Results 81 to 90 of about 20,163 (204)
Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence
Journal of Periodontal Research, EarlyView.This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang +3 more
wiley +1 more source
陆军军医大学学报Objective To investigate the expression of hepatoma-derived growth factor (HDGF) in hepatocellular carcinoma (HCC) and its effects on DNA damage, proliferation, migration, epithelial mesenchymal transition (EMT), and expression of osteoprotegerin (OPG ...
ZHANG Xi +3 more
doaj +1 more source
Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw
Oral Diseases, EarlyView.ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park +5 more
wiley +1 more source
Open Medicine, 2020 Osteoprotegerin (OPG) appears to be a very promising marker both in the diagnosis of abdominal aortic aneurysms (AAAs) and as a potential target in its treatment.
Migacz Maciej +3 more
doaj +1 more source
Role of osteoprotegerin (OPG) in cancer
Clinical Science, 2006 OPG (osteoprotegerin), a secreted member of the TNF (tumour necrosis factor) receptor superfamily, has a variety of biological functions which include the regulation of bone turnover. OPG is a potent inhibitor of osteoclastic bone resorption and has been investigated as a potential therapeutic for the treatment of both osteoporosis and tumour-induced ...
Holen, I, Shipman, C
openaire +2 more sources
The role of acquired host immunity in periodontal diseases
Periodontology 2000, EarlyView.Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane +2 more
wiley +1 more source
Inflammation and mechanical force‐induced bone remodeling
Periodontology 2000, EarlyView.Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
Periodontology 2000, EarlyView.Abstract The aim of this comprehensive review was to evaluate comparative studies on horizontal and fixed‐angle centrifugation methods for preparing platelet‐rich fibrin (PRF). Furthermore, additional studies utilizing horizontal PRF (H‐PRF) were systematically investigated.
Nima Farshidfar +6 more
wiley +1 more source
Intermediate type of Juvenile Paget's disease: A rare case in Indian population
Contemporary Clinical Dentistry, 2017 Juvenile Paget's disease (JPD), a rare genetic skeletal disorder characterized by accelerated bone turnover with elevated levels of serum alkaline phosphatase, presents in early childhood.
S Ravi Raja Kumar +3 more
doaj +1 more source
Periodontology 2000, EarlyView.Abstract The present narrative review aims to summarize the existing literature on recommendations for supportive periodontal care (SPC) in patients undergoing combined periodontal–orthodontic treatment. It outlines a comprehensive step‐4 treatment sequence in patients diagnosed with stage IV periodontitis and concurrent orthodontic problems.
Alexandra Stähli +6 more
wiley +1 more source