Results 31 to 40 of about 128,752 (251)

Different titanium surfaces influence in vitro the biological behavior of SaOS-2 human osteoblast-like cells. [PDF]

open access: yes, 2009
Osseointegrated dental implants have been successfully used over the past several years, allowing functional replacement of missing teeth. Surface properties of titanium dental implants seem to affect bone cell response.
Capece, Gabriele
core   +1 more source

Improved Protocol to Study Osteoblast and Adipocyte Differentiation Balance [PDF]

open access: yes, 2022
Adipogenesis-osteoblastogenesis balance-rupture is relevant in multiple diseases. Current human mesenchymal stem cells (hMSCs) in vitro differentiation models are expensive, and are hardly reproducible.
María Guillán-Fresco   +17 more
core   +1 more source

TMEM175 plays a crucial role in osteoblast differentiation by regulating lysosomal function and autophagy

open access: yesMolecules and Cells
: Bone provides structural support, enables movement, protects internal organs, regulates calcium and phosphorus levels, and contains bone marrow essential for hematopoiesis.
Seung Hye Lee   +3 more
doaj   +1 more source

Identification of genes involved in osteoblast differentiation with an shRNA-based approach [PDF]

open access: yes, 2009
Mesenchymal stem cells (MSCs) derived from bone marrow and they can differentiate in a variety of cell types, including osteoblasts, adipocytes, chondrocytes, myoblasts, hepatocytes, and neural cells.
Cozzolino, Carmine
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

FXR Activation Accelerates Early Phase of Osteoblast Differentiation Through COX-2-PGE2-EP4 Axis in BMP-2-Induced Mouse Mesenchymal Stem Cells

open access: yesMolecules
Farnesoid X receptor (FXR), a nuclear receptor, is expressed in calvaria and bone marrow stromal cells and plays a role in bone homeostasis. However, the mechanism of FXR-activated osteoblast differentiation remains unclear.
Ko Fujimori   +4 more
doaj   +1 more source

Osteoblast origins and occurrences.

open access: yes, 2021
Osteoblast origins and occurrences.
Bregje W. M. de Wildt (11648899)   +6 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The effect of application of bovine amniotic membrane on osteoblasts, osteocytes, and collagen in the post-extraction alveolar bone socket of Sprague Dawley rats

open access: yesPadjadjaran Journal of Dentistry, 2023
Introduction: Tooth extraction can result in loss of alveolar bone. The application of biomaterials Bovine Amniotic Membrane (BAM) that containing growth factors and collagen is expected to play a role in socket preservation.
Artdhea Regita Wibowo   +3 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

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