Finite Element Analysis of Bone Resorption Around Dental Implant
Journal of Biomechanical Science and Engineering, 2009 Previously, a few models have been proposed to predict bone resorption process due to stress shielding in long bones such as proximal femur; however, there are almost no reports on finite element analysis of loss of marginal dental bone that is caused ...
Lihe QIAN +3 more
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Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]
, 2018 Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N. +3 more
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Governing equations of tissue modelling and remodelling: A unified generalised description of surface and bulk balance [PDF]
, 2016 Several biological tissues undergo changes in their geometry and in their bulk material properties by modelling and remodelling processes. Modelling synthesises tissue in some regions and removes tissue in others.
Buenzli, Pascal R.
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Sympathetic Innervation Regulates Osteocyte‐Mediated Cortical Bone Resorption during Lactation
Advanced Science, 2023 Bone undergoes constant remodeling by osteoclast bone resorption coupled with osteoblast bone formation at the bone surface. A third major cell type in the bone is osteocytes, which are embedded in the matrix, are well‐connected to the lacunar network ...
Qiaoyue Guo +9 more
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Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts [PDF]
, 2019 Despite recent progress in its treatment, Multiple Myeloma (MM) remains incurable and its associated bone disease persists even after complete remission.
Atkinson, Emily G. +7 more
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BMC Musculoskeletal Disorders, 2002 Background Avascular necrosis of bone (osteonecrosis) can cause structural failure and subsequent deformation, leading to joint dysfunction and pain. Structural failure is the result of resorption of necrotic bone during revascularization, before new ...
Aspenberg Per, Åstrand Jörgen
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Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption
eLife, 2021 Bone formation and resorption are typically coupled, such that the efficacy of anabolic osteoporosis treatments may be limited by bone destruction. The multi-kinase inhibitor YKL-05–099 potently inhibits salt inducible kinases (SIKs) and may represent a ...
Cheng-Chia Tang +25 more
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Resorption controls bone anabolism driven by PTH receptor signaling in osteocytes [PDF]
, 2013 The contribution of remodeling-based bone formation coupled to osteoclast activity versus modeling-based bone formation that occurs independently of resorption, to the anabolic effect of PTH remains unclear.
Allen, Matthew R. +7 more
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Factors associated with implant marginal bone resorption after implant restoration in elderly patients with severe periodontitis [PDF]
Xin yixueObjective To analyze the factors related to implant marginal bone resorption after implant restoration in elderly patients with severe periodontitis. Methods One hundred and ninety-five elderly patients with severe periodontitis who underwent implant ...
LI Yue, MA Yanru
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Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption [PDF]
, 2019 Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs)
Cha, Young-Nam +6 more
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