Results 31 to 40 of about 136,319 (308)

Bone Cell Exosomes and Emerging Strategies in Bone Engineering

open access: yesBiomedicines, 2022
Bone tissue remodeling is a highly regulated process balancing bone formation and resorption through complex cellular crosstalk between resident bone and microenvironment cells.
Sanjana Vig, Maria Helena Fernandes
doaj   +1 more source

Spreading area and shape regulate apoptosis and differentiation of osteoblasts [PDF]

open access: yes, 2013
The in vivo observations have indicated that at the remodeling sites of bone, the spreading area or shape of preosteoblasts is confined by the mineralized matrix.
Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Inst Mech, Beijing 100190, Peoples R China.   +9 more
core   +1 more source

Metaplasia of Chondrocytes into Osteoblasts

open access: yesFolia Biologica, 2006
Hypertrophic chondrocytes, commonly considered as terminal cells responsible for apoptotic elimination in endochondral osteogenesis, have the potential to switch their metabolic role and enter osteoblastic differentiation, based on histochemical, immunohistochemical, biochemical and cytological analysis.
Krzysztof H, Włodarski   +2 more
openaire   +2 more sources

Increased local bone turnover in patients with chronic periprosthetic joint infection

open access: yesBone & Joint Research, 2023
Aims: The management of periprosthetic joint infection (PJI) remains a major challenge in orthopaedic surgery. In this study, we aimed to characterize the local bone microstructure and metabolism in a clinical cohort of patients with chronic PJI ...
Nico Hinz   +7 more
doaj   +1 more source

Research Progress of Paradoxical Bone Formation in Osteoporosis [PDF]

open access: yesZhongguo quanke yixue
Osteoporosis is a common clinical bone disease caused by a variety of causes, it increases osteoclast production mainly by changing the inflammatory microenvironment of the body, the end result is increased bone resorption and decreased bone mass ...
YANG Yang, GAO Xi
doaj   +1 more source

Coumarin Ameliorates Impaired Bone Turnover by Inhibiting the Formation of Advanced Glycation End Products in Diabetic Osteoblasts and Osteoclasts

open access: yesBiomolecules, 2020
Accumulating evidence demonstrates that the risk of osteoporotic fractures increases in patients with diabetes mellitus. Thus, diabetes-induced bone fragility has recently been recognized as a diabetic complication. As the fracture risk is independent of
Eun-Jung Lee   +8 more
doaj   +1 more source

MicroRNA-21: An Emerging Player in Bone Diseases

open access: yesFrontiers in Pharmacology, 2021
MicroRNAs (MiRNAs) are small endogenous non-coding RNAs that bind to the 3′-untranslated region of target genes and promote their degradation or inhibit translation, thereby regulating gene expression. MiRNAs are ubiquitous in biology and are involved in
Chen Chen   +6 more
doaj   +1 more source

Acid-Induced Inflammatory Cytokines in Osteoblasts: A Guided Path to Osteolysis in Bone Metastasis

open access: yesFrontiers in Cell and Developmental Biology, 2021
Bone metastasis (BM) is a dismal complication of cancer that frequently occurs in patients with advanced carcinomas and that often manifests as an osteolytic lesion.
Gemma Di Pompo   +9 more
doaj   +1 more source

Oxidative stress-induced apoptotic insults to rat osteoblasts are attenuated by nitric oxide pretreatment via GATA-5-involved regulation of Bcl-X (L) gene expression and protein translocation

open access: yes, 2017
Nitric oxide (NO) has biphasic effects on regulating osteoblast survival and death. This study was aimed to evaluate the effects of NO pretreatment on hydrogen peroxide (HP)-induced insults of rat osteoblasts and the possible mechanisms.
劉興華   +1 more
core   +1 more source

Analysis of the Intrinsic Self-Organising Properties of Mesenchymal Stromal Cells in Three-Dimensional Co-Culture Models with Endothelial Cells

open access: yesBioengineering, 2018
Mesenchymal stem/stromal cells (MSCs) are typically characterised by their ability to differentiate into skeletal (osteogenic, chondrogenic and adipogenic) lineages.
Julia Marshall   +2 more
doaj   +1 more source

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