Results 51 to 60 of about 251,654 (302)
Advanced Functional Materials, EarlyView.We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu +7 more
wiley +1 more source
Biomaterial Investigations in Dentistry, 2022 Statement of the problem: Narrow implants have been recommended in high esthetic demand regions to ensure greater buccal bone thickness (BBT) and minimize soft-tissue recession due to insufficient bone support.
Ivan Onone Gialain +5 more
doaj +1 more source
A theory for bone resorption based on the local rupture of osteocytes cells connections: A finite element study [PDF]
, 2015 In this work, a bone damage resorption finite element model based on the disruption of the inhibitory signal transmitted between osteocytes cells in bone due to damage accumulation is developed and discussed. A strain-based stimulus function coupled to a
Abdessalem Chamekh +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
PLoS ONE, 2021 IntroductionImplant material is a more important factor for periprosthetic tibial bone resorption than implant design after total knee arthroplasty (TKA). The virtual perturbation study was planned to perform using single case of proximal tibia model. We
Hyung Jun Park +5 more
doaj +1 more source
Frontiers in Endocrinology, 2022 Osteoporosis is a bone metabolic disorder characterized by decreased bone density and deteriorated microstructure, which increases the risk of fractures.
Tian-Liang Ma +9 more
doaj +1 more source
A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
Advanced Healthcare Materials, EarlyView.An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
Biological and Pharmaceutical Bulletin, 2003 Genistein, a soybean-derived isoflavone, has been shown to suppress osteoclastic bone resorption. To clarify the mechanisms underlying this action, we investigated the effects of genistein on the differentiation, cytoskeleton and function in mice osteoclasts in vitro and bone metabolism in ovariectomized rats.Primary OCs were isolated from 3 week-old ...
Binbin, Li, Shifeng, Yu
openaire +3 more sources
Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates [PDF]
, 2017 The design of synthetic bone grafts to foster bone formation is a challenge in regenerative medicine. Understanding the interaction of bone substitutes with osteoclasts is essential, since osteoclasts not only drive a timely resorption of the biomaterial,
Avnet, Sofia +7 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones +14 more
wiley +1 more source