Results 41 to 50 of about 106,431 (292)

Ethnobotanical survey, anthelmintic effects and cytotoxicity of plants used for treatment of helminthiasis in the Central and Kara regions of Togo

BMC Complementary Medicine and Therapies, 2020
Background Traditional medicines are the main source of treatment of helminthiasis in endemic areas of Togo. The present study aimed to investigate the plants used by Traditional healers (THs) to treat helminth infections in endemic communities within ...
Essoham Ataba, Gnatoulma Katawa, Manuel Ritter, Adjoa Holali Ameyapoh, Kokou Anani, Oukoe M. Amessoudji, Pélagie Edlom Tchadié, Tchadjabo Tchacondo, Komlan Batawila, Yaovi Ameyapoh, Achim Hoerauf, Laura E. Layland, Simplice D. Karou   +12 more
doaj   +1 more source

Tumor Microenvironment: Key Players in Triple Negative Breast Cancer Immunomodulation

, 2021
Triple negative breast cancer (TNBC) is a heterogeneous disease and is highly related to immunomodulation. As we know, the most effective approach to treat TNBC so far is still chemotherapy.
Xinhong Wu, Dipali Sharma, Sumit Siddharth, Sheetal Parida, Hongmei Zheng   +4 more
core   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Global scientific trends on the immunomodulation of mesenchymal stem cells in the 21st century: A bibliometric and visualized analysis

Frontiers in Immunology, 2022
BackgroundSince the discovery of the immunomodulatory functions of mesenchymal stem cells (MSCs), their application in immunomodulation has attracted considerable attention, and an increasing number of studies have been conducted worldwide.
Zhongqing Wang, Yuqiang Sun, Rou Shen, Rou Shen, Xia Tang, Xia Tang, Yingxin Xu, Ye Zhang, Yao Liu, Yao Liu   +9 more
doaj   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto, Dariia Kliushnikova, Richard Friedrich Radlberger, Sinan Yasaroglu, Tobias Moser, Andrea Harrer, Kitty Kratzer, Wolfgang Hitzl, Christiane Gradl, Martin Schmidauer, Patrick Roth, Harald Hegen, Peter Wipfler   +12 more
wiley   +1 more source

Helminth driven gut inflammation and microbial translocation associate with altered vaccine responses in rural Uganda

npj Vaccines
Vaccine responses are sometimes impaired in rural, low-income settings. Helminth-associated gut barrier dysfunction and microbial translocation (MT) may be implicated. We used samples from a trial of praziquantel treatment-effects on vaccine responses in
Jacent Nassuuna, Joas Sterk, Bridgious Walusimbi, Agnes Natukunda, Ronald Nkangi, Rebecca Amongin, Ludoviko Zirimenya, Emily L. Webb, Alison M. Elliott, Gyaviira Nkurunungi   +9 more
doaj   +1 more source

Analysis of multivariate longitudinal immuno-epidemiological data using a pairwise joint modelling approach

BMC Immunology, 2021
Background Immuno-epidemiologists are often faced with multivariate outcomes, measured repeatedly over time. Such data are characterised by complex inter- and intra-outcome relationships which must be accounted for during analysis.
Lawrence Lubyayi, Patrice A. Mawa, Stephen Cose, Alison M. Elliott, Jonathan Levin, Emily L. Webb   +5 more
doaj   +1 more source

Metabolic Reconfiguration Activates Stemness and Immunomodulation of PDLSCs

, 2022
Periodontal ligament derived stem cells (PDLSC) are adult multipotent mesenchymal-like stem cells (MSCs) that can induce a promising immunomodulation to interact with immune cells for disease treatment.
Wenjing Yu, Ranran Huang, Chider Chen, Wen Li, Payal Arora, Qian Jiang, Xiaobin Huang   +6 more
core   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Defining Human Regulatory T Cells beyond FOXP3: The Need to Combine Phenotype with Function

Cells
Regulatory T cells (Tregs) are essential to maintain immune homeostasis by promoting self-tolerance. Reduced Treg numbers or functionality can lead to a loss of tolerance, increasing the risk of developing autoimmune diseases.
Chelsea Gootjes, Jaap Jan Zwaginga, Bart O. Roep, Tatjana Nikolic   +3 more
doaj   +1 more source