Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin‐Deficient Mice [PDF]
Background The biological mechanism of action for osteoprotegerin, a soluble decoy receptor for the receptor activator of nuclear factor‐kappa B ligand in the vascular structure, has not been elucidated.
Toshihiro Tsuruda +12 more
doaj +2 more sources
Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders [PDF]
The relationship between osteoprotegerin, RANKL and interleukin-17 inthe mechanisms of abnormal remodeling of bone tissue during experimental periodontitis was studied in this work. Increased levels of RANKL and pro-inflammatory IL-17 were found, as well
V. F. Cheremisina
doaj +5 more sources
Serum Osteoprotegerin Level Is Not a Localizing Biomarker of Atherosclerosis Affected by Kidney Function [PDF]
Introduction: Osteoprotegerin (OPG) is recognized as an emerging biomarker for atherosclerosis. We hypothesized that atherosclerotic lesions localized across multiple vascular beds would result in greater elevations in OPG levels in the blood. Therefore,
Anna Maria Bednarek +4 more
doaj +2 more sources
Serum Osteoprotegerin Is Associated Independently with Peripheral Arterial Stiffness in Chronic Kidney Disease [PDF]
Background/Objectives: Patients with chronic kidney disease (CKD) often present with peripheral arterial stiffness (PAS), which is associated with an increased cardiovascular risk.
Yahn-Bor Chern +5 more
doaj +2 more sources
Association between serum osteoprotegerin level and renal prognosis in nondialysis patients with chronic kidney disease in the Korean Cohort Study for Outcomes in Patients with Chronic Kidney Disease (the KNOW-CKD Study) [PDF]
Background Osteoprotegerin is an important regulator of bone metabolism and vascular calcification. The association between serum osteoprotegerin level and chronic kidney disease (CKD) progression has not been elucidated.
Tae Ryom Oh +11 more
doaj +1 more source
Objective To investigate the effect of sequential Helicobacter pylori eradication therapy on serum osteoprotegerin levels in patients with H. pylori infection and co-existing inflammatory bowel disease (IBD).
Hussam Murad +4 more
doaj +1 more source
BackgroundChronic kidney disease has emerged as a significant independent risk factor for cardiovascular disease. Cardiovascular calcification is an active process involving a complex interaction of inducers and inhibitors.
Kamal M. Okasha +17 more
doaj +1 more source
Osteoprotegerin in Cardiometabolic Disorders [PDF]
Osteoprotegerin (OPG), a glycoprotein traditionally implicated in bone remodelling, has been recently related to cardiovascular disease (CVD). Human studies show a positive relationship between circulating OPG, vascular damage, and CVD, and as such OPG has emerged as a potential biomarker for CVD.
Pérez de Ciriza, C. +2 more
openaire +5 more sources
SYNOVIAL AND SERUM LEVELS OF OSTEOCALCIN, OSTEOPROTEGERIN AND Β-CROSSLAPS IN PATIENTS WITH CALCIUM PYROPHOSPHATE DEPOSITION DISEASE [PDF]
Background. Calcium pyrophosphate deposition disease is defined by deposition of calcium pyrophosphate crystals in hyaline cartilage, fibrocartilage and soft tissues. The study of bone markers is of great interest in different types of arthritis.
Paulina Vele +5 more
doaj +1 more source
Background Decreased extracellular matrix formation and few vascular smooth muscle cells (VSMCs) in cerebral vascular walls are the main characteristics of intracranial aneurysm (IA) pathogenesis.
Takeshi Miyata +8 more
doaj +1 more source

