Results 11 to 20 of about 96,912 (310)

Effects of immunomodulation in classic infantile Pompe patients with high antibody titers [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2019
Purpose To evaluate whether immunomodulation can eliminate high sustained antibody levels, and thereby improve clinical outcome in classic infantile Pompe patients receiving enzyme replacement therapy (ERT) with recombinant human alpha-glucosidase (rhGAA)
E. Poelman   +8 more
doaj   +2 more sources

Gold nanoclusters potentially facilitate dentin regeneration by functioning immunomodulation [PDF]

open access: yes, 2022
It is presently difficult to achieve dental pulp vitality maintenance and regeneration in adult teeth. Dentin destruction results in the exposure of the dental pulp tissue to infectious oral environments, thereby triggering continuous severe pulp ...
Liu, Tianqing   +5 more
core   +1 more source

Blood–Brain Barrier Breakdown: An Emerging Biomarker of Cognitive Impairment in Normal Aging and Dementia

open access: yesFrontiers in Neuroscience, 2021
The blood–brain barrier (BBB) plays a vital role in maintaining the specialized microenvironment of the neural tissue. It separates the peripheral circulatory system from the brain parenchyma while facilitating communication.
Basharat Hussain   +3 more
doaj   +1 more source

Human Cytomegalovirus-Induced Degradation of CYTIP Modulates Dendritic Cell Adhesion and Migration

open access: yesFrontiers in Immunology, 2017
As potent antigen-presenting cells, dendritic cells (DCs) are essential for the initiation of effective antiviral immune responses. Viruses and especially herpesviruses, which are able to establish lifelong persistence, exploit several immune evasion ...
Christiane S. Heilingloh   +7 more
doaj   +1 more source

Effect of birth weight, exclusive breastfeeding and growth in infancy on fat mass and fat free mass indices in early adolescence: an analysis of the Entebbe Mother and Baby Study (EMaBs) cohort [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesAAS Open Research, 2020
Background: There is limited data from Africa on the effect of pre- and post-natal growth and infant feeding on later body composition. This study's aim was to investigate the effect of birth weight, exclusive breastfeeding and infant growth on ...
Jonathan Nsamba   +9 more
doaj   +1 more source

AWP1 Restrains the Aggressive Behavior of Breast Cancer Cells Induced by TNF-α

open access: yesFrontiers in Oncology, 2021
TNF-α plays a crucial role in cancer initiation and progression by enhancing cancer cell proliferation, survival, and migration. Even though the known functional role of AWP1 (zinc finger AN1 type-6, ZFAND6) is as a key mediator of TNF-α signaling, its ...
Eun-Young Kim   +24 more
doaj   +1 more source

The Role of Immune Cells in Post-Stroke Angiogenesis and Neuronal Remodeling: The Known and the Unknown

open access: yesFrontiers in Immunology, 2021
Following a cerebral ischemic event, substantial alterations in both cellular and molecular activities occur due to ischemia-induced cerebral pathology.
Yinzhong Ma   +4 more
doaj   +1 more source

Schistosome immunomodulators

open access: yesPLOS Pathogens, 2021
Schistosomes are long lived, intravascular parasitic platyhelminths that infect >200 million people globally. The molecular mechanisms used by these blood flukes to dampen host immune responses are described in this review. Adult worms express a collection of host-interactive tegumental ectoenzymes that can cleave host signaling molecules such as ...
Sreemoyee Acharya   +2 more
openaire   +4 more sources

Viral presence-guided immunomodulation in lymphocytic myocarditis: an update

open access: yes, 2021
Latest statements from European and American societies recommend to rule out viral presence in endomyocardial biopsy (EMB) via polymerase chain reaction (PCR) analysis before starting immunosuppression or immunomodulation in acute lymphocytic myocarditis
Artico J.   +6 more
core   +1 more source

Allergen Immunotherapy and Tolerance

open access: yesAllergology International, 2013
Successful allergen-specific immunotherapy (AIT) is associated with a marked decrease in symptoms on allergen exposure, a reduced requirement for 'rescue' anti-allergic drugs and improvement in patients' quality of life.
Tomokazu Matsuoka   +2 more
doaj   +1 more source

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