraîne la digestion de la matrice organique constituée ...
Vincent Everts +2 more
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Mechanisms of Bone Resorption in Periodontitis [PDF]
Alveolar bone loss is a hallmark of periodontitis progression and its prevention is a key clinical challenge in periodontal disease treatment. Bone destruction is mediated by the host immune and inflammatory response to the microbial challenge. However, the mechanisms by which the local immune response against periodontopathic bacteria disturbs the ...
Stefan A. Hienz +2 more
openaire +6 more sources
Bioassay-guided fractionation to isolate compounds of onion (Allium cepa L.) affecting bone resorption [PDF]
In this work a hydrophilic ethanolic extract of onion (Allium cepa L.) devoid of flavonoids was found to inhibit significantly bone resorption in vitro and in vivo, whereas the flavonoids, claimed to posses phytoestrogen-like properties, were devoid of ...
Wetli, Herbert Alexander
core +1 more source
SummaryOsteocyte lacunae were measured in normal rats and in rats in which periosteal hypertrophy had been induced at the adductor longus-pectineus insertion. Lacunae in the cortex beneath the periosteal hypertrophy were significantly larger than lacunae in the cortex of the opposite side of the femur from the hypertrophy.
J. F. Shea +3 more
openaire +2 more sources
Bone fractures after menopause [PDF]
Every year 30% of individuals above age 65 fall, and falls are the principal cause of bone fractures. To reduce fracture incidence requires both prevention of falls and maintenance of bone strength.PubMed searches were performed, for studies of the ...
Ralston, Stuart H. +43 more
core +1 more source
Bone resorption goes green [PDF]
In this issue of Cell, McDonald et al. show that giant multinucleated, bone-resorbing osteoclasts dissolve into smaller cells, termed "osteopmorhs," which re-form into osteoclasts at distal bone sites (McDonald et al., 2021). These findings overturn the long-standing premise that osteoclasts differentiate solely from hematopoietic precursors and ...
Jameel, Iqbal, Mone, Zaidi
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Short dental implants in the posterior region : the effect of platform-switching and a nanorough surface on peri-implant bone loss [PDF]
Korte implantaten (10 mm lengte), waarvoor meerdere redenen bestaan. In de eerste plaats heeft een kort implantaat minder oppervlak beschikbaar voor contact tussen bot en implantaat dan een langer implantaat met eenzelfde diameter.
Telleman, Gerdien +5 more
core +1 more source
Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]
Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Stenbeck, G +11 more
core +1 more source

