Results 21 to 30 of about 52,783 (282)
Scientific Reports, 2022 Ischemic stroke is a serious neurological disorder that is associated with dysregulation of the neurovascular unit (NVU) and impairment of the blood–brain barrier (BBB).
Daniel Spitzer +11 more
doaj +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
Intraluminal application of vascular endothelial growth factor enhances healing of microvascular anastomosis in a rat model [PDF]
, 2005 Background: Early reconstitution after injury to the endothelium is an important feature for reducing a number of vessel wall pathologies. We investigated the effect of vascular endothelial growth factor ( VEGF) and its impact on the vascular remodeling ...
Hollenberg, S. M. +8 more
core +2 more sources
Journal of Hematology & Oncology, 2011 The matrix protein osteopontin has been shown to be a marker of osteoclastic activity in multiple myeloma patients, as well as a regulator of angiogenesis.
Kotsis Vasileios +7 more
doaj +1 more source
Development of an electrochemical RNA-aptasensor to detect human osteopontin [PDF]
, 2015 Electrochemical aptasensors may be used to detect protein biomarkers related to tumor activity. Osteopontin (OPN), a protein present in several body fluids, has been suggested as a potential biomarker since its overexpression seems to be associated with ...
Dias, Luís G. +9 more
core +1 more source
Aerosol delivery of small hairpin osteopontin blocks pulmonary metastasis of breast cancer in mice. [PDF]
PLoS ONE, 2010 Metastasis to the lung may be the final step in the breast cancer-related morbidity. Conventional therapies such as chemotherapy and surgery are somewhat successful, however, metastasis-related breast cancer morbidity remains high. Thus, a novel approach
Kyeong-Nam Yu +17 more
doaj +1 more source
Osteopontin as a Link between Inflammation and Cancer: The Thorax in the Spotlight
Cells, 2019 The glycoprotein osteopontin (OPN) possesses multiple functions in health and disease. To this end, osteopontin has beneficial roles in wound healing, bone homeostasis, and extracellular matrix (ECM) function.
Anne-Sophie Lamort +3 more
doaj +1 more source
Expression and function of osteopontin in vascular adventitial fibroblasts and pathological vascular remodeling. [PDF]
PLoS ONE, 2011 Osteopontin is known to play important roles in various diseases including vascular disorders. However, little is known about its expression and function in vascular adventitial fibroblasts.
Xin Jin +4 more
doaj +1 more source
Osteopontin in patients with chronic obstructive pulmonary disease and coronary heart disease
Alʹmanah Kliničeskoj Mediciny, 2023 Background: Osteopontin is a protein expressed by various cell types, such as endothelial and epithelial cells, osteoclasts, hepatocytes, smooth muscle cells, activated macrophages, and T-cells.
Natalia A. Suvorova +2 more
doaj +1 more source
Biomedicines, 2021 Osteopontin is a member of the proinflammatory cytokine network, a complex system that involves many chemokines, cytokines, and growth factors. The aim of the present study was to study the associations between osteopontin and a large number of ...
Anders Larsson +4 more
doaj +1 more source