Results 31 to 40 of about 295,945 (266)

Testosterone Propionate Promotes Proliferation and Viability of Bone Marrow Mesenchymal Stem Cells while Preserving Their Characteristics and Inducing Their Anti-Cancer Efficacy

Balkan Medical Journal, 2023
Background: Various studies have reported the effects of testosterone on different cell types, yet bone marrow-derived mesenchymal stem cells’ cellular responses to testosterone remain unknown. Aims: To investigate the effects of testosterone propionate,
Başak Aru, Tuba Akdeniz, Hüsniye Dağdeviren, Gizem Gürel, Gülderen Yanıkkaya Demirel   +4 more
doaj   +1 more source

Mesenchymal stem cells

Annals of Medicine, 2005
About 40 years ago Friedenstein described stromal cells in the bone marrow that were spindle shaped and proliferate to form colonies. These cells attach to plastic and are able to differentiate under defined in vitro conditions into multiple cell types present in many different tissues, e.g. osteoblasts, chondroblasts, adipocytes, etc.
openaire   +2 more sources

Mesenchymal stem cells and their microenvironment

Frontiers in Bioscience, 2011
Mesenchymal stem cells (MSC) are multipotent stem cells that hold promise for an expanding list of therapeutic uses, not only due to their ability to differentiate into all connective tissues including bone, fat and cartilage, but additionally due to their trophic and anti-inflammatory effects which contribute to healing and tissue regeneration ...
Ingrid U, Schraufstatter, Richard G, Discipio, Sophia, Khaldoyanidi   +2 more
openaire   +2 more sources

Mesenchymal Stem Cells in Cardiology [PDF]

, 2016
Cardiovascular disease (CVD) accounts for more deaths globally than any other single disease. There are on average 1.5 million episodes of myocardial infarction (heart attack) each year in the United States alone with roughly one-third resulting in death.
Ian A, White, Cristina, Sanina, Wayne, Balkan, Joshua M, Hare   +3 more
openaire   +2 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

In vitro exploration of the therapeutic potential of mesenchymal stem cell conditioned medium in endometriosis treatment by targeting apoptosis and cellular migration

International Journal of Reproductive BioMedicine
Background: Endometriosis, a common gynecological disorder involving ectopic endometrial tissue, leads to infertility and chronic pain. Dysregulated apoptosis and abnormal cell migration are key pathological features. Given current treatment limitations,
Hassan Hedayatnia, Naser Kalhor
doaj   +1 more source

Mesenchymal Stem Cells Immunosuppressed IL-22 in Patients with Immune Thrombocytopenia via Soluble Cellular Factors

Journal of Immunology Research, 2015
Mesenchymal stem cells are immunoregulation cells. IL-22 plays an important role in the pathogenesis of immune thrombocytopenia. However, the effects of mesenchymal stem cells on IL-22 production in patients with immune thrombocytopenia remain unclear ...
Mei Wu, Hongfeng Ge, Shue Li, Hailiang Chu, Shili Yang, Xiaoxing Sun, Zhenxia Zhou, Xiongpeng Zhu   +7 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Advances in stem cell therapy for erectile dysfunction: preclinical evidence and emerging therapeutic approaches

Frontiers in Medicine
The inability to get or sustain an erection strong enough for fulfilling sexual performance is the hallmark of the common disorder known as erectile dysfunction (ED). It mostly affects a significant percentage of men worldwide, particularly those aged 40
Xiaoliang Fu, Azar Sheikholeslami, Ulanbek Zhanbyrbekuly, Faezeh Davoodi Asl, Nadiar M. Mussin, Hoda Fazaeli, Karim Daniyalov, Nader Tanideh, Nader Tanideh, Nader Tanideh, Mahdi Mahdipour, Mahdi Mahdipour, Madina A. Kurmanalina, Amin Tamadon, Amin Tamadon, Amin Tamadon   +15 more
doaj   +1 more source

Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1

Haematologica, 2009
Background Conventionally, mesenchymal stem cells are functionally isolated from primary tissue based on their capacity to adhere to a plastic surface. This isolation procedure is hampered by the unpredictable influence of co-cultured hematopoietic and ...
Venkata Lokesh Battula, Sabrina Treml, Petra M. Bareiss, Friederike Gieseke, Helene Roelofs, Peter de Zwart, Ingo Müller, Bernhard Schewe, Thomas Skutella, Willem E. Fibbe, Lothar Kanz, Hans-Jörg Bühring   +11 more
doaj   +1 more source