Results 111 to 120 of about 20,163 (204)

The Rising Burden of Osteosarcopenia in Older Adults: A Narrative Review of Pathophysiology, Diagnostic Challenges, and Therapeutic Perspectives

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Osteosarcopenia, defined as the coexistence of osteoporosis and sarcopenia, is an emerging geriatric syndrome linked to the musculoskeletal decline associated with aging. It is correlated with an increased risk of falls, fractures, disability, and mortality.
Javeria Taj, Rabia Zafar, Joshua Ekouo, Ayesha Junaid, Dujardin Makeda, Kinza Latif, Hermann Yokolo   +6 more
wiley   +1 more source

Reciprocal Macrophage‐MSC Crosstalk Drives Immunomodulatory and Regenerative Phenotypes in a Mineralized Collagen Scaffold

Journal of Biomedical Materials Research Part A, Volume 114, Issue 6, June 2026.
Macrophage‐MSC interactions are dynamic. Following injury, neutral (M0) macrophages arrive at the defect site and polarize towards M1 (pro‐inflammatory) macrophages, which can secrete inflammatory and cell recruitment factors. MSCs in this inflammatory defect can take on a licensed state in which they secrete a series of immunomodulatory factors that ...
Vasiliki Kolliopoulos, Maxwell Polanek, Hashni E. Vidana Gamage, Melisande Wong Yan Ling, Aleczandria Tiffany, Erik R. Nelson, Kara L. Spiller, Brendan A. C. Harley   +7 more
wiley   +1 more source

The levels of osteoprotegerin, transforming growth factor-β, and some cytokines in women with coronary heart disease concurrent with severe osteoporosis

Терапевтический архив, 2015
Aim. To determine the serum level of cytokines in women with coronary heart disease (CHD) concurrent with osteoporosis (OP) and in those with isolated CHD; to assess a relationship of the levels of cytokines, osteoprotegerin (OPG), and transforming ...
S Yu Tsarenok, V V Gorbunov
doaj  

Controversies Surrounding Critical‐Size Defects: Influence of Age and Biological Characteristics

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 6, June 2026.
ABSTRACT Critical‐size defects (CSDs) in craniofacial reconstruction refer to osseous gaps that fail to heal spontaneously, increasing the risk of neurological impairment and craniofacial dysmorphology. Despite decades of investigation, controversy still exists surrounding the definition of CSDs, with criteria varying across species, experimental ...
Andrew Nordlund, Hana Shah, Nicholas A. Mirsky, Kashyap K. Tadisina, Arturo J. Rios‐Diaz, Vasudev Vivekanand Nayak, Estevam A. Bonfante, Paulo G. Coelho   +7 more
wiley   +1 more source

Biochemical bone biomarkers in plasma cell dyscrasias

British Journal of Haematology, Volume 208, Issue 6, Page 1909-1923, June 2026.
Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador, Rohit Vijjhalwar, Muhammad Kassim Javaid, Claire M. Edwards, Karthik Ramasamy   +4 more
wiley   +1 more source

Osteoblast‐Derived Osteomodulin Suppresses Bone Loss in Osteoporosis by Inhibiting Osteoclastogenesis

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Osteoblast‐derived matricellular protein osteomodulin (OMD) critically regulates bone remodeling homeostasis via directly and competitively binding to RANKL, the master cytokine driving osteoclast formation. OMD shares overlapping binding sites on RANKL with osteoprotegerin and functional receptor RANK.
Meiling Jing, Xiaohan Zhu, Yueyi Yang, Xuchen Hu, Wenduo Tan, Xiaoyu Liu, Yujie Zhang, Xin Wang, Chenguang Niu, Zhengwei Huang   +9 more
wiley   +1 more source

Osteoprotegerin and fibroblast growth factor 23 in the development of cardiovascular events in chronic kidney disease

Терапевтический архив, 2014
AIM: To study the role of the bone mineral metabolic mediators osteoprotegerin (OPG) and fibroblast growth factor 23 (FGF-23) in the mechanisms of cardiovascular events (CVEs) in chronic kidney disease (CKD)/MATERIAL AND METHODS: Sixty-eight patients (30
F U Dzgoeva, T M Gatagonova, T L Bestaeva, M Iu Sopoev, B G Bazaeva, O V Khamitsaeva   +5 more
doaj  

Correction: Bednarek et al. Serum Osteoprotegerin Level Is Not a Localizing Biomarker of Atherosclerosis Affected by Kidney Function. <i>Diagnostics</i> 2026, <i>16</i>, 786. [PDF]

Diagnostics (Basel)
Bednarek AM, Owczarek AJ, Dziadosz D, Olszanecka-Glinianowicz M, Chudek JT.   +4 more
europepmc   +1 more source

Osteoprotegerin [PDF]

, 2017
openaire   +2 more sources

Circulating Wnt Signaling Inhibitors and Osteoprotegerin in Women with Newly Diagnosed Overt Thyroid Dysfunction. [PDF]

Metabolites
Miteva MZ, Orbetzova MM, Nonchev BI, Davcheva DM, Gigov K.   +4 more
europepmc   +1 more source