Results 11 to 20 of about 106,431 (292)

Blood–Brain Barrier Breakdown: An Emerging Biomarker of Cognitive Impairment in Normal Aging and Dementia

open access: yesFrontiers in Neuroscience, 2021
The blood–brain barrier (BBB) plays a vital role in maintaining the specialized microenvironment of the neural tissue. It separates the peripheral circulatory system from the brain parenchyma while facilitating communication.
Basharat Hussain   +3 more
doaj   +1 more source

Human Cytomegalovirus-Induced Degradation of CYTIP Modulates Dendritic Cell Adhesion and Migration

open access: yesFrontiers in Immunology, 2017
As potent antigen-presenting cells, dendritic cells (DCs) are essential for the initiation of effective antiviral immune responses. Viruses and especially herpesviruses, which are able to establish lifelong persistence, exploit several immune evasion ...
Christiane S. Heilingloh   +7 more
doaj   +1 more source

Endothelial β-Catenin Deficiency Causes Blood-Brain Barrier Breakdown via Enhancing the Paracellular and Transcellular Permeability

open access: yesFrontiers in Molecular Neuroscience, 2022
Disruption of the blood-brain barrier (BBB) causes or contributes to neuronal dysfunction and several central nervous system (CNS) disorders. Wnt/β-catenin signaling is essential for maintaining the integrity of the adult BBB in physiological and ...
Basharat Hussain   +8 more
doaj   +1 more source

Immunomodulation of dendritic cells in autoimmune type 1 diabetes mellitus.

open access: yes, 2007
Immunomodulation of dendritic cells in autoimmune type 1 diabetes ...
Donald Milan. Cheatem (7999433)
core   +6 more sources

Effect of birth weight, exclusive breastfeeding and growth in infancy on fat mass and fat free mass indices in early adolescence: an analysis of the Entebbe Mother and Baby Study (EMaBs) cohort [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesAAS Open Research, 2020
Background: There is limited data from Africa on the effect of pre- and post-natal growth and infant feeding on later body composition. This study's aim was to investigate the effect of birth weight, exclusive breastfeeding and infant growth on ...
Jonathan Nsamba   +9 more
doaj   +1 more source

AWP1 Restrains the Aggressive Behavior of Breast Cancer Cells Induced by TNF-α

open access: yesFrontiers in Oncology, 2021
TNF-α plays a crucial role in cancer initiation and progression by enhancing cancer cell proliferation, survival, and migration. Even though the known functional role of AWP1 (zinc finger AN1 type-6, ZFAND6) is as a key mediator of TNF-α signaling, its ...
Eun-Young Kim   +24 more
doaj   +1 more source

Allergen Immunotherapy and Tolerance

open access: yesAllergology International, 2013
Successful allergen-specific immunotherapy (AIT) is associated with a marked decrease in symptoms on allergen exposure, a reduced requirement for 'rescue' anti-allergic drugs and improvement in patients' quality of life.
Tomokazu Matsuoka   +2 more
doaj   +1 more source

Dissecting the role of CSF2RB expression in human regulatory T cells

open access: yesFrontiers in Immunology, 2022
Colony stimulating factor 2 receptor subunit beta (CSF2RB; CD131) is the common subunit of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5. Interestingly, FOXP3+ regulatory T cells (
Beatriz F. Côrte-Real   +10 more
doaj   +1 more source

Anti-COVID-19 drug candidates: A review on potential biological activities of natural products in the management of new coronavirus infection

open access: yesJournal of Traditional and Complementary Medicine, 2021
Background and aim: The novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now become a worldwide pandemic bringing over 71 million confirmed cases, while the specific drugs and vaccines ...
Anchalee Prasansuklab   +5 more
doaj   +1 more source

Unsupervised title and abstract screening for systematic review: a retrospective case-study using topic modelling methodology

open access: yesSystematic Reviews, 2023
Background The importance of systematic reviews in collating and summarising available research output on a particular topic cannot be over-emphasized.
Agnes Natukunda, Leacky K. Muchene
doaj   +1 more source

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