Results 21 to 30 of about 5,254,849 (303)

Mesenchymal Stem/Stromal Cells Derived from Dental Tissues: A Comparative In Vitro Evaluation of Their Immunoregulatory Properties Against T cells

Cells, 2019
Bone marrow mesenchymal stem/stromal cells (BM-MSCs) have immunoregulatory properties and have been used as immune regulators for the treatment of graft-versus-host disease (GVHD).
María del Pilar De la Rosa-Ruiz, Marco Antonio Álvarez-Pérez, Víctor Adrián Cortés-Morales, Alberto Monroy-García, Héctor Mayani, Gladis Fragoso-González, Sara Caballero-Chacón, Daniel Diaz, Fernando Candanedo-González, Juan José Montesinos   +9 more
doaj   +1 more source

Bone regeneration capacities of alveolar bone mesenchymal stem cells sheet in rabbit calvarial bone defect

Journal of Tissue Engineering, 2020
Mesenchymal stem cells sheets have been verified as a promising non-scaffold strategy for bone regeneration. Alveolar bone marrow mesenchymal stem cells, derived from neural crest, have the character of easily obtained and strong multi-differential ...
Yanan Liu, Haifeng Wang, Huixin Dou, Bin Tian, Le Li, Luyuan Jin, Zhenting Zhang, Lei Hu   +7 more
doaj   +1 more source

Human Mesenchymal Stem/Stromal Cells from Umbilical Cord Blood and Placenta Exhibit Similar Capacities to Promote Expansion of Hematopoietic Progenitor Cells In Vitro

Stem Cells International, 2017
Mesenchymal stem/stromal cells (MSCs) from bone marrow (BM) have been used in coculture systems as a feeder layer for promoting the expansion of hematopoietic progenitor cells (HPCs) for hematopoietic cell transplantation.
Guadalupe R. Fajardo-Orduña, Héctor Mayani, Patricia Flores-Guzmán, Eugenia Flores-Figueroa, Erika Hernández-Estévez, Marta Castro-Manrreza, Patricia Piña-Sánchez, Lourdes Arriaga-Pizano, Alejandro Gómez-Delgado, Alarcón-Santos Guadalupe, Odette Balvanera-Ortíz, Juan J. Montesinos   +11 more
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Umbilical cord mesenchymal stem cells for regenerative treatment of intervertebral disc degeneration

Frontiers in Cell and Developmental Biology, 2023
Intervertebral disc degeneration is thought to be a major contributor to low back pain, the etiology of which is complex and not yet fully understood. To compensate for the lack of drug and surgical treatment, mesenchymal stem cells have been proposed ...
Huagui Huang, Xin Liu, Jinzuo Wang, Moran Suo, Jing Zhang, Tianze Sun, Wentao Zhang, Zhonghai Li, Zhonghai Li   +8 more
doaj   +1 more source

Mesenchymal stem cells and the lung [PDF]

Respirology, 2013
AbstractMesenchymal stem cells (MSC) are a population of tissue‐resident adult progenitor cells that were originally identified in bone marrow, but have now been identified in many organs including the lung. Although their precise role in organ function remains incompletely defined, mounting evidence suggests that they are an important component of the
Sinclair, Kenneth, Yerkovich, Stephanie T., Chambers, Daniel C.   +2 more
openaire   +5 more sources

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study. [PDF]

, 2012
BACKGROUND: More than half of patients with multiple sclerosis have progressive disease characterised by accumulating disability. The absence of treatments for progressive multiple sclerosis represents a major unmet clinical need.
Kolappan, Madhan, Thompson, Alan J, Luan, Shi-Lu, Altmann, Daniel R, Crawley, Charles, Compston, Alastair, Patani, Rickie, Scott, Michael A, Du, Ming-Qing, Miller, David H, Michell, Andrew W, Chandran, Siddharthan, Connick, Peter, Webber, Daniel J   +13 more
core   +1 more source

Mesenchymal Stem Cells as Therapeutics [PDF]

Annual Review of Biomedical Engineering, 2010
Mesenchymal stem cells (MSCs) are multipotent cells that are being clinically explored as a new therapeutic for treating a variety of immune-mediated diseases. First heralded as a regenerative therapy for skeletal tissue repair, MSCs have recently been shown to modulate endogenous tissue and immune cells.
Biju, Parekkadan, Jack M, Milwid
openaire   +2 more sources

Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail

Stem Cells International, 2019
Human mesenchymal stem cells (MSCs) are good candidates for brain cell replacement strategies and have already been used as adjuvant treatments in neurological disorders.
Lorena V. Cortés-Medina, Herminia Pasantes-Morales, Alejandro Aguilera-Castrejon, Arturo Picones, Cesar O. Lara-Figueroa, Enoch Luis, Juan Jose Montesinos, Victor A. Cortés-Morales, M. P. De la Rosa Ruiz, Erika Hernández-Estévez, Laura C. Bonifaz, Marco Antonio Alvarez-Perez, Gerardo Ramos-Mandujano   +12 more
doaj   +1 more source

Prolonged ex vivo culture of human bone marrow mesenchymal stem cells influences their supportive activity toward NOD/SCID-repopulating cells and committed progenitor cells of B lymphoid and myeloid lineages

Haematologica, 2010
Background Bone marrow mesenchymal stem cells support proliferation and differentiation of hematopoietic progenitor cells in vitro. Since these cells constitute a rare subset of bone marrow cells, mesenchymal stem cell preparations for clinical purposes ...
Alexandra Briquet, Sophie Dubois, Sandrine Bekaert, Marie Dolhet, Yves Beguin, André Gothot   +5 more
doaj   +1 more source

Potential effects of mesenchymal stem cell derived extracellular vesicles and exosomal miRNAs in neurological disorders

Neural Regeneration Research, 2021
Mesenchymal stem cells are multipotent cells that possess anti-inflammatory, anti-apoptotic and immunomodulatory properties. The effects of existing drugs for neurodegenerative disorders such as Alzheimer’s disease are limited, thus mesenchymal stem cell
Masako Nakano, Mineko Fujimiya
doaj   +1 more source