Results 1 to 10 of about 112,041 (166)
Biomimetics, 2023 The formation of bone in a bone defect is accomplished by osteoblasts, while the over activation of fibroblasts promotes fibrosis. However, it is not clear how the extracellular matrix stiffness of the bone-regeneration microenvironment affects the ...
Shenghan Gao +6 more
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Cell Death Discovery, 2022 We explored the potential activity of compound 16 (Cpd16), a novel small molecule Nrf2 activator, in hydrogen peroxide (H2O2)-stimulated osteoblasts. In the primary murine/human osteoblasts and MC3T3-E1 murine osteoblastic cells, Cpd16 treatment at micro-
Jing-wei Zhao +6 more
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Bone & Joint Research, 2022 Aims: Bone regeneration during treatment of staphylococcal bone infection is challenging due to the ability of Staphylococcus aureus to invade and persist within osteoblasts.
Francisca I. Alagboso +6 more
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Osteoblast biology: developmental origin and interactive nature of osteoblasts
, 2021 Bone formation occurs throughout life to support growth and bone remodeling in response to mechanical forces, metabolic needs, and tissue repair upon injury. The physiological requirement for continuous bone renewal to accommodate remodeling necessitates recruitment, proliferation, and differentiation of bone-forming osteoblasts to counteract the ...
van der Eerden, Bram C.J. +1 more
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Biosafety of 3D printed titanium alloy porous materials to osteoblast cell line MC3T3-E1 [PDF]
Jichu yixue yu linchuang, 2020 Objective To prepare 3D-printed porous materials of titanium alloy by electron beaming melting (EBM) and to confirm its biosafety to osteoblasts (OB). Methods Three topological structures of titanium alloy porous materials (2.0 mm, 2.25 mm and 2.5 mm ...
JING Li, SHI Wen, CAO Yu, LIU Rui-sai, LIU Lu, LI Jian-yu, LIU Hui
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Osteoblast-Osteoclast Communication and Bone Homeostasis
Cells, 2020 Bone remodeling is tightly regulated by a cross-talk between bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoblasts and osteoclasts communicate with each other to regulate cellular behavior, survival and differentiation through direct cell ...
Jung-Min Kim +4 more
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Journal of Pharmacological Sciences, 2009 We analyzed the expression of 5-HT2 receptors and proteins related to inactivation of 5-HT in primary cultures of mouse osteoblasts. The mRNA for the 5-HT2A receptor was detectable in anaplastic osteoblasts as well as in differentiated and matured ...
Takao Hirai +3 more
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Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment
Breast Cancer Research, 2020 Background Osteoclast activation is a hallmark of breast cancer-induced bone disease while little is known about the role of osteoblasts in this process.
Marie-Therese Haider +9 more
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Effects of Mechanical Stress Stimulation on Function and Expression Mechanism of Osteoblasts
Frontiers in Bioengineering and Biotechnology, 2022 Osteoclasts and osteoblasts play a major role in bone tissue homeostasis. The homeostasis and integrity of bone tissue are maintained by ensuring a balance between osteoclastic and osteogenic activities.
Pan Liu +11 more
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Biomedical Papers, 2015 Background: This study was aimed to investigate whether osteoblasts from diabetic patients have a promoting effect on osteogenesis of human umbilical cord mesenchymal stem cells (HUMSCs).
Ha Cheng-Zhi +9 more
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