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Homing of Mesenchymal Stem Cells [PDF]

open access: yesTransfusion Medicine and Hemotherapy, 2008
SUMMARY: Mesenchymal stem cells (MSCs) are primarily fibroblast-like cells. Yet, once studied under conditions of shear stress when flowing along endothelial cells in vitro or in blood vessels, as well as in classic migration assays such as chemotaxis assays, MSCs have recently been found to function similarly to leukocytes in many ways.
Reinhard, Henschler   +2 more
openaire   +2 more sources

The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Bone marrow microenvironment contains cellular and acellular compartments. The cellular compartment includes hematopoietic stem cells, mesenchymal stem cells and some other stromal cell types, while the acellular compartment is composed of scaffold ...
Mahshid Saleh   +4 more
doaj   +1 more source

Identification of Diagnostic Biomarkers by Bioinformatics Analysis in the Inflamed and Non-inflamed Intestinal Mucosa of Patients With Crohn’s Disease

open access: yesResearch in Molecular Medicine, 2021
Background: Crohn’s Disease (CD) is a type of inflammatory bowel disease that, despite its unknown etiology, is generally associated with genetics, immune system, and environmental factors. In this study, we uncover transcriptional signatures in patients
Mohsen Sheykhhasan   +5 more
doaj  

Immunoregulation by Mesenchymal Stem Cells: Biological Aspects and Clinical Applications

open access: yesJournal of Immunology Research, 2015
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into mesenchymal lineages and that can be isolated from various tissues and easily cultivated in vitro.
Marta E. Castro-Manrreza   +1 more
doaj   +1 more source

Odontogenic MSC Heterogeneity: Challenges and Opportunities for Regenerative Medicine

open access: yesFrontiers in Physiology, 2022
Cellular heterogeneity refers to the genetic and phenotypic differences among cells, which reflect their various fate choices, including viability, proliferation, self-renewal probability, and differentiation into different lineages.
Yuan Chen   +6 more
doaj   +1 more source

Mesenchymal Stem/Stromal Cells Derived from Dental Tissues: A Comparative In Vitro Evaluation of Their Immunoregulatory Properties Against T cells

open access: yesCells, 2019
Bone marrow mesenchymal stem/stromal cells (BM-MSCs) have immunoregulatory properties and have been used as immune regulators for the treatment of graft-versus-host disease (GVHD).
María del Pilar De la Rosa-Ruiz   +9 more
doaj   +1 more source

Bone regeneration capacities of alveolar bone mesenchymal stem cells sheet in rabbit calvarial bone defect

open access: yesJournal of Tissue Engineering, 2020
Mesenchymal stem cells sheets have been verified as a promising non-scaffold strategy for bone regeneration. Alveolar bone marrow mesenchymal stem cells, derived from neural crest, have the character of easily obtained and strong multi-differential ...
Yanan Liu   +7 more
doaj   +1 more source

Human Mesenchymal Stem/Stromal Cells from Umbilical Cord Blood and Placenta Exhibit Similar Capacities to Promote Expansion of Hematopoietic Progenitor Cells In Vitro

open access: yesStem Cells International, 2017
Mesenchymal stem/stromal cells (MSCs) from bone marrow (BM) have been used in coculture systems as a feeder layer for promoting the expansion of hematopoietic progenitor cells (HPCs) for hematopoietic cell transplantation.
Guadalupe R. Fajardo-Orduña   +11 more
doaj   +1 more source

Umbilical cord mesenchymal stem cells for regenerative treatment of intervertebral disc degeneration

open access: yesFrontiers in Cell and Developmental Biology, 2023
Intervertebral disc degeneration is thought to be a major contributor to low back pain, the etiology of which is complex and not yet fully understood. To compensate for the lack of drug and surgical treatment, mesenchymal stem cells have been proposed ...
Huagui Huang   +8 more
doaj   +1 more source

Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail

open access: yesStem Cells International, 2019
Human mesenchymal stem cells (MSCs) are good candidates for brain cell replacement strategies and have already been used as adjuvant treatments in neurological disorders.
Lorena V. Cortés-Medina   +12 more
doaj   +1 more source

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