Results 31 to 40 of about 4,094,095 (307)

Program differentiation [PDF]

open access: yesProceedings of the 2010 Workshop on Interaction between Compilers and Computer Architecture, 2010
Mobile electronics are undergoing a convergence of what were formerly multiple single application devices into a single programmable device — generally a smart phone. The programmability of these devices increases their vulnerability to malicious attack.
Daniel Chang   +4 more
openaire   +1 more source

Scheduling and Quality Differentiation in Differentiated Services [PDF]

open access: yes, 2003
This paper provides insight into the problems and possibilities related to quality differentiation, traffic mapping and scheduling in Differentiated Services. We focus on the differentiation of two important quality parameters, capacity and delay, and consider two models in detail: absolute capacity differentiation and proportional delay ...
Johanna Antila, Marko Luoma
openaire   +1 more source

The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse

open access: yesScientific Reports, 2018
The transcription factor C/EBPβ regulates hematopoiesis, bone, liver, fat, and skin homeostasis, and female reproduction. C/EBPβ protein expression from its single transcript occurs by alternative in-frame translation initiation at consecutive start ...
Valérie Bégay   +4 more
doaj   +1 more source

NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation

open access: yesNature Communications, 2021
Mitotic spindle assembly is required for proper cell division, but many underlying mechanisms remain unclear. Here, the authors show that NuMa undergoes liquid-liquid phase separation, condensing on spindle poles during mitotic entry and enriching ...
Mengjie Sun   +7 more
doaj   +1 more source

MicroRNAs Modulate Hematopoietic Lineage Differentiation

open access: yesScience, 2004
MicroRNAs (miRNAs) are an abundant class of ∼22-nucleotide regulatory RNAs found in plants and animals. Some miRNAs of plants, Caenorhabditis elegans, and Drosophila play important gene-regulatory roles during development by pairing to target mRNAs to ...
Chang-Zheng Chen   +3 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Regulatory T Cells: Mechanisms of Differentiation and Function

open access: yesAnnual Review of Immunology, 2012
The immune system has evolved to mount an effective defense against pathogens and to minimize deleterious immune-mediated inflammation caused by commensal microorganisms, immune responses against self and environmental antigens, and metabolic ...
Steven Z. Josefowicz   +2 more
semanticscholar   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging

open access: yesNature Communications, 2018
Cellular senescence is associated with epigenetic remodeling. Here, the authors report that TGF-β signaling promotes miR-29 mediated loss of H4K20me3 thus accelerating senescence.
Guoliang Lyu   +10 more
doaj   +1 more source

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