Results 21 to 30 of about 1,901,215 (265)
Analyze p53 degradation by 35S p53 Pulse Chase Analysis
Bio-Protocol, 2012 p53, is known as the guardian of the genome and as such requires exquisite regulation not only of its abundance but also its activity. The abundance of p53 can be modulated at the level of transcription, translation, and also via its degradation.This ...
Megan Astle +2 more
doaj +1 more source
Nature Communications, 2022 Limited response to immune checkpoint inhibitors has been reported in patients with castration-resistant prostate cancer. Here the authors show that intermittent, but not continuous, treatment with an anti-PI3Kα/β/δ-inhibitor promotes anti-tumor immunity
Zhi Qi +8 more
doaj +1 more source
Generation of High Quality Memory B Cells
Frontiers in Immunology, 2022 Protection against pathogen re-infection is mediated, in large part, by two humoral cellular compartments, namely, long-lived plasma cells and memory B cells.
Takeshi Inoue +4 more
doaj +1 more source
Differentiating the differential rotation effect
Acta Psychologica, 2012 As an observer views a picture from different viewing angles, objects in the picture appear to maintain their orientation relative to the observer. For instance, the eyes of a portrait appear to follow the observer as he or she views the image from different angles. We have explored this rotation effect, often called the Mona Lisa effect.
Evgenia, Boyarskaya, Heiko, Hecht
openaire +2 more sources
Proceedings of the 5th international conference on Computer graphics and interactive techniques in Australia and Southeast Asia, 2007 A number of popular global illumination algorithms uses density estimation to approximate indirect illumination. The density estimate is performed on finite points -- particles -- generated by a stochastic sampling of the scene. In the course of the sampling, particles, representing light, are stochastically emitted from the light sources and reflected
Lars Schjøth +3 more
openaire +3 more sources
Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease
BMC Genomics, 2018 Background Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth.
Guoliang Lyu +11 more
doaj +1 more source
Proceedings of the 2010 Workshop on Interaction between Compilers and Computer Architecture, 2010 Mobile electronics are undergoing a convergence of what were formerly multiple single application devices into a single programmable device — generally a smart phone. The programmability of these devices increases their vulnerability to malicious attack.
Daniel Chang +4 more
openaire +1 more source
The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse
Scientific Reports, 2018 The transcription factor C/EBPβ regulates hematopoiesis, bone, liver, fat, and skin homeostasis, and female reproduction. C/EBPβ protein expression from its single transcript occurs by alternative in-frame translation initiation at consecutive start ...
Valérie Bégay +4 more
doaj +1 more source
NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation
Nature Communications, 2021 Mitotic spindle assembly is required for proper cell division, but many underlying mechanisms remain unclear. Here, the authors show that NuMa undergoes liquid-liquid phase separation, condensing on spindle poles during mitotic entry and enriching ...
Mengjie Sun +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele +19 more
wiley +1 more source