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Osteoprotegerin in diabetic osteopathy
Nutrition, Metabolism and Cardiovascular Diseases, 2020The aim of this study is to evaluate the relationship between OPG and the degree of glycaemic control in a population of elderly subjects.Data presented included 172 elderly subjects, of whom 107 were hospitalized for a hip fracture and 65 were non fractured outpatients.
Massimo Federici +2 more
exaly +4 more sources
Osteoprotegerin as a marker of atherosclerosis: A systematic update
Scandinavian Cardiovascular Journal, 2012Osteoprotegerin (OPG) may be involved in development of atherosclerosis. To evaluate plasma concentrations of OPG in individuals with stable coronary artery disease (CAD), acute coronary syndrome (ACS), peripheral artery disease (PAD), and cerebrovascular disease (CBVD) a systematic literature review was performed.Studies investigating OPG ...
Tina Svenstrup Poulsen +2 more
exaly +3 more sources
The effect of osteoprotegerin nanocomplex on osteoprotegerin and arteriosclerosis in mice
Materials Express, 2023Osteoprotegerin (OPG), as one of the tumor necrosis factor receptors, is believed to be related with Osteoprotegerin (OP) and arteriosclerosis (AS). This study aims to explore the effect of OPG on osteoblasts (OB) and AS. The nanocomplex Poly(ethylene glycol)-Poly(L-Lysine)-Osteoprotegerin (PPO) was prepared by introducing OPG plasmid to Poly(ethylene ...
Zhiwen He, Shuang Wang, Xiaoxuan Xia
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Ortopedia, traumatologia, rehabilitacja, 2012
In 1997, a glycoprotein was isolated that blocked osteoclast differentiation from precursor cells. This protein prevented osteoporosis when administered to ovariectomized rats, and led to osteopetrosis when overexpressed. This newly discovered protein was named osteoprotegerin (OPG).
Marleen A. Baak +15 more
openaire +3 more sources
In 1997, a glycoprotein was isolated that blocked osteoclast differentiation from precursor cells. This protein prevented osteoporosis when administered to ovariectomized rats, and led to osteopetrosis when overexpressed. This newly discovered protein was named osteoprotegerin (OPG).
Marleen A. Baak +15 more
openaire +3 more sources
Osteoprotegerin and Diabetic Macroangiopathy
Hormone and Metabolic Research, 2005Osteoprotegerin (OPG) is a bone-related protein that is also present in the vasculature. Recent data suggest that it may play a special role in arterial disease among patients with diabetes. Diabetic macroangiopathy is characterized by a series of diffuse, non-atherosclerotic alterations that hypothetically increase the vulnerability of the vessel wall
L M, Rasmussen, T, Ledet
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Serum levels of osteoprotegerin and osteoprotegerin polymorphisms in Gaucher disease
British Journal of Haematology, 2006SummaryBone involvement in Gaucher disease causes disability and reduced quality of life; loss of function and pain are important indications for enzyme replacement therapy. The purpose of this study was to ascertain whether osteoprotegerin (OPG), which decreases osteoclast activity, is indicative of incipient bone involvement by comparing OPG serum ...
Itai, Magal +7 more
openaire +2 more sources
Osteoprotegerin and kidney disease
Journal of Nephrology, 2014Vascular calcification in chronic kidney disease (CKD) patients is associated to increased mortality. Osteoprotegerin (OPG) is a soluble tumor necrosis factor (TNF) superfamily receptor that inhibits the actions of the cytokines receptor activator of nuclear factor kappa-B ligand (RANKL) and TNF-related apoptosis-inducing ligand (TRAIL) by preventing ...
Alejandra, Montañez-Barragán +5 more
openaire +2 more sources
Role for osteoprotegerin in rheumatoid inflammation
Joint Bone Spine, 2004Osteoprotegerin (OPG), a member of the TNF-receptor family expressed by osteoblasts, has documented effects on the regulation of bone metabolism. OPG inhibits bone resorption and binds with strong affinity to its ligand RANKL, thereby preventing RANKL from binding to its receptor RANK. This system is regulated by calcium-modifying hormones.
Nathalie, Saidenberg-Kermanac'h +4 more
openaire +2 more sources
Osteoprotegerin and Diabetes-Associated Pathologies
Current Molecular Medicine, 2011Osteoprotegerin (OPG) is a member of the tumour necrosis factor receptor superfamily of cytokines which, in spite of being initially described as a strong anti-resorptive factor, has lately been considered as a possible link between bone and vascular disease.
A M, Blázquez-Medela +2 more
openaire +2 more sources

