Results 51 to 60 of about 128,752 (251)

Legumain is a paracrine regulator of osteoblast differentiation and mediates the inhibitory effect of TGF-β1 on osteoblast maturation

open access: yesFrontiers in Endocrinology
Transforming growth factor-beta 1 (TGF-β1) is a critical regulator of skeletal homeostasis and has diverse effects on osteoblastogenesis. To date, the mechanisms behind the intriguing inhibitory effect of TGF-β1 on osteoblast maturation are not fully ...
Karl Martin Forbord   +5 more
doaj   +1 more source

Graphene Layers as Functional Biomaterials. From Fabrication and Characterization to Biological Applications

open access: yesAdvanced Materials Interfaces, EarlyView.
Graphene layers are fabricated on Cu foil and transferred onto glass substrates to form double‐ and multi‐layer G‐glass. Raman spectroscopy confirms structural integrity, while SEM and fluorescence microscopy reveal favorable adhesion and spreading of L‐929 fibroblast cells.
Mariana Mihaela Apostol   +8 more
wiley   +1 more source

Osteoblast Number in Tension Area by Giving Propolis Extract As Orthodontic Relaps Prevention

open access: yesDenta, 2021
Background: relapse is often happen after orthodontic treatment finished. Propolis contains flavonoid, saponin and CAPE that known increase the number of osteoblast. Osteoblast have important role in bone remodeling which can prevent relapse.
Budi Handayani, Arya Brahmanta
doaj  

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani   +2 more
wiley   +1 more source

Neddylation of NFATc1 and Runx2 regulates osteoclast–osteoblast balance and represents a dual-action therapeutic target for postmenopausal osteoporosis

open access: yesExperimental and Molecular Medicine
Postmenopausal osteoporosis (PMOP) arises from a bone remodeling imbalance in which osteoclast-mediated resorption exceeds osteoblast-driven formation.
Jooseung Lee   +8 more
doaj   +1 more source

Expression and functional role of nitric oxide synthase isoforms in human osteoblast-like cells

open access: yes, 1999
Previous studies have shown evidence of constitutive and cytokine-inducible nitric oxide (NO) synthase activity in cultured osteoblast-like cells from various species.
B.S. Noble, S.H. Ralston, H. MacPherson
core   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

sEV-mediated lipid droplets transferred from bone marrow adipocytes promote ferroptosis and impair osteoblast function

open access: yesJournal of Lipid Research
Osteoporosis is linked to increased bone marrow adipocyte (BMAd) proliferation, which displaces bone-forming cells and alters the local environment. The impact of BMAd lipid droplets on bone health and osteoblast function remains unclear.
Weibo Huang   +5 more
doaj   +1 more source

Osteoblast - 3

open access: yes, 2010
An image from a bone marrow showing an osteoblast (labeled)
Fraser, Marion
core   +1 more source

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