Results 81 to 90 of about 21,209 (213)
Oral Diseases, EarlyView.ABSTRACT Objective Oral squamous cell carcinoma (OSCC) frequently invades the mandibular bone, leading to metastasis and poor prognosis. This study aimed to evaluate the therapeutic effects of locally administered interleukin‐12 (IL‐12) using an immunocompetent mouse model mimicking the clinical features of mandibular bone invasion. Methods The effects
Shun Kasahara +11 more
wiley +1 more source
Oral Surgery, EarlyView.ABSTRACT Background Osteonecrosis of the jaws is associated with various drugs, including antiresorptives such as bisphosphonates and denosumab, as well as antiangiogenics. These drugs are used for the treatment of multiple diseases, notably osteoporosis, bone metastases, Paget's disease, osteogenesis imperfecta, malignant hypocalcaemia, among others ...
Rodríguez Naranjo Julia Alexandra +3 more
wiley +1 more source
Intermediate type of Juvenile Paget's disease: A rare case in Indian population
Contemporary Clinical Dentistry, 2017 Juvenile Paget's disease (JPD), a rare genetic skeletal disorder characterized by accelerated bone turnover with elevated levels of serum alkaline phosphatase, presents in early childhood.
S Ravi Raja Kumar +3 more
doaj +1 more source
The role of acquired host immunity in periodontal diseases
Periodontology 2000, EarlyView.Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane +2 more
wiley +1 more source
Role of osteoprotegerin (OPG) in cancer
Clinical Science, 2006 OPG (osteoprotegerin), a secreted member of the TNF (tumour necrosis factor) receptor superfamily, has a variety of biological functions which include the regulation of bone turnover. OPG is a potent inhibitor of osteoclastic bone resorption and has been investigated as a potential therapeutic for the treatment of both osteoporosis and tumour-induced ...
Holen, I, Shipman, C
openaire +2 more sources
Inflammation and mechanical force‐induced bone remodeling
Periodontology 2000, EarlyView.Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
Annals of Agricultural and Environmental Medicine, 2015 Objective The aim of the study was to assess differences in circulating osteocalcin (OC) and osteoprotegerin (OPG), as well as in their expression in subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT) and placental tissue obtained from ...
Beata Telejko +11 more
doaj +1 more source
Periodontology 2000, EarlyView.Abstract The present narrative review aims to summarize the existing literature on recommendations for supportive periodontal care (SPC) in patients undergoing combined periodontal–orthodontic treatment. It outlines a comprehensive step‐4 treatment sequence in patients diagnosed with stage IV periodontitis and concurrent orthodontic problems.
Alexandra Stähli +6 more
wiley +1 more source
Osteoporosis in Systemic Autoinflammatory Diseases: A Case-Control Study
Frontiers in Endocrinology, 2019 Objective: To assess if patients affected by systemic autoinflammatory diseases (SAIDs) present an increased risk of osteoporosis (OP).Methods: Forty adults patients referred to the Rheumatology Unit of Padova University Hospital affected by Familial ...
Sara Bindoli +5 more
doaj +1 more source
Periodontology 2000, EarlyView.Abstract Background Understanding periodontal diseases through a biological lens has been a central aim in periodontal research. Visionary pioneers in the field established the foundations of our knowledge, providing invaluable insights into disease mechanisms and progression.
Nagihan Bostanci +2 more
wiley +1 more source