Results 1 to 10 of about 308,702 (119)

Mesenchymal Stem/Stromal Cells Derived from Cervical Cancer Promote M2 Macrophage Polarization

Cells, 2023
Macrophages with the M2 phenotype promote tumor development through the immunosuppression of antitumor immunity. We previously demonstrated the presence of mesenchymal stem/stromal cells (MSCs) in cervical cancer (CeCa-MSCs), suggesting an immune ...
Víctor Adrián Cortés-Morales, Luis Chávez-Sánchez, Leticia Rocha-Zavaleta, Sandra Espíndola-Garibay, Alberto Monroy-García, Marta Elena Castro-Manrreza, Guadalupe Rosario Fajardo-Orduña, Teresa Apresa-García, Marcos Gutiérrez-de la Barrera, Héctor Mayani, Juan José Montesinos   +10 more
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In Vitro Evidence of Differential Immunoregulatory Response between MDA-MB-231 and BT-474 Breast Cancer Cells Induced by Bone Marrow-Derived Mesenchymal Stromal Cells Conditioned Medium

Current Issues in Molecular Biology, 2022
Inside tumors, cancer cells display several mechanisms to create an immunosuppressive environment. On the other hand, by migration processes, mesenchymal stromal cells (MSCs) can be recruited by different cancer tumor types from tissues as distant as ...
Víctor M. Arenas-Luna, Juan J. Montesinos, Víctor A. Cortés-Morales, José R. Navarro-Betancourt, Janneth Peralta-Ildefonso, Bulmaro Cisneros, Salomón Hernández-Gutiérrez   +6 more
doaj   +1 more source

High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

European Journal of Histochemistry, 2022
Desmoplastic stroma (DS) and the epithelial-to-mesenchymal transition (EMT) play a key role in pancreatic ductal adenocarcinoma (PDAC) progression. To date, however, the combined expression of DS and EMT markers, and their association with variations in
Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos   +15 more
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The Beneficial Effects of Herbal Therapy (Zayesh Booalidaroo + Safoof-e Hefz + Royal Jelly) on Male Infertility [PDF]

Research in Molecular Medicine, 2023
Background: Several studies have recently been conducted on herbal plants due to their growing medicinal usage. Since it is estimated that male partner causes 40% of infertility, we aimed to examine the effects of herbal combinations, including Zayesh ...
Leila Naserpour, Hoda Fazaeli, Seyed Abbas Seyed Ebrahimi, Seyedeh Saeideh Sahraei, Naser Kalhor, Mohamad Heydari, Zahra Ebrahimi   +6 more
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Human Bone Marrow Mesenchymal Stem/Stromal Cells Exposed to an Inflammatory Environment Increase the Expression of ICAM-1 and Release Microvesicles Enriched in This Adhesive Molecule: Analysis of the Participation of TNF-α and IFN-γ

Journal of Immunology Research, 2020
Bone marrow mesenchymal stem/stromal cells (BM-MSCs) have immunoregulatory capacity; therefore, they have been used in different clinical protocols in which it is necessary to decrease the immune response.
Juan J. Montesinos, Lucero López-García, Víctor A. Cortés-Morales, Lourdes Arriaga-Pizano, Ricardo Valle-Ríos, Guadalupe R. Fajardo-Orduña, Marta E. Castro-Manrreza   +6 more
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Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

PLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova, Ira S Cohen, Sergey V Doronin   +2 more
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The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells [PDF]

Advanced Pharmaceutical Bulletin, 2015
Bone marrow microenvironment contains cellular and acellular compartments. The cellular compartment includes hematopoietic stem cells, mesenchymal stem cells and some other stromal cell types, while the acellular compartment is composed of scaffold ...
Mahshid Saleh, karim Shamsasanjan, Aliakbar Movassaghpourakbari, Parvin Akbarzadehlaleh, Zahra Molaeipour   +4 more
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Odontogenic MSC Heterogeneity: Challenges and Opportunities for Regenerative Medicine

Frontiers in Physiology, 2022
Cellular heterogeneity refers to the genetic and phenotypic differences among cells, which reflect their various fate choices, including viability, proliferation, self-renewal probability, and differentiation into different lineages.
Yuan Chen, Zhaoyichun Zhang, Xiaoxue Yang, Anqi Liu, Shiyu Liu, Jianying Feng, Kun Xuan   +6 more
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Identification of Diagnostic Biomarkers by Bioinformatics Analysis in the Inflamed and Non-inflamed Intestinal Mucosa of Patients With Crohn’s Disease

Research in Molecular Medicine, 2021
Background: Crohn’s Disease (CD) is a type of inflammatory bowel disease that, despite its unknown etiology, is generally associated with genetics, immune system, and environmental factors. In this study, we uncover transcriptional signatures in patients
Mohsen Sheykhhasan, Hoda Fazaeli, Azar Sheikholeslami, Seyed Abbas Seyedebrahimi, Seyed Jalal Eshagh Hoseini, Naser Kalhor   +5 more
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Immunoregulation by Mesenchymal Stem Cells: Biological Aspects and Clinical Applications

Journal of Immunology Research, 2015
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into mesenchymal lineages and that can be isolated from various tissues and easily cultivated in vitro.
Marta E. Castro-Manrreza, Juan J. Montesinos   +1 more
doaj   +1 more source