Results 1 to 10 of about 4,668,187 (354)
Basic problems for the construction of a scenario for the Life are discussed. To study the problems in terms of dynamical systems theory, a scheme of intra-inter dynamics is presented.
Kaneko K. +7 more
core +2 more sources
Background The proliferation and adipogenic differentiation of adipose stromal cells (ASCs) are complex processes comprising major phenotypical alterations driven by up- and downregulation of hundreds of genes.
Claudia Krautgasser +5 more
doaj +1 more source
Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. [PDF]
Viral oncoproteins that inactivate the retinoblastoma tumor suppressor protein (pRb) family both block skeletal muscle differentiation and promote cell cycle progression.
Jacks, T +3 more
core
Osteoclast Differentiation [PDF]
The osteoclast is the primary bone resorbing cell. It is a highly specialized multinucleated cell whose primary function is to help in the control of calcium homeostasis. The osteoclast has been very difficult to study because of its relative inaccessability, low numbers, and fragility when isolated from bone.
openaire +2 more sources
To develop a culture system for large-scale production of mature hepatocytes, liver progenitor cells (LPCs) with a high proliferation potential would be advantageous.
Taketomo Kido +7 more
doaj +1 more source
Automatic Differentiation Variational Inference
Probabilistic modeling is iterative. A scientist posits a simple model, fits it to her data, refines it according to her analysis, and repeats. However, fitting complex models to large data is a bottleneck in this process.
Blei, David M. +4 more
core
Fréchet differentiability via partial Fréchet differentiability
Let $X_1, \dots, X_n$ be Banach spaces and $f$ a real function on $X=X_1 \times\dots \times X_n$. Let $A_f$ be the set of all points $x \in X$ at which $f$ is partially Fr\' echet differentiable but is not Fr\' echet differentiable. Our results imply that if $X_1, \dots, X_{n-1}$ are Asplund spaces and $f$ is continuous (resp.
openaire +3 more sources
Multi‐layered stochasticity and paracrine signal propagation shape the type‐I interferon response
The cellular recognition of viruses evokes the secretion of type‐I interferons (IFNs) that induce an antiviral protective state. By live‐cell imaging, we show that key steps of virus‐induced signal transduction, IFN‐β expression, and induction of IFN ...
Ulfert Rand +10 more
doaj +1 more source
Xbra modulates the activity of linker region phosphorylated Smad1 during Xenopus development
The Bmp/Smad1 pathway plays a crucial role in developmental processes and tissue homeostasis. Mitogen-activated protein kinase (Mapk)/Erk mediated phosphorylation of Smad1 in the linker region leads to Smad1 degradation, cytoplasmic retention and ...
Santosh Kumar +6 more
doaj +1 more source

