Results 21 to 30 of about 4,668,187 (354)

Machine learning identifies phenotypic profile alterations of human dopaminergic neurons exposed to bisphenols and perfluoroalkyls

open access: yesScientific Reports, 2023
Parkinson’s disease (PD) is the second most common neurodegenerative disease and is characterized by the loss of midbrain dopaminergic neurons. Endocrine disrupting chemicals (EDCs) are active substances that interfere with hormonal signaling. Among EDCs,
Andrea Di Credico   +6 more
doaj   +1 more source

Terminal differentiation of adult hippocampal progenitor cells is a step functionally dissociable from proliferation and is controlled by Tis21, Id3 and NeuroD2 [PDF]

open access: yes, 2017
Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Daniele Saraulli   +9 more
core   +2 more sources

Differential Assessment, Differential Benefit [PDF]

open access: yesProceedings of the Seventh ACM Conference on Learning @ Scale, 2020
Using five million responses to thousands of practice examination questions on an optional study service known as Problem Roulette, we explore subject-specific differences in assessment style, grade benefit from usage of the service, and differential features in study behavior and grade outcome by birth sex. Our study includes more than 20,000 students
Noah Weaverdyck   +2 more
openaire   +1 more source

Rapid generation of secondary fibroblasts through teratoma formation

open access: yesBioTechniques, 2015
The use of secondary or reprogrammable cells in the production of induced pluripotent stem cells (iPSCs) circumvents random infection by various viral particles and random, uncontrollable integrations of the viral genomes into different genomic loci.
Sang Mi Cho   +4 more
doaj   +1 more source

The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. [PDF]

open access: yes, 2018
Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs).
Li, Shengwen Calvin   +6 more
core   +2 more sources

Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification

open access: yesCancer Biology & Therapy, 2023
The possible anticancer activity of combination (M + E + F) of metformin (M), efavirenz (E), and fluoxetine (F) was investigated in normal HDF cells and HCT116 human colon cancer cells.
Beom-Goo Kang   +13 more
doaj   +1 more source

Differentiation of Differentiation

open access: yesSSRN Electronic Journal, 2012
Increased global competitiveness, reduced product life cycles, rapid technological advancements, and dynamic customer requirements have drastically altered the nature of competition. Researchers and entrepreneurs have different ways how to achieve competitive advantages.
Valentina Ivannii, Lara Jelenc
openaire   +3 more sources

Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]

open access: yes, 2015
We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana   +2 more
core   +4 more sources

Efficient definitive endoderm induction from mouse embryonic stem cell adherent cultures: A rapid screening model for differentiation studies

open access: yesStem Cell Research, 2014
Definitive endoderm (DE) differentiation from mouse embryonic stem cell (mESC) monolayer cultures has been limited by poor cell survival or low efficiency.
Josué Kunjom Mfopou   +6 more
doaj   +1 more source

Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions

open access: yesJournal of Translational Medicine, 2016
Background In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other “classic” sources have been described. However, the phenotypic and functional properties of tumor MSCs are poorly understood.
María de Lourdes Mora-García   +10 more
doaj   +1 more source

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