Results 1 to 10 of about 251,654 (302)
Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption - implications for osteoclast quality [PDF]
BMC Musculoskeletal Disorders, 2010 Background Normal osteoclasts resorb bone by secretion of acid and proteases. Recent studies of patients with loss of function mutations affecting either of these processes have indicated a divergence in osteoclastic phenotypes.
Leeming Diana J +6 more
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Bio-Protocol, 2014 The Bone resorption assay provides an easy to use protocol for quantitatively measuring in vitro osteoclast-mediated bone resorption. Osteoclasts can be seeded onto the bone slices and formation of resorption pits can be quantified via toluidinblue ...
Carina Scholtysek +2 more
doaj +2 more sources
Bone resorption goes green [PDF]
Cell, 2021 In this issue of Cell, McDonald et al. show that giant multinucleated, bone-resorbing osteoclasts dissolve into smaller cells, termed "osteopmorhs," which re-form into osteoclasts at distal bone sites (McDonald et al., 2021). These findings overturn the long-standing premise that osteoclasts differentiate solely from hematopoietic precursors and ...
Jameel, Iqbal, Mone, Zaidi
openaire +2 more sources
Relationship between the Height of Alveolar Bone Resorption and Sex and Age in Adolescents
Fayixue Zazhi, 2022 ObjectiveTo explore the relationship between the height of alveolar bone resorption and sex and age in the adolescent dentition.MethodsMulti-slice computed tomography （MSCT） was used to measure the height of alveolar bone resorption at labial, lingual ...
MA Jing-jing +7 more
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The Mechanism Switching the Osteoclast From Short to Long Duration Bone Resorption
Frontiers in Cell and Developmental Biology, 2021 The current models of osteoclastic bone resorption focus on immobile osteoclasts sitting on the bone surface and drilling a pit into the bone matrix.
Jean-Marie Delaisse +11 more
doaj +1 more source
Humeral bone resorption after reverse shoulder arthroplasty using uncemented stem
JSES International, 2020 Background: Humeral stem loosening has gained attention as it has been identified as a cause of revision surgery in reverse shoulder arthroplasty (RSA).
Kazuya Inoue, MD, PhD +9 more
doaj +1 more source
Effects of material properties of femoral hip components on bone remodeling [PDF]
, 1992 Bone loss around femoral hip stems is one of the problems threatening the long-term fixation of uncemented stems. Many believe that this phenomenon is caused by reduced stresses in the bone (stress shielding).
Grootenboer, H.J. +2 more
core +8 more sources
Control of bone resorption by semaphorin 4D is dependent on ovarian function. [PDF]
PLoS ONE, 2011 Osteoporosis is one of the most common bone pathologies, which are characterized by a decrease in bone mass. It is well established that bone mass, which results from a balanced bone formation and bone resorption, is regulated by many hormonal ...
Romain Dacquin +5 more
doaj +1 more source
Bone, 2022 La résorption des tissus minéralisés comme l'os est accomplie par un type cellulaire unique : l'ostéoclaste. Cette cellule multinucléée a la capacité de dissoudre le minéral en abaissant le pH. Par la suite, la libération de certaines enzymes protéolytiques, en particulier la cathepsine K, entraîne la digestion de la matrice organique constituée ...
Vincent Everts +2 more
openaire +4 more sources
Journal of Pharmacological Sciences, 2012 Nobiletin, a polymethoxy flavonoid (PMF), inhibits systemic bone resorption and maintains bone mass in estrogen-deficient ovariectomized mice. This study examined the antiinflammatory effects of PMFs, nobiletin, and tangeretin on lipopolysaccharide (LPS)-
Tsukasa Tominari +4 more
doaj +1 more source