Results 1 to 10 of about 84,888 (263)
Frontiers in Immunology, 2022 BackgroundSince the discovery of the immunomodulatory functions of mesenchymal stem cells (MSCs), their application in immunomodulation has attracted considerable attention, and an increasing number of studies have been conducted worldwide.
Zhongqing Wang +9 more
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BMC Immunology, 2021 Background Immuno-epidemiologists are often faced with multivariate outcomes, measured repeatedly over time. Such data are characterised by complex inter- and intra-outcome relationships which must be accounted for during analysis.
Lawrence Lubyayi +5 more
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Antileishmanial Activity of Flavones-Rich Fraction From Arrabidaea chica Verlot (Bignoniaceae)
Frontiers in Pharmacology, 2021 Acknowledging the need of identifying new compounds for the treatment of leishmaniasis, this study aimed to evaluate, from in vitro trials, the activity of flavones from Arrabidaea chica against L. amazonensis.
João Victor Silva-Silva +12 more
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PLOS Pathogens, 2021 Schistosomes are long lived, intravascular parasitic platyhelminths that infect >200 million people globally. The molecular mechanisms used by these blood flukes to dampen host immune responses are described in this review. Adult worms express a collection of host-interactive tegumental ectoenzymes that can cleave host signaling molecules such as ...
Sreemoyee Acharya +2 more
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npj VaccinesVaccine responses are sometimes impaired in rural, low-income settings. Helminth-associated gut barrier dysfunction and microbial translocation (MT) may be implicated. We used samples from a trial of praziquantel treatment-effects on vaccine responses in
Jacent Nassuuna +9 more
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Frontiers in Immunology, 2023 In recent years, there has been a tremendous development of biotechnological, pharmacological, and medical techniques which can be implemented in the functional modulation of the immune system components.
Martyna Strzelec +4 more
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Defining Human Regulatory T Cells beyond FOXP3: The Need to Combine Phenotype with Function
CellsRegulatory T cells (Tregs) are essential to maintain immune homeostasis by promoting self-tolerance. Reduced Treg numbers or functionality can lead to a loss of tolerance, increasing the risk of developing autoimmune diseases.
Chelsea Gootjes +3 more
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CASPASE-3 expression and activity in PBMCs associate with SARS-CoV-2 infection and clinical features
Clinical Immunology CommunicationsBackground: Although vaccines and treatments exist, new SARS-CoV-2 variants continue to emerge. An imbalance between apoptosis and autophagy may contribute to COVID-19 pathogenesis, leading to tissue damage and inflammation. Objective: To investigate the
Vanessa Mylenna Florêncio de Carvalho +7 more
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ESC Heart Failure, 2020 Aims Immunomodulation in heart failure (HF) has been studied in several randomized controlled trials (RCTs) with variable effects on cardiac structure, function, and outcomes.
Navkaranbir S. Bajaj +6 more
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Frontiers in Immunology, 2018 Obesity is accompanied by chronic systemic inflammation characterized by macrophage infiltration of obese tissues, an elevated plasma level of inflammatory substances, and excessive accumulation of lipids.
Min-Kyung Shin +17 more
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