Results 11 to 20 of about 115,464 (311)

From osteoblast to osteoclast: new insights of Yin-Yang theory in bone remodeling

World Journal of Traditional Chinese Medicine, 2015
Yin-Yang theory plays critical role in traditional Chinese medicine (TCM) science. However, there are many competing interpretations of Yin-Yang theory in the context with the development in biology, and no consensus has been established.
Dong-Feng Zhao, Cheng-Long Wang, Yong-Jian Zhao, Zhi-Lie Yang, Qi Shi, Xu Feng, Yan-Ping Yang, Yong-Jun Wang   +7 more
doaj   +1 more source

Regulation of osteoblast differentiation mediated by BMP, Notch, and CCN3/NOV

Japanese Dental Science Review, 2008
Osteoblasts originate from common progenitors, which are capable of differentiating into other mesenchymal cell lineages such as chondrocytes, myoblasts and adipocytes.
Akira Yamaguchi, Kei Sakamoto, Tokutarou Minamizato, Kenichi Katsube, Shoichi Nakanishi   +4 more
doaj   +1 more source

Cell Transitions Contribute to Glucocorticoid-Induced Bone Loss

Cells, 2023
Glucocorticoid-induced bone loss is a toxic effect of long-term therapy with glucocorticoids resulting in a significant increase in the risk of fracture.
Xiaojing Qiao, Xiuju Wu, Yan Zhao, Yang Yang, Li Zhang, Xinjiang Cai, Jocelyn A. Ma, Jaden Ji, Karen Lyons, Kristina I. Boström, Yucheng Yao   +10 more
doaj   +1 more source

Resveratrol Attenuates High Glucose-Induced Osteoblast Dysfunction via AKT/GSK3β/FYN-Mediated NRF2 Activation

Frontiers in Pharmacology, 2022
Osteoblast dysfunction, induced by high glucose (HG), negatively impacts bone homeostasis and contributes to the pathology of diabetic osteoporosis (DOP).
Yue Xuan, Jie Wang, Xiaohui Zhang, Jie Wang, Jiahao Li, Qingbo Liu, Guangping Lu, Mengjie Xiao, Ting Gao, Yuanfang Guo, Cong Cao, Ou Chen, Kunli Wang, Yufeng Tang, Junlian Gu   +14 more
doaj   +1 more source

Osteoblast-Targeting-Peptide Modified Nanoparticle for siRNA/microRNA Delivery [PDF]

, 2016
Antiosteoporosis gene-based drug development strategies are presently focused on targeting osteoblasts to either suppress bone loss or increase bone mass.
Xiangning Liu (431172), An Hong (2747227), Xiongzhen Ye (2747224), Bin Zhang (64682), Yayu Wang (1658227), Jia Xiao (553000), Jiafan Liu (2747230), Xiaogang Wang (250803), Mingxiang Cai (282695), Zuolin Wang (2747233), Yao Sun (145327), Chen Kang (1416142), Chenyang Zhang (1383045), Li Yang (6520), Qi Zhang (28502), Shannai Li (2747236)   +15 more
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Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo [PDF]

, 2008
Resident macrophages are an integral component of many tissues and are important in homeostasis and repair. This study examines the contribution of resident tissue macrophages to bone physiology.
Chang, M. K., Kuliwaba, J., Fazzalari, N., Maylin, E., Raggatt, Liza-Jane, Kuliwaba, Julia S., Alexander, K., Hume, D., Schroder, Kate, Maylin, Erin R., Alexander, Kylie A., Maylin, E. R., Fazzalari, Nicola L., Raggatt, L. J., Ripoll, V., Alexander, K. A., Ripoll, V. M., Schroder, K., Ripoll, Vera M, Pettit, A., Raggatt, L., Pettit, Allison R., Kuliwaba, J. S., Fazzalari, N. L., Hume, D. A., Hume, David A., Pettit, A. R., Chang, M., Chang, Ming K.   +28 more
core   +1 more source

PPAR Gamma Activity and Control of Bone Mass in Skeletal Unloading

PPAR Research, 2006
Bone loss occuring with unloading is associated with decreased osteoblastogenesis and increased bone marrow adipogenesis, resulting in bone loss and decreased bone formation.
P. J. Marie, K. Kaabeche
doaj   +1 more source

Repression of osteoblast maturation by ERRα accounts for bone loss induced by estrogen deficiency. [PDF]

PLoS ONE, 2013
ERRα is an orphan member of the nuclear receptor family, the complete inactivation of which confers resistance to bone loss induced by ageing and estrogen withdrawal to female mice in correlation with increased bone formation in vivo.
Marlène Gallet, Soraya Saïdi, Eric Haÿ, Johann Photsavang, Caroline Marty, Juliette Sailland, Julie Carnesecchi, Violaine Tribollet, Bruno Barenton, Christelle Forcet, Marie-Christine Birling, Tania Sorg, Olivier Chassande, Martine Cohen-Solal, Jean-Marc Vanacker   +14 more
doaj   +1 more source

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice [PDF]

, 2010
Nearly every extracellular ligand that has been found to play a role in regulating bone biology acts, at least in part, through MAPK pathways. Nevertheless, much remains to be learned about the contribution of MAPKs to osteoblast biology in vivo. Here we
Zhai, Bo, Weiguo Zou, Shim, Jae-Hyuck, Hu, Dorothy, Lotinun, Sutada, Glimcher, Laurie H., Arthur, Simon; id_orcid, Michael D. Schneider, Yasuyo Sano, Min Xie, Matthew B. Greenblatt, Laurie H. Glimcher, Jae-Hyuck Shim, Roger Davis, Xie, Min, Sano, Yasuyo, Despina Sitara, Schweitzer, Michelle, Park, Jin Mo, Schneider, Michael D., Gygi, Steven, Greenblatt, Matthew B., Baron, Roland, Simon Arthur, Zou, Weiguo, Jin Mo Park, Michelle Schweitzer, Davis, Roger, Roland Baron, Sitara, Despina, Sutada Lotinun, Dorothy Hu, Bo Zhai, Steven Gygi   +33 more
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Metaplasia of Chondrocytes into Osteoblasts

Folia Biologica, 2006
Hypertrophic chondrocytes, commonly considered as terminal cells responsible for apoptotic elimination in endochondral osteogenesis, have the potential to switch their metabolic role and enter osteoblastic differentiation, based on histochemical, immunohistochemical, biochemical and cytological analysis.
Krzysztof H, Włodarski, Paweł K, Włodarski, Aniela, Brodzikowska   +2 more
openaire   +2 more sources