Results 1 to 10 of about 54,052 (278)
Immunohistochemical evaluation of osteopontin expression in triple-negative breast cancer
Archives of Medical Science, 2020 Introduction Triple-negative breast cancer (TNBC) is associated with lack of expression of estrogen and progesterone receptors and HER2 and is the subgroup of breast cancers with the worst prognosis.
Magdalena Niedolistek +11 more
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Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers
Egyptian Journal of Chest Disease and Tuberculosis, 2015 Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified.
Ahmed A Ali +4 more
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Disease Models & Mechanisms, 2013 SUMMARY Osteopontin is secreted by skeletal muscle myoblasts and stimulates their proliferation. Expression of osteopontin in skeletal muscle is upregulated in pathological conditions including Duchenne muscular dystrophy, and recent evidence suggests ...
Kitipong Uaesoontrachoon +3 more
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Scientific Reports, 2022 Ischemic stroke is a serious neurological disorder that is associated with dysregulation of the neurovascular unit (NVU) and impairment of the blood–brain barrier (BBB).
Daniel Spitzer +11 more
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Journal of Hematology & Oncology, 2011 The matrix protein osteopontin has been shown to be a marker of osteoclastic activity in multiple myeloma patients, as well as a regulator of angiogenesis.
Kotsis Vasileios +7 more
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Aerosol delivery of small hairpin osteopontin blocks pulmonary metastasis of breast cancer in mice. [PDF]
PLoS ONE, 2010 Metastasis to the lung may be the final step in the breast cancer-related morbidity. Conventional therapies such as chemotherapy and surgery are somewhat successful, however, metastasis-related breast cancer morbidity remains high. Thus, a novel approach
Kyeong-Nam Yu +17 more
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Osteopontin as a Link between Inflammation and Cancer: The Thorax in the Spotlight
Cells, 2019 The glycoprotein osteopontin (OPN) possesses multiple functions in health and disease. To this end, osteopontin has beneficial roles in wound healing, bone homeostasis, and extracellular matrix (ECM) function.
Anne-Sophie Lamort +3 more
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Expression and function of osteopontin in vascular adventitial fibroblasts and pathological vascular remodeling. [PDF]
PLoS ONE, 2011 Osteopontin is known to play important roles in various diseases including vascular disorders. However, little is known about its expression and function in vascular adventitial fibroblasts.
Xin Jin +4 more
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Osteopontin in patients with chronic obstructive pulmonary disease and coronary heart disease
Alʹmanah Kliničeskoj Mediciny, 2023 Background: Osteopontin is a protein expressed by various cell types, such as endothelial and epithelial cells, osteoclasts, hepatocytes, smooth muscle cells, activated macrophages, and T-cells.
Natalia A. Suvorova +2 more
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Tumor Biology, 2017 Osteopontin-c splicing isoform activates ovarian cancer progression features. Imbalanced expression of splicing factors from serine/arginine -rich and heterogeneous ribonucleoproteins families has been correlated with the generation of oncogenic splicing
Durval Santos Marques +4 more
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