Results 41 to 50 of about 1,145,483 (297)

Pharmacological Topics of Bone Metabolism: The Physiological Function of the Sympathetic Nervous System in Modulating Bone Resorption

Journal of Pharmacological Sciences, 2008
The vertebrate skeleton is richly innervated with adrenergic and peptidergic nerve terminals, and these play important roles in bone remodeling. Recent studies have generally shown that increased sympathetic nervous activity causes bone loss via an ...
Akifumi Togari, Michitsugu Arai
doaj   +1 more source

Calcium carbonate-calcium phosphate mixed cement compositions for bone reconstruction [PDF]

, 2006
The feasibility of making calcium carbonate-calcium phosphate (CaCO3-CaP) mixed cements, comprising at least 40 % (w/w) CaCO3 in the dry powder ingredients, has been demonstrated.
Bareille, Reine, Combes, Christèle, Rey, Christian   +2 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

3D‐Printed Titanium Gyroid Scaffold Structure Integrated With Tough Hybrid Materials for Cartilage Replacement

Advanced Engineering Materials, EarlyView.
This study proposes a potential device design for joint cartilage replacement. Silica‐polytetrahydrofuran (SiO2‐PolyTHF) hybrids with customizable mechanical properties were developed to mimic the characteristics of a natural meniscus. These were synthesized through a two‐pot sol–gel hybrid process.
Yu‐Chien Lin, Gloria R. Young, Francesca Tallia, Reece N. Oosterbeek, Shaaz Ghouse, Edward Spiers, Nupur Kohli, Tom Briggs, Marc Masen, Siwei Li, Ren‐Jei Chung, Jonathan R. T. Jeffers, Julian R. Jones   +12 more
wiley   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

In vivo loading increases mechanical properties of scaffold by affecting bone formation and bone resorption rates [PDF]

, 2011
A successful bone tissue engineering strategy entails producing bone-scaffold construct with adequate mechanical properties. Apart from the mechanical properties of the scaffold itself, the forming bone inside the scaffold also adds to the strength of ...
Pioletti, Dominique, Müller, R., Roshan-Ghias, A., Gholam-Rezaee, Mehdi, Müller, Ralph, Floor M. Lambers, Lambers, F.M., Alireza Roshan-Ghias, Gholam-Rezaee, M., Pioletti, D.P., Ralph Müller, Dominique P. Pioletti, Mehdi Gholam-Rezaee, Roshan Ghias, Alireza, Lambers, Floor, Roshan-Ghias A, Müller R, Pioletti DP, Lambers FM, Gholam-Rezaee M   +19 more
core   +2 more sources

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Osteoclast biology in bone resorption: a review

STEMedicine, 2020
What we know about bone resorption has changed a lot in the last few decades. The osteoclast is the only cell to nibble and break down the bone, and in the formation and resorption of bone tissue, osteoclasts play an important role.
Chao Fu, Ruyi Shi
doaj   +1 more source

Bone mineral density and bone turnover in male master track and field athletes aged 40-64 [PDF]

, 2010
We evaluated areal bone mineral density (aBMD), bone mineral content (BMC), and markers of bone turnover in male competitive masters athletes representing different training profile in the past and at present, aged 40–64 (14 endurance runners, and 12 ...
Rittweger, Jörn, Straburzyńska-Migaj, Ewa, Nowak, Alicja, Kusy, Krzysztof, Straburzynksa-Lupa, Anna, Nowak, Alicija, Zielinski, Jacek, Felsenberg, Dieter, Straburzynksa-Migaj, Ewa, Straburzyńska-Lupa, Anna, Pilaczyńska-Szcześniak, Lucja, Pilaczynska-Sczesniak, Lucja, Karolkiewicz, Joanna, Łucja Pilaczyńska-Szcześniak, Anna Straburzyńska-Lupa, Jörn Rittweger, Joanna Karolkiewicz, Krzysztof Kusy, Jacek Zieliński, Dieter Felsenberg, Ewa Straburzyńska-Migaj, Alicja Nowak   +21 more
core   +1 more source