Results 71 to 80 of about 25,487 (238)

Osteoprotegerin and cardiovascular mortality in patients with non-ST elevation acute coronary syndromes [PDF]

, 2012
Objective: To assess the relationship between osteoprotegerin (OPG) and cardiovascular death, and the pathobiological mechanisms contributing to the association, in acute coronary syndromes (ACS). Design: Prospective observational.
Sabatine, Marc, Scirica, Benjamin M, Omland, Torbjørn, Murphy, Sabina A, Røysland, Ragnhild, Morrow, David A., Flyvbjerg, Allan, Bonaca, Marc P, Bjerre, Mette, Braunwald, Eugene   +9 more
core   +1 more source

Osteoprotegerin Expressed by Osteoclasts [PDF]

Journal of Dental Research, 2014
Osteoprotegerin (OPG) is secreted by stromal and osteoblastic lineage cells and inhibits osteoclastogenesis by preventing the interaction of receptor activator of nuclear factor-κB ligand (RANKL) with receptor activator of nuclear factor-κB (RANK).
J H, Kang, H M, Ko, J S, Moon, H I, Yoo, J Y, Jung, M S, Kim, J T, Koh, W J, Kim, S H, Kim   +8 more
openaire   +2 more sources

Disrupted joint clock is associated with rhythmic expression of bone destruction factors in collagen‐induced arthritis

Rheumatology &Autoimmunity, EarlyView.
Schematic Summary of Circadian Dysregulation in Arthritic Joints. This graphical abstract illustrates the key circadian disruptions observed in the collagen‑induced arthritis (CIA) model. The diagram depicts three main findings: (1) Nocturnal elevations in pro‑inflammatory cytokines (TNF‑α, IL‑6, IL‑17, IL‑1β, MIF) and bone‑destructive factors (DKK‑1 ...
Xiaogang Zhang, Mingming Zhang, Zhiqiang Wang, Jie Bai, Xing Feng, Yajing Wang, Zhenbin Li, Dongbao Zhao   +7 more
wiley   +1 more source

Age and Menopausal Status Affect Osteoprotegerin and Osteocalcin Levels in Women Differently, Irrespective of Thyroid Function [PDF]

, 2014
Osteoprotegerin (OPG) and osteocalcin (OC) are essential bone proteins. Recent studies have demonstrated that they are not secreted solely by bone cells; they play roles in the vascular function and energy metabolism, and they are influenced by multiple ...
Lilia N. Dakovska, Jordan D. Vlahov, Anna-Maria I. Borissova, Alexander D. Shinkov, Roussanka D. Kovatcheva, Iliana B. Atanassova, lliana B. Atanassova   +6 more
core   +1 more source

Alterations of bone proteins in medication‐related osteonecrosis of the jaw

European Journal of Oral Sciences, Volume 133, Issue 2, April 2025.
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert, Phillipp Brockmeyer, Philipp Kauffmann, Jan Wiegel, Florian Lautenbacher, Nicolai Miosge, Boris Schminke   +6 more
wiley   +1 more source

The relationship between BSP mRNA expression and 25(OH)D/OPG in peripheral blood of newly diagnosed T2DM patients with different bone mass

Endokrynologia Polska, 2020
INTRODUCTION: The objective of the study was to detect the levels of osteoprotegerin (OPG) and 25-hydroxyvitamin D [25(OH)D], as well as the expression of bone sialoprotein (BSP) mRNA, in the peripheral blood of patients with newly diagnosed type 2 ...
Sitong Fan, Zhe Wang, Qi Li, Liya Luo, Yuyu Zhu, Yan Yang   +5 more
doaj   +1 more source

Osteoprotegerin, vascular calcification and atherosclerosis [PDF]

Atherosclerosis, 2009
The association of bone pathologies with atherosclerosis has stimulated the search for common mediators linking the skeletal and the vascular system. Since its initial discovery as a key regulator in bone metabolism, osteoprotegerin (OPG) has become the subject of intense interest for its role in vascular disease and calcification. Studies in vitro and
Golledge, Jonathan, Van Campenhout, Ann
openaire   +3 more sources

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Osteoprotegerin and cardiovascular disease [PDF]

, 2010
The articles of this thesis are not available in Munin: 1. Vik A, Mathiesen EB, Noto AT, Sveinbjornsson B, Brox J and Hansen JB.: 'Serum osteoprotegerin is inversely associated with carotid plaque echogenicity in humans', Atherosclerosis (2007) 191(1 ...
Vik, Anders
core  

Osteoprotegerin ligand and osteoprotegerin: novel implications for osteoclast biology and bone metabolism [PDF]

European Journal of Endocrinology, 1999
The integrity of the skeleton depends upon bone remodeling, the permanent and controlled resorption of bone by osteoclasts (OC) and its subsequent replacement by bone-forming osteoblasts. An imbalance between bone resorption and bone formation results in osteoporosis (if bone resorption exceeds bone formation) or osteopetrosis (if bone formation ...
openaire   +2 more sources