Results 11 to 20 of about 4,668,187 (354)

Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence

open access: yesCanadian Respiratory Journal, 2022
Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading
Lan Wang   +7 more
doaj   +1 more source

DIFFERENTIAL GEOMETRY FROM DIFFERENTIAL EQUATIONS [PDF]

open access: yesThe Ninth Marcel Grossmann Meeting, 2001
37 pages, revised version with ...
Frittelli, Simonetta   +2 more
openaire   +2 more sources

Overview of CircRNAs Roles and Mechanisms in Liver Fibrosis

open access: yesBiomolecules, 2023
Liver fibrosis represents the reversible pathological process with the feature of the over-accumulation of extracellular matrix (ECM) proteins within the liver, which results in the deposition of fibrotic tissues and liver dysfunction. Circular noncoding
Gaiping Wang   +6 more
doaj   +1 more source

Point-Substitution of Phenylalanine Residues of 26RFa Neuropeptide: A Structure-Activity Relationship Study

open access: yesMolecules, 2021
26RFa is a neuropeptide that activates the rhodopsin-like G protein-coupled receptor QRFPR/GPR103. This peptidergic system is involved in the regulation of a wide array of physiological processes including feeding behavior and glucose homeostasis. Herein,
Benjamin Lefranc   +12 more
doaj   +1 more source

Cryo-derived plants through embryogenesis showed same levels of vinblastine and vincristine (anticancer) in Catharanthus roseus and had normal genome size

open access: yesScientific Reports, 2022
Cryopreservation of rare plant materials is an important approach for preserving germplasms and is a good added concept to tissue banking. The preservation of embryogenic cell suspensions is even more valuable as the tissues facilitate in producing ...
A. Mujib   +2 more
doaj   +1 more source

Mitochondrial Dysfunction and Chronic Liver Disease

open access: yesCurrent Issues in Molecular Biology, 2022
Mitochondria are generally considered the powerhouse of the cell, a small subcellular organelle that produces most of the cellular energy in the form of adenosine triphosphate (ATP). In addition, mitochondria are involved in various biological functions,
Chunyan Zhang   +5 more
doaj   +1 more source

Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos

open access: yesAnimal Cells and Systems, 2020
Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this ...
Zobia Umair   +9 more
doaj   +1 more source

DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy

open access: yesGenetics and Molecular Biology, 2014
Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration.
Deming Li   +3 more
doaj   +1 more source

N-Acetylcysteine Reduces the Pro-Oxidant and Inflammatory Responses during Pancreatitis and Pancreas Tumorigenesis

open access: yesAntioxidants, 2021
Pancreatitis, an inflammation of the pancreas, appears to be a main driver of pancreatic cancer when combined with Kras mutations. In this context, the exact redox mechanisms are not clearly elucidated.
Marie-Albane Minati   +4 more
doaj   +1 more source

Delayed Liver Regeneration after Partial Hepatectomy in Aged Nos2 Knockout Mice

open access: yesCell Journal, 2017
Objective Patients over 60 years of age have higher mortality and morbidity after major liver resections. Nitric oxide (NO) derived from the catalytic activity of Nos2 plays a beneficial role in liver regeneration (LR) after partial hepatectomy (PH). In
Deming Li   +6 more
doaj   +1 more source

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