Results 31 to 40 of about 361,860 (315)

Dissecting the impact of Frizzled receptors in Wnt/beta-catenin signaling of human mesenchymal stem cells [PDF]

, 2012
Wnt/beta-catenin signaling is of fundamental importance in the regulation of self-renewal, migration/invasion, and differentiation of human mesenchymal stem cells (hMSCs).
Ruiz-Heinrich, Lourdes, Peröbner, Iris, Capovilla, Simon, Neth, Peter, Fernsebner, Katharina, Lechner, F., Jochum, M., Neth, P., Kolben, Thomas, Geissler, Claudia, Fernsebner, K., Geissler, C., Perobner, I., Peroebner, Iris, Jochum, Marianne, Lechner, Felix, Ruiz-Heinrich, L., Kolben, T., Capovilla, S.   +18 more
core   +1 more source

Characterization of early mouse mesenchymal stem/progenitor cells for generating cartilage and study their role in endochondral ossification [PDF]

, 2016
Mesenchymal stem/ stromal cells (MSCs) isolated from mice have allowed to address some of the major issues that could not be investigated by using human MSCs.
Jaiswal, Sumit
core   +1 more source

Transfer of mitochondria from mesenchymal stem cells derived from induced pluripotent stem cells attenuates hypoxia-ischemia-induced mitochondrial dysfunction in PC12 cells

Neural Regeneration Research, 2020
Mitochondrial dysfunction in neurons has been implicated in hypoxia-ischemia-induced brain injury. Although mesenchymal stem cell therapy has emerged as a novel treatment for this pathology, the mechanisms are not fully understood. To address this issue,
Yan Yang, Gen Ye, Yue-Lin Zhang, Hai-Wei He, Bao-Qi Yu, Yi-Mei Hong, Wei You, Xin Li   +7 more
doaj   +1 more source

Immunobiology of mesenchymal stem cells [PDF]

Cell Death & Differentiation, 2013
Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively expanded in vitro. Although their true in situ properties and biological functions remain to be elucidated, these in vitro expanded cells have been shown to possess potential to differentiate into specific cell lineages.
Ma, S, Xie, N, Li, W, Yuan, B, Shi, Y, Wang, Y   +5 more
openaire   +2 more sources

Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts

, 2010
Introduction: Amniotic fluid harbors cells indicative of all three germ layers, and pluripotent fetal amniotic fluid stem cells (AFSs) are considered potentially valuable for applications in cellular therapy and tissue engineering.
Bernd Groner, Vafaizadeh, Vida, Groner, Bernd, Petra AB Klemmt, Vida Vafaizadeh, Klemmt, Petra A. B.   +5 more
core   +1 more source

Mesenchymal Stem Cells Promote Oligodendroglial Differentiation in Hippocampal Slice Cultures [PDF]

, 2009
We have previously shown that soluble factors derived from mesenchymal stem cells (MSCs) induce oligodendrogenic fate and differentiation in adult rat neural progenitors (NPCs) in vitro.
Aigner, L., Götz, Magdalena, Blümcke, I., Berninger, Benedikt, Siebzehnrubl, Florian, Couillard-Despres, Sebastien, Bogdahn, Ulrich, Caioni, Massimiliano, Kandasamy, M., Pöhler, A.M., Couillard-Despres, S., Berninger, B., Weidner, N., Aigner, Ludwig, Götz, M., Siebzehnrubl, F.A., Bogdahn, U., Weidner, Norbert, Sandner, B., Poehler, Anne-Maria, Sandner, Beatrice, Goetz, Magdalena, Rivera, Francisco J., Caioni, M., Bluemcke, Ingmar, Siebzehnrubl, Florian A., Kandasamy, Mahesh, Rivera, F.J.   +27 more
core   +1 more source

A Comparative Study on the Effects of Mesenchymal Stem Cells and Their Conditioned Medium on Caco-2 Cells as an In Vitro Model for Inflammatory Bowel Disease

International Journal of Cell Biology
Recent research indicates that mesenchymal stem cells (MSCs), known for their anti-inflammatory and anti-infectious properties, could be a promising alternative for treating inflammatory diseases such as inflammatory bowel disease (IBD).
Naser Kalhor, Hoda Fazaeli, Faezeh Davoodi Asl, Azar Sheikholeslami, Seyed Jalal Eshagh Hoseini, Mohsen Sheykhhasan   +5 more
doaj   +1 more source

Gender difference in the neuroprotective effect of rat bone marrow mesenchymal cells against hypoxia-induced apoptosis of retinal ganglion cells

Neural Regeneration Research, 2016
Bone marrow mesenchymal stem cells can reduce retinal ganglion cell death and effectively prevent vision loss. Previously, we found that during differentiation, female rhesus monkey bone marrow mesenchymal stem cells acquire a higher neurogenic potential
Jing Yuan, Jian-xiong Yu
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

GATA2 regulates differentiation of bone marrow-derived mesenchymal stem cells

Haematologica, 2014
The bone marrow microenvironment comprises multiple cell niches derived from bone marrow mesenchymal stem cells. However, the molecular mechanism of bone marrow mesenchymal stem cell differentiation is poorly understood. The transcription factor GATA2 is
Mayumi Kamata, Yoko Okitsu, Tohru Fujiwara, Masahiko Kanehira, Shinji Nakajima, Taro Takahashi, Ai Inoue, Noriko Fukuhara, Yasushi Onishi, Kenichi Ishizawa, Ritsuko Shimizu, Masayuki Yamamoto, Hideo Harigae   +12 more
doaj   +1 more source