Results 31 to 40 of about 39,213 (240)
Medicina, 2022 Background and Objectives: Atherosclerosis is a disease in the pathogenesis of which plasma factors apart from elevated cholesterol levels play a keyrole. Such factors include osteopontin (OPN), osteoprotegerin (OPG), and metalloproteinases (MMPs), which
Michał Kosowski +3 more
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Changes in PGE2 signaling after submandibulectomy alter post–tooth extraction socket healing [PDF]
, 2018 Saliva is very important to oral health, and a salivary deficit has been shown to bring serious problems to oral health. There is scant information about the mechanisms through which salivary glands participate in post–tooth extraction socket healing ...
Bozzini, Clarisa +5 more
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Osteoprotegerin, vascular calcification and atherosclerosis [PDF]
Atherosclerosis, 2009 The association of bone pathologies with atherosclerosis has stimulated the search for common mediators linking the skeletal and the vascular system. Since its initial discovery as a key regulator in bone metabolism, osteoprotegerin (OPG) has become the subject of intense interest for its role in vascular disease and calcification. Studies in vitro and
Golledge, Jonathan, Van Campenhout, Ann
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Relationship between serum osteoprotegerin and vascular calcifications in hemodialysis patients
The Egyptian Heart Journal, 2017 Background: Uremia is a vasculopathic process, and both cardiac calcification and vascular calcification seen from the early stages of chronic kidney disease.
Tarek Z. El Baz +5 more
doaj +1 more source
Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle [PDF]
, 2017 The estimates of global incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) are worrisome, due to the parallel burden of obesity and its metabolic complications. Indeed, excess adiposity and insulin resistance represent two of the major
Chiesa, Claudio +4 more
core +2 more sources
Osteoprotegerin Protects against Muscular Dystrophy [PDF]
The American Journal of Pathology, 2015 Receptor-activator of NF-κB, its ligand RANKL, and the soluble decoy receptor osteoprotegerin are the key regulators of osteoclast differentiation and bone remodeling. Although there is a strong association between osteoporosis and skeletal muscle atrophy/dysfunction, the functional relevance of a particular biological pathway that synchronously ...
Sébastien S, Dufresne +5 more
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Frontiers in Cardiovascular Medicine, 2019 The physicochemical deposition of calcium-phosphate in the arterial wall is prevented by calcification inhibitors. Studies in cohorts of patients with rare genetic diseases have shed light on the consequences of loss-of-function mutations for different ...
Magnus Bäck +18 more
doaj +1 more source
Biomedicines, 2023 Background: The ossification of the posterior longitudinal ligament (OPLL) is one of the contributing factors leading to severe cervical spondylotic myelopathy (CSM). The mechanism causing ossification is still unclear.
Li-Yu Fay +15 more
doaj +1 more source
Strontium ranelate effect on bone mineral density is modified by previous bisphosphonate treatment [PDF]
, 2014 The aim of this study was to evaluate the effect of strontium ranelate (SrR) on bone mineral density (BMD) and boneturnover markers after 1 year of treatment.
Brance, María Lorena +13 more
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Therapeutic implications of osteoprotegerin
Cancer Cell International, 2009 Osteoprotegerin (OPG), a member of the tumor necrosis factor (TNF) receptor superfamily, contributes determinatively to the bone remodeling as well as to the pathogenetic mechanism of bone malignancies and disorders of mineral metabolism. There is additional evidence that OPG can promote cell survival by inhibiting TNF-related apoptosis-inducing ligand
Fili, S., Karalaki, M., Schaller, B.
openaire +4 more sources