Results 11 to 20 of about 109,666 (292)

Effects of immunomodulation in classic infantile Pompe patients with high antibody titers [PDF]

Orphanet Journal of Rare Diseases, 2019
Purpose To evaluate whether immunomodulation can eliminate high sustained antibody levels, and thereby improve clinical outcome in classic infantile Pompe patients receiving enzyme replacement therapy (ERT) with recombinant human alpha-glucosidase (rhGAA)
E. Poelman, M. Hoogeveen-Westerveld, J. M. P. van den Hout, R. G. M. Bredius, A. C. Lankester, G. J. A. Driessen, S. S. M. Kamphuis, W. W. M. Pijnappel, A. T. van der Ploeg   +8 more
doaj   +2 more sources

Endothelial β-Catenin Deficiency Causes Blood-Brain Barrier Breakdown via Enhancing the Paracellular and Transcellular Permeability

Frontiers in Molecular Neuroscience, 2022
Disruption of the blood-brain barrier (BBB) causes or contributes to neuronal dysfunction and several central nervous system (CNS) disorders. Wnt/β-catenin signaling is essential for maintaining the integrity of the adult BBB in physiological and ...
Basharat Hussain, Basharat Hussain, Cheng Fang, Xiaowen Huang, Ziying Feng, Ziying Feng, Yuxuan Yao, Yu Wang, Junlei Chang   +8 more
doaj   +1 more source

Effect of birth weight, exclusive breastfeeding and growth in infancy on fat mass and fat free mass indices in early adolescence: an analysis of the Entebbe Mother and Baby Study (EMaBs) cohort [version 2; peer review: 1 approved, 2 approved with reservations]

AAS Open Research, 2020
Background: There is limited data from Africa on the effect of pre- and post-natal growth and infant feeding on later body composition. This study's aim was to investigate the effect of birth weight, exclusive breastfeeding and infant growth on ...
Jonathan Nsamba, Swaib A. Lule, Benigna Namara, Christopher Zziwa, Hellen Akurut, Lawrence Lubyayi, Florence Akello, Josephine Tumusiime, Alison M. Elliott, Emily L. Webb   +9 more
doaj   +1 more source

AWP1 Restrains the Aggressive Behavior of Breast Cancer Cells Induced by TNF-α

Frontiers in Oncology, 2021
TNF-α plays a crucial role in cancer initiation and progression by enhancing cancer cell proliferation, survival, and migration. Even though the known functional role of AWP1 (zinc finger AN1 type-6, ZFAND6) is as a key mediator of TNF-α signaling, its ...
Eun-Young Kim, Eun-Young Kim, Ji-Eun Kim, Ji-Eun Kim, Bongkun Choi, Bongkun Choi, Jiyeon Kweon, Jiyeon Kweon, Si-On Park, Si-On Park, Hee-Seop Lee, Hee-Seop Lee, Eun-Jin Lee, Eun-Jin Lee, Soyoon Oh, Soyoon Oh, Ha Rim Shin, Ha Rim Shin, Hyuksu Choi, Hyuksu Choi, Yongsub Kim, Yongsub Kim, Eun-Ju Chang, Eun-Ju Chang, Eun-Ju Chang   +24 more
doaj   +1 more source

Immunomodulation of dendritic cells in autoimmune type 1 diabetes mellitus.

, 2007
Immunomodulation of dendritic cells in autoimmune type 1 diabetes ...
Donald Milan. Cheatem (7999433)
core   +4 more sources

Implications of helminth immunomodulation on COVID-19 co-infections [PDF]

, 2021
Coronavirus disease 2019 (COVID-19) and helminths infections can be in a synergistic epidemic in developing and suburban areas of industrialized countries.
Chacon, Nathalie, Chacin-Bonilla, Leonor, Cesar, Italo M., Nathalie Chacon, Italo M., Leonor Chacin-Bonilla   +5 more
core   +1 more source

Effects of immunomodulation on thyroid autoimmunity.

, 2004
Effects of immunomodulation on thyroid ...
Eryn. Gangi (7963277)
core   +3 more sources

Allergen Immunotherapy and Tolerance

Allergology International, 2013
Successful allergen-specific immunotherapy (AIT) is associated with a marked decrease in symptoms on allergen exposure, a reduced requirement for 'rescue' anti-allergic drugs and improvement in patients' quality of life.
Tomokazu Matsuoka, Mohamed H Shamji, Stephen R Durham   +2 more
doaj   +1 more source

Dissecting the role of CSF2RB expression in human regulatory T cells

Frontiers in Immunology, 2022
Colony stimulating factor 2 receptor subunit beta (CSF2RB; CD131) is the common subunit of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5. Interestingly, FOXP3+ regulatory T cells (
Beatriz F. Côrte-Real, Beatriz F. Côrte-Real, Rebeca Arroyo Hornero, Rebeca Arroyo Hornero, Aleksandra Dyczko, Aleksandra Dyczko, Ibrahim Hamad, Ibrahim Hamad, Markus Kleinewietfeld, Markus Kleinewietfeld, Markus Kleinewietfeld   +10 more
doaj   +1 more source

Anti-COVID-19 drug candidates: A review on potential biological activities of natural products in the management of new coronavirus infection

Journal of Traditional and Complementary Medicine, 2021
Background and aim: The novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now become a worldwide pandemic bringing over 71 million confirmed cases, while the specific drugs and vaccines ...
Anchalee Prasansuklab, Atsadang Theerasri, Panthakarn Rangsinth, Chanin Sillapachaiyaporn, Siriporn Chuchawankul, Tewin Tencomnao   +5 more
doaj   +1 more source