Results 51 to 60 of about 20,163 (204)

Association of periodontitis with serum osteoprotegerin level in type 2 diabetic postmenopausal women

Journal of the Pakistan Medical Association
Objective: To evaluate the association of periodontitis with serum osteoprotegerin level according to glycaemic state in postmenopausal type 2 diabetic women.
Dalia Kudier Abbas, Abdulkareem Hamady Issa   +1 more
doaj   +1 more source

Circulating levels of osteoprotegerin and sRANKL and the effect of methotrexate in patients with rheumatoid arthritis

Indian Journal of Rheumatology, 2018
Background: Receptor activator of nuclear factor κβ ligand (RANKL) and osteoprotegerin (OPG) are pivotal molecules involved in osteoclast activation and resorption.
Aadhaar Dhooria, Narendhiran Pandurangan, Karthik Vinay Mahesh, Suchet Sachdev, Aman Sharma, Shefali Sharma, Nidhi Gupta, Varun Dhir   +7 more
doaj   +1 more source

Osteoprotegerin, vascular calcification and atherosclerosis [PDF]

Atherosclerosis, 2009
The association of bone pathologies with atherosclerosis has stimulated the search for common mediators linking the skeletal and the vascular system. Since its initial discovery as a key regulator in bone metabolism, osteoprotegerin (OPG) has become the subject of intense interest for its role in vascular disease and calcification. Studies in vitro and
Golledge, Jonathan, Van Campenhout, Ann
openaire   +3 more sources

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, EarlyView.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source

Effect of anatomical location (mandible vs maxilla) of dental implants on the BMP-2, BMP-7, sRANKL and OPG levels in periimplant crevicular fluid during osseointegration. A pilot study

Selcuk Dental Journal, 2019
Background:The aim of this study was to investigate levels of bone morphogenetic protein-2 (BMP-2), BMP-7, soluble receptor activator of nuclear factor-kB ligand (sRANKL) and osteoprotegerin (OPG) in the peri-implant crevicular fluid (PICF) of  implants ...
Mehmet Sağlam, Doğan Dolanmaz, Emrah Koçak, Burcu Poyraz, Özgür İnan, Niyazi Dündar, Sema Hakkı   +6 more
doaj   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

Journal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis, Kelly Galisteu‐Luiz, Gabriela Leite Pedroso, Gustavo Lopes Puls, Leticia Cassaro, Bruno Boaventura Vieira, Fábio Lourenço Romano, Erika Calvano Küchler, Christian Kirschneck, Daniela Silva Barroso de Oliveira, Maria Bernadete Sasso Stuani, Mirian Aiko Nakane Matsumoto   +11 more
wiley   +1 more source

Prognostic Value of Serum Osteoprotegerin Level in Patients With Hepatocellular Carcinoma Following Surgical Resection

Frontiers in Oncology, 2021
BackgroundMultiple studies have reported that tissue or serum osteoprotegerin (OPG) level is a prognostic factor for patients with cancer. However, little is known about the role of serum OPG in hepatocellular carcinoma (HCC).
Chihao Zhang, Jiayun Lin, Xiaochun Ni, Hongjie Li, Lei Zheng, Zhifeng Zhao, Xiaoliang Qi, Haizhong Huo, Xiaolou Lou, Qiang Fan, Meng Luo   +10 more
doaj   +1 more source

Serum osteoprotegerin and renal osteodystrophy [PDF]

Nephrology Dialysis Transplantation, 2002
Numerous growth factors and cytokines are known to modulate bone turnover. An important, recently discovered complex involved in osteoclastogenesis is the osteoprotegerin/osteoprotegerin-ligand (OPG/OPGL) cytokine complex, which is produced by osteoblasts.
Coen, Giorgio, Ballanti, Paola, Balducci, Alessandro, Calabria, Santo, Fischer, Maria Stephanie, Jankovic, Ljiljana, Manni, Micaela, Morosetti, Massimo, Moscaritolo, Eleonora, Sardella, Daniela, Bonucci, Ermanno   +10 more
openaire   +3 more sources

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Identification of Predictable Biomarkers in Conjunction to Framingham Risk Score to Predict the Risk for Cardiovascular disease (CVD) in Non Cardiac Subjects [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Although the cardiovascular disease (CVD) burden is rising in different countries, the morbidity and mortality rate is not reduced to much extent because of lack of application of the biomarkers for diagnosing CVD.
Rama Krishna Reddy Y.V., Jaideep Mahendra, Prema Gurumurthy, Jayamathi, Sai Babu   +4 more
doaj   +1 more source