Results 121 to 130 of about 27,421 (247)

Beyond biologic sex: Exploratory insights into the heterogeneity of hormonal and contextual drivers of periodontal and peri‐implant outcomes

Periodontology 2000, EarlyView.
Abstract Background Periodontal and peri‐implant diseases are multifactorial inflammatory conditions influenced by microbial, host, hormonal, genetic, and behavioral factors. Although sex‐based differences in immune and inflammatory responses are well recognized in medicine, the extent to which biologic sex and hormonal status influence the prevalence,
Caitlin Neapole, Mark Gettas, Roberto Farina, Yvonne Hernandez‐Kapila   +3 more
wiley   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Evaluation of Serum Fetuin-A and Osteoprotegerin Levels in Patients with Psoriasis

, 2016
Psoriasis patients are determined to have a high ratio of coronary artery calcification. Fetuin-A and osteoprotegerin are systemic calcification inhibitors and related to vascular calcification and cardiovascular mortality.
Murat Can, Berrak Guven, Cagatay Buyukuysal, Saniye Çinar, Ayca Gorkem Mungan, Mehmet Genc, Serefden Acikgoz, Bilgehan Açıkgöz   +7 more
core   +1 more source

Association of Bone Turnover Biomarkers and Subclinical Atherosclerosis in Subjects with Type 2 Diabetes: A Case-Control Study

Clinical Diabetology
OBJECTIVE: The current study aims to assess the relationship between serum osteocalcin (OCN) and osteoprotegerin (OPG) levels and subclinical atherosclerosis.
Nagwa A. Lachine, Eman Y. Morsy, Abdelaziz Elnekiedy, Mohamed A. Sadaka, Gehan I. Khalil, Hesham G. Imam, Heba S. Kassab, Noha G. Amin   +7 more
doaj   +1 more source

Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

Osteoprotegerin and cardiovascular mortality in patients with non-ST elevation acute coronary syndromes

, 2012
Objective: To assess the relationship between osteoprotegerin (OPG) and cardiovascular death, and the pathobiological mechanisms contributing to the association, in acute coronary syndromes (ACS). Design: Prospective observational.
Sabatine, Marc, Scirica, Benjamin M, Omland, Torbjørn, Murphy, Sabina A, Røysland, Ragnhild, Morrow, David A., Flyvbjerg, Allan, Bonaca, Marc P, Bjerre, Mette, Braunwald, Eugene   +9 more
core   +1 more source

Peri‐implantitis and systemic inflammation: Current evidence, biological plausibility, and research gaps

Periodontology 2000, EarlyView.
Abstract Background Peri‐implantitis is a biofilm‐associated inflammatory condition characterized by peri‐implant mucosal inflammation and progressive bone loss. The prevalence of peri‐implantitis continues to rise among patients with dental implants. Although peri‐implantitis and periodontitis share similar inflammatory phenotypes, histopathological ...
Yumeng Yan, Jeanie Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source

Histological Evaluation of Radiotherapy-Induced Changes in Periodontal Tissues in a Rat Model of Experimental Periodontitis

Biology
Background/Objectives: Radiotherapy is a cornerstone of head and neck cancer treatment, but it can adversely affect periodontal tissues by impairing vascularity, cellularity, and healing capacity.
Batuhan Hazar Ayşeşek, Buse Başak Feyizoğlu, Vakur Olgaç, İlknur Bingül, Nazlı Ayşeşek, Ülkü Başer, Ayşen Gülden Işık   +6 more
doaj   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source