Results 41 to 50 of about 52,783 (282)
Journal of Pharmacological Sciences, 2005 Osteopontin has been reported to have an important role in cardiac fibrosis. However, little is known about the effects of angiotensin-converting enzyme inhibitor (ACEI) and angiotensin type 1 receptor blockers (ARB) on osteopontin expression in ...
Takanori Kusuyama +10 more
doaj +1 more source
, 2018 Previous studies have shown that osteopontin (OPN) can enhance infant resistance to infection. However, the underlying mechanisms remain to be explored.
Xiaoyan Chen (146508) +5 more
core +1 more source
Osteopontin Activation and Microcalcification in Venous Grafts Can Be Modulated by Dexamethasone
Cells, 2023 Background: Osteopontin has been implicated in vascular calcification formation and vein graft intimal hyperplasia, and its expression can be triggered by pro-inflammatory activation of cells.
Liam W. McQueen +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source
Monoclonal Antibodies Against Osteopontin [PDF]
, 2008 The present invention relates to reagents and methods for the detection of osteopontin fragments and distinguishing them from each other and from the full-length osteopontin protein.
Liaw, Lucy +2 more
core +1 more source
Egyptian Journal of Chest Disease and Tuberculosis, 2013 Purpose: In malignant pleural mesothelioma (MPM), early assessment of disease status is important. We evaluated the role of mesothelin and osteopontin biomarkers in distinguishing MPM from benign pleural disease. We also, evaluated whether mesothelin and
Fawzy M. Amany +6 more
doaj +1 more source
EMBO Molecular Medicine, 2021 Graphical Abstract This study independently confirms increased levels of osteopontin in COVID‐19 patients but also suggests that osteopontin cannot be used as a biomarker of SARS‐CoV‐2 infection, as elevated levels of circulating osteopontin are found in
Giuseppe Cappellano +6 more
doaj +1 more source
Expression and function of osteopontin variants in HCV-related liver disease and hepatocellular carcinoma. [PDF]
, 2010 Osteopontin (OPN) is a highly secreted multi-functional sialoprotein that is widely expressed in tissues, blood and urine. It is involved in a number of normal physiological functions, but is also significantly elevated in a number of cancers.
Phillips, Renee Jade
core
Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress
Advanced Science, EarlyView.Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen +11 more
wiley +1 more source
The Yin-Yang of osteopontin in nervous system diseases: damage versus repair
Neural Regeneration Research, 2021 Osteopontin is a broadly expressed pleiotropic protein, and is attracting increased attention because of its role in the pathophysiology of several inflammatory, degenerative, autoimmune, and oncologic diseases.
Giuseppe Cappellano +9 more
doaj +1 more source