Results 1 to 10 of about 38,017 (252)

miR-452-3p inhibited osteoblast differentiation by targeting Smad4 [PDF]

open access: yesPeerJ, 2021
Osteoblast differentiation is a complex process that is essential for normal bone formation. A growing number of studies have shown that microRNAs (miRNAs) are key regulators in a variety of physiological and pathological processes, including ...
Ming Wu   +6 more
doaj   +2 more sources

SLC38A2 provides proline and alanine to regulate postnatal bone mass accrual in mice

open access: yesFrontiers in Physiology, 2022
Amino acids have recently emerged as important regulators of osteoblast differentiation and bone formation. Osteoblasts require a continuous supply of amino acids to sustain biomass production to fuel cell proliferation, osteoblast differentiation and ...
Leyao Shen   +4 more
doaj   +1 more source

Constitutive activation of Gli2 impairs bone formation in postnatal growing mice. [PDF]

open access: yesPLoS ONE, 2013
Indian hedgehog (Ihh) signaling is indispensable for osteoblast differentiation during endochondral bone development in the mouse embryo.
Kyu Sang Joeng, Fanxin Long
doaj   +1 more source

Probiotic Propionibacterium freudenreichii MJ2 Enhances Osteoblast Differentiation and Mineralization by Increasing the OPG/RANKL Ratio

open access: yesMicroorganisms, 2021
Osteoblast differentiation is important for the development of bone and the maintenance of bone density. Propionibacterium freudenreichii is a probiotic with an anti-inflammatory property.
Jiah Yeom, Seongho Ma, Young-Hee Lim
doaj   +1 more source

BMP-2 Induced Expression of Alx3 That Is a Positive Regulator of Osteoblast Differentiation. [PDF]

open access: yesPLoS ONE, 2013
Bone morphogenetic proteins (BMPs) regulate many aspects of skeletal development, including osteoblast and chondrocyte differentiation, cartilage and bone formation, and cranial and limb development.
Takashi Matsumoto   +10 more
doaj   +1 more source

From osteoblast to osteoclast: new insights of Yin-Yang theory in bone remodeling

open access: yesWorld Journal of Traditional Chinese Medicine, 2015
Yin-Yang theory plays critical role in traditional Chinese medicine (TCM) science. However, there are many competing interpretations of Yin-Yang theory in the context with the development in biology, and no consensus has been established.
Dong-Feng Zhao   +7 more
doaj   +1 more source

Core-binding factor beta is required for osteoblast differentiation during fibula fracture healing

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background Growing evidence has implicated core-binding factor beta (Cbfb) as a contributor to osteoblast differentiation, which plays a key role in fracture healing. Herein, we aimed to assess whether Cbfb affects osteoblast differentiation after fibula
Tuanmao Guo   +6 more
doaj   +1 more source

Osteoblast biology: developmental origin and interactive nature of osteoblasts

open access: yes, 2021
Bone formation occurs throughout life to support growth and bone remodeling in response to mechanical forces, metabolic needs, and tissue repair upon injury. The physiological requirement for continuous bone renewal to accommodate remodeling necessitates recruitment, proliferation, and differentiation of bone-forming osteoblasts to counteract the ...
van der Eerden, Bram C.J.   +1 more
openaire   +1 more source

Regulation of osteoblast differentiation mediated by BMP, Notch, and CCN3/NOV

open access: yesJapanese Dental Science Review, 2008
Osteoblasts originate from common progenitors, which are capable of differentiating into other mesenchymal cell lineages such as chondrocytes, myoblasts and adipocytes.
Akira Yamaguchi   +4 more
doaj   +1 more source

Cell Transitions Contribute to Glucocorticoid-Induced Bone Loss

open access: yesCells, 2023
Glucocorticoid-induced bone loss is a toxic effect of long-term therapy with glucocorticoids resulting in a significant increase in the risk of fracture.
Xiaojing Qiao   +10 more
doaj   +1 more source

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