Results 11 to 20 of about 361,860 (315)
The Regulation of Differentiation in Mesenchymal Stem Cells [PDF]
Mesenchymal stromal/stem cells (MSCs) are a population of stromal cells present in the bone marrow and most connective tissues, capable of differentiation into mesenchymal tissues such as bone and cartilage. MSCs are attractive candidates for biological cell-based tissue repair approaches because of their extensive proliferative ability in culture ...
Augello, Andrea, De Bari, Cosimo
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Homing of Mesenchymal Stem Cells [PDF]
SUMMARY: Mesenchymal stem cells (MSCs) are primarily fibroblast-like cells. Yet, once studied under conditions of shear stress when flowing along endothelial cells in vitro or in blood vessels, as well as in classic migration assays such as chemotaxis assays, MSCs have recently been found to function similarly to leukocytes in many ways.
Reinhard, Henschler +2 more
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The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells [PDF]
Bone marrow microenvironment contains cellular and acellular compartments. The cellular compartment includes hematopoietic stem cells, mesenchymal stem cells and some other stromal cell types, while the acellular compartment is composed of scaffold ...
Mahshid Saleh +4 more
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Background: Crohn’s Disease (CD) is a type of inflammatory bowel disease that, despite its unknown etiology, is generally associated with genetics, immune system, and environmental factors. In this study, we uncover transcriptional signatures in patients
Mohsen Sheykhhasan +5 more
doaj
Odontogenic MSC Heterogeneity: Challenges and Opportunities for Regenerative Medicine
Cellular heterogeneity refers to the genetic and phenotypic differences among cells, which reflect their various fate choices, including viability, proliferation, self-renewal probability, and differentiation into different lineages.
Yuan Chen +6 more
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Adipose-derived mesenchymal stromal/stem cells : tissue localization, characterization, and heterogeneity [PDF]
Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal ...
Helmut Geiger +3 more
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Immunoregulation by Mesenchymal Stem Cells: Biological Aspects and Clinical Applications
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into mesenchymal lineages and that can be isolated from various tissues and easily cultivated in vitro.
Marta E. Castro-Manrreza +1 more
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Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study. [PDF]
BACKGROUND: More than half of patients with multiple sclerosis have progressive disease characterised by accumulating disability. The absence of treatments for progressive multiple sclerosis represents a major unmet clinical need.
Kolappan, Madhan +13 more
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Bone marrow mesenchymal stem/stromal cells (BM-MSCs) have immunoregulatory properties and have been used as immune regulators for the treatment of graft-versus-host disease (GVHD).
María del Pilar De la Rosa-Ruiz +9 more
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Mesenchymal stem cells sheets have been verified as a promising non-scaffold strategy for bone regeneration. Alveolar bone marrow mesenchymal stem cells, derived from neural crest, have the character of easily obtained and strong multi-differential ...
Yanan Liu +7 more
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