Results 51 to 60 of about 25,487 (238)

OSM counteracts the effect of RCCS on the RANKL: osteoprotegerin ratio. [PDF]

, 2015
Semi-quantitative RT-PCR was used to examine the interaction of OSM and modeled microgravity on the osteoblast transcription of MCSF, RANKL, and osteoprotegerin.
Ken Tawara (748035), Julia Thom Oxford (748038), Danielle Hedeen (748036), Cheryl L. Jorcyk (748039), Jake Goyden (748034), Jeffrey S. Willey (748037)   +5 more
core   +1 more source

Differential expression of receptor activator of nuclear factor-?B ligand and osteoprotegerin mRNA in periodontal diseases [PDF]

, 2007
Background and Objective: Receptor activator of nuclear factor-?B ligand (RANKL) is responsible for the induction of osteoclastogenesis and bone resorption, whereas its decoy receptor, osteoprotegerin, can directly block this action. Because this dyad of
Han B., Belibasakis G.N., Ilgenli T., Afacan B., Bostanci N., Töz H., Atilla G., Hughes F.J., McKay I.J., Emingil G., Berdeli A.   +10 more
core   +3 more sources

Value of serum osteoprotegerin in the assessment of endothelial dysfunction in obesity

The Egyptian Journal of Internal Medicine
Objective Osteoprotegerin is a member of the tumor necrosis factor receptor superfamily. The study aimed to assess serum osteoprotegerin and endothelial dysfunction relationship in obese non-diabetic subjects.
Ahmed Mohammed Shennawy, Hany William Z. Hanna, Salma Raed, Randa Salam, Sama Ayman   +4 more
doaj   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

FEATURES OF STEROID REGULATION OF CONGENITAL PROTECTIVE FACTORS AND OSTEOTROPIC MEDIATORS OF ORAL FLUID IN PREGNANT WOMEN WITH INFLAMMATORY PERIODONTAL DISEASES

Кубанский научный медицинский вестник, 2018
Aim. To study changes in antimicrobial and osteotropic oral fluid mediators during pregnancy in women with chronic generalized periodontitis (CGР) of mild and moderate severity, taking into account the factor of steroid regulation by cortisol.Materials ...
V. A. PROHODNAJA, S. O. SURMENEVA, E. H. CHIBICHJAN, Y. V. BOLOCKIKH, A. A. OVSYANNIKOVA   +4 more
doaj   +1 more source

Comparative Study of the Cytokine Profiles of Serum and Tissues from Patients with the Ossification of the Posterior Longitudinal Ligament

Biomedicines, 2023
Background: The ossification of the posterior longitudinal ligament (OPLL) is one of the contributing factors leading to severe cervical spondylotic myelopathy (CSM). The mechanism causing ossification is still unclear.
Li-Yu Fay, Chao-Hung Kuo, Hsuan-Kan Chang, Mei-Yin Yeh, Chih-Chang Chang, Chin-Chu Ko, Tsung-Hsi Tu, Yi-Hsuan Kuo, Wang-Yu Hsu, Chien-Hui Hung, Ching-Jung Chen, Jau-Ching Wu, May-Jywan Tsai, Wen-Cheng Huang, Henrich Cheng, Meng-Jen Lee   +15 more
doaj   +1 more source

Association of osteoprotegerin with peripheral artery disease in patients with type 2 diabetes [PDF]

, 2015
SummaryBackgroundOsteoprotegerin plays a critical role in the pathogenesis of atherosclerosis. Elevated osteoprotegerin concentrations have been reported in microvascular complications of diabetes.
Noshad, Sina, Rad, Mona Vahidi, Nakhjavani, Manouchehr, Esteghamati, Alireza, Mazaheri, Tina, Aflatoonian, Maryam, Mousavizadeh, Mostafa   +6 more
core   +1 more source

Osteoprotegerin modulates platelet adhesion to von Willebrand factor during release from endothelial cells [PDF]

, 2022
Background Platelet-binding Von Willebrand Factor (VWF) strings assemble upon stimulated secretion from endothelial cells. Objectives To investigate the efficiency of platelet binding to multi-molecular VWF bundles secreted from endothelial cells and to ...
Wohner, N., Lenting, P.J., de Laat, Bas, de Groot, Philip, Lenting, Peter, J., Muczynski, V., de Groot, P.G., Huskens, D., Wohner, Nikolett, Huskens, Dana, de Laat, B., Sebastian, Silvie, Muczynski, Vincent, Sebastian, S.   +13 more
core   +1 more source

Circulating levels of osteoprotegerin and sRANKL and the effect of methotrexate in patients with rheumatoid arthritis

Indian Journal of Rheumatology, 2018
Background: Receptor activator of nuclear factor κβ ligand (RANKL) and osteoprotegerin (OPG) are pivotal molecules involved in osteoclast activation and resorption.
Aadhaar Dhooria, Narendhiran Pandurangan, Karthik Vinay Mahesh, Suchet Sachdev, Aman Sharma, Shefali Sharma, Nidhi Gupta, Varun Dhir   +7 more
doaj   +1 more source