Results 21 to 30 of about 156,692 (263)

Bone resorption goes green [PDF]

Cell, 2021
In this issue of Cell, McDonald et al. show that giant multinucleated, bone-resorbing osteoclasts dissolve into smaller cells, termed "osteopmorhs," which re-form into osteoclasts at distal bone sites (McDonald et al., 2021). These findings overturn the long-standing premise that osteoclasts differentiate solely from hematopoietic precursors and ...
Jameel, Iqbal, Mone, Zaidi
openaire   +2 more sources

Repair of microdamage in osteonal cortical bone adjacent to bone screw.

PLoS ONE, 2014
Up to date, little is known about the repair mode of microdamage in osteonal cortical bone resulting from bone screw implantation. In this study, self-tapping titanium cortical bone screws were inserted into the tibial diaphyses of 24 adult male rabbits.
Lei Wang, Tingjun Ye, Lianfu Deng, Jin Shao, Jin Qi, Qi Zhou, Li Wei, Shijing Qiu   +7 more
doaj   +1 more source

Nobiletin, a Polymethoxy Flavonoid, Suppresses Bone Resorption by Inhibiting NFκB-Dependent Prostaglandin E Synthesis in Osteoblasts and Prevents Bone Loss Due to Estrogen Deficiency

Journal of Pharmacological Sciences, 2011
Nobiletin, a polymethoxy flavonoid, prevents cancer and inflammation, but the roles of nobiletin in bone are unclear. We examined the effects of nobiletin on bone resorption in vitro and on bone mass in ovariectomized (OVX) mice in vivo.
Suguru Harada, Tsukasa Tominari, Chiho Matsumoto, Michiko Hirata, Morichika Takita, Masaki Inada, Chisato Miyaura   +6 more
doaj   +1 more source

ELMO1 Regulates RANKL-Stimulated Differentiation and Bone Resorption of Osteoclasts

Frontiers in Cell and Developmental Biology, 2021
Bone homeostasis is a metabolic balance between the new bone formation by osteoblasts and old bone resorption by osteoclasts. Excessive osteoclastic bone resorption results in low bone mass, which is the major cause of bone diseases such as rheumatoid ...
Xinyue Liang, Yafei Hou, Lijuan Han, Shuxiang Yu, Yunyun Zhang, Xiumei Cao, Jianshe Yan, Jianshe Yan   +7 more
doaj   +1 more source

The Role of Bone and Root Resorption on the Biomechanical Behavior of Mandibular Anterior Teeth Subjected to Orthodontic Forces: A Finite Element Approach

Biomedicines
Aims: This study was conducted to systematically evaluate the biomechanical impact of varying degrees of root and bone resorption resulting from periodontitis and orthodontic tooth movement (OTM) on the mandibular anterior teeth.
Jana Flatten, Thomasz Gedrange, Christoph Bourauel, Ludger Keilig, Anna Konermann   +4 more
doaj   +1 more source

Bone Resorption Assay

Bio-Protocol, 2014
The Bone resorption assay provides an easy to use protocol for quantitatively measuring in vitro osteoclast-mediated bone resorption. Osteoclasts can be seeded onto the bone slices and formation of resorption pits can be quantified via toluidinblue ...
Carina Scholtysek, Gerhard Krönke, Georg Schett   +2 more
doaj   +1 more source

P38 mitogen-activated protein kinase inhibitor, FR167653, inhibits parathyroid hormone related protein-induced osteoclastogenesis and bone resorption. [PDF]

PLoS ONE, 2011
p38 mitogen-activated protein kinase (MAPK) acts downstream in the signaling pathway that includes receptor activator of NF-κB (RANK), a powerful inducer of osteoclast formation and activation.
Huiren Tao, Mina Okamoto, Masataka Nishikawa, Hideki Yoshikawa, Akira Myoui   +4 more
doaj   +1 more source

Pharmacological Topics of Bone Metabolism: The Physiological Function of the Sympathetic Nervous System in Modulating Bone Resorption

Journal of Pharmacological Sciences, 2008
The vertebrate skeleton is richly innervated with adrenergic and peptidergic nerve terminals, and these play important roles in bone remodeling. Recent studies have generally shown that increased sympathetic nervous activity causes bone loss via an ...
Akifumi Togari, Michitsugu Arai
doaj   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Bone resorption in parathyroid carcinoma [PDF]

BMJ Case Reports, 2014
A man in his 30s with a history of end-stage renal disease (ESRD) and metastatic parathyroid carcinoma presented to the hospital with severe shortness of breath, hypercalcaemia and diffuse bone pain. Chest radiograph (figure 1A) demonstrated profound demineralisation, and the distal phalanges appeared abnormal (figure 1B) due to bony resorption ...
Negar, Naderi, Michael T, McCurdy, Robert M, Reed   +2 more
openaire   +2 more sources