Results 91 to 100 of about 21,209 (213)

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Osteoprotegerin mediates adipogenesis in obesity

Journal of Advanced Research
Adipogenesis, the process of white adipose tissue expansion, plays a critical role in the development of obesity. Osteoprotegerin (OPG), known for its role in bone metabolism regulation, emerges as a potential regulator in mediating adipogenesis during obesity onset.This study aims to elucidate the involvement of OPG in adipogenesis during the early ...
Zipan Lyu, Yau-Tuen Chan, Yuanjun Lu, Tsz Fung Lam, Xingyao Wu, Junyu Wu, Lin Xu, Wei Yang, Cheng Zhang, Linda Lidan Zhong, Ning Wang   +10 more
openaire   +4 more sources

Long‐term stability of horizontal bone augmentation at implant sites

Periodontology 2000, EarlyView.
Abstract Horizontal bone augmentation is a fundamental surgical procedure in regenerative implant dentistry. In recent decades, this procedure has evolved, enabling clinicians to achieve predictable and stable horizontal bone augmentation that supports dental implant restorations.
Jia‐Hui Fu, Hui Jia Sophia Choo, Ding‐Sen Ong, Henry Kwek   +3 more
wiley   +1 more source

Association of Bone Turnover Biomarkers and Subclinical Atherosclerosis in Subjects with Type 2 Diabetes: A Case-Control Study

Clinical Diabetology
OBJECTIVE: The current study aims to assess the relationship between serum osteocalcin (OCN) and osteoprotegerin (OPG) levels and subclinical atherosclerosis.
Nagwa A. Lachine, Eman Y. Morsy, Abdelaziz Elnekiedy, Mohamed A. Sadaka, Gehan I. Khalil, Hesham G. Imam, Heba S. Kassab, Noha G. Amin   +7 more
doaj   +1 more source

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

Periodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker, Sandra H. Stuhr, Gustavo Avila‐Ortiz, Andrea Pilloni, Lorenzo Marini, Rogerio Castilho, Beth I. Wallace, Yvonne L. Hernandez‐Kapila   +7 more
wiley   +1 more source

Emerging risk factors influencing the occurrence of peri‐implantitis

Periodontology 2000, EarlyView.
Abstract Background The objective of the present review is to explore the evidence and biological plausibility of factors that may expose dental implants to a greater likelihood of developing peri‐implantitis. Material and Methods An electronic screening on the PubMed library the was carried out to identify potential emerging factors that influence the
Alberto Monje, Ronald E. Jung, Cristina Valles, Nadja Naenni   +3 more
wiley   +1 more source

Bone biology in aging periodontal and peri‐implant tissues

Periodontology 2000, EarlyView.
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa, Giuseppe Intini, Daniel Clark   +2 more
wiley   +1 more source

Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance

Periodontology 2000, EarlyView.
Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf, Ulrike Schulze‐Späte, Thomas Van Dyke, Stefan Wolfart, Thomas Dietrich, Alberto Ortiz, Zhuojun Wu, Joachim Jankowski   +7 more
wiley   +1 more source

Histological Evaluation of Radiotherapy-Induced Changes in Periodontal Tissues in a Rat Model of Experimental Periodontitis

Biology
Background/Objectives: Radiotherapy is a cornerstone of head and neck cancer treatment, but it can adversely affect periodontal tissues by impairing vascularity, cellularity, and healing capacity.
Batuhan Hazar Ayşeşek, Buse Başak Feyizoğlu, Vakur Olgaç, İlknur Bingül, Nazlı Ayşeşek, Ülkü Başer, Ayşen Gülden Işık   +6 more
doaj   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source